A revised surgical concept of anterior cruciate ligament replacement in a rabbit model : preliminary investigations

• Autorzy: Ficek K. , Wieczorek J. , Stodolak-Zych E. , Kosenyuk Y.
• Języki publikacji: EN

Abstrakty

EN

In this project the anterior cruciate ligament (ACL) replacement in a rabbit model was performed for the preclinical phase of investigations of a new form of biomaterial i.e. polymer beads (granules). This material, based on resorbable aliphatic polyester (polylactide - PLA) was used as a filler of the bone tunnels to enhance tendon-to-bone healing. The high specific surface area and well known biocompatibility of this material designated it as an osteoconductive agent in reconstructive ligament surgery. Additionally, a new surgical concept was proposed which retains the natural elasticity of the harvested tendon. This method ensures fixation of the grafted tendon within the bone tunnels in their entire length.

Słowa kluczowe

EN

ACL reconstruction; tendon implant; resorbable material

• Wydawca: Polish Society for Biomaterials in Cracow
• Czasopismo: Engineering of Biomaterials
• Rocznik: 2012
• Tom: Vol. 15, no. 113
• Strony: 33--34
• Opis fizyczny: Bibliogr. 6 poz., rys.

Twórcy

autor

Ficek K.

• Galen - Orthopaedics, 6 Jerzego St., 43-150 Bierun, Poland

autor

Wieczorek J.

• National Research Institute of Ammal Production, Department of Biotechnology Reproduction Animals, 1 Krakowska St., 32-083 Bauce, Poland

autor

Stodolak-Zych E.

• AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Biomaterials, 30 Mickiewicz Av, 30-059 Krakow, Poland

autor

Kosenyuk Y.

• National Research Institute of Ammal Production, Department of Biotechnology Reproduction Animals, 1 Krakowska St., 32-083 Bauce, Poland

Bibliografia

• [1] Miller S.L., Gladstone J.N.: Graft selection in anterior cruciate ligament reconstruction. Orthopedic Clinics of North America 33, 4 (2002) 675-683.
• [2] Strickland S.M., MacGillivray J.D., Warren R.F.: Anterior cruciate ligament reconstruction with allograft tendons. Orthopedic Clinics of North America 34 (2003) 41-47.
• [3] Paul Neuman, et al.: Prevalence of Tibiofemoral Osteoarthritis 15 Years After Nonoperative Treatment of Anterior Cruciate Ligament Injury. American Journal of Sports Medicine 36 (2008) 1717-1725.
• [4] Bruce D. Beynnon, et al.: Anterior Cruciate Ligament Replacement: Comparison of Bone-Patellar Tendon-Bone Grafts with Two-Strand Hamstring Grafts. Journal of Bone and Joint Surgery 84 (2002) 1503-1513.
• [5] Gogolewski S., Gugała Z.; Differentiation, growth and activity of rat bone marrow stromal cells on resorbable poly(L/DL - lactide) membrane. Biomaterials 25 (2004) 2299-2307.
• [6] Chen F-M., Zhang J., Zhang M., An Y., Chen F., Wu Z-F.: A review on endogenous regenerative technology in periodontal regenerative medicine. Biomaterials 31 (2010) 7892-7927.