On influence of anodic oxidation on thrombogenicity and bioactivity of the Ti-13Nb- 13Zr alloy

• Autorzy: Szymonowicz M. , Kazek-Kęsik A. , Sowa M. , Żywicka B , Rybak Z. , Simka W.

Identyfikatory

DOI

0.5277/ABB-00625-2016-03

• Języki publikacji: EN

Abstrakty

EN

Purpose: This paper reports the results of investigations of the blood response of the modified titanium alloys surfaces. Methods: To enhance biocompatibility of the Ti-13Nb-13Zr alloy, anodisation was performed at 80 and 150 V. The oxidation process was carried out in a solution containing 4 mol dm−3 H3PO4 and 0.59 mol dm−3 Ca(H2PO2)2. Results: The haemolytic activity of the titanium alloy surface was not altered much by the anodisation. The obtained values of the percentage of haemolysis were well below the levels required for the materials intended for blood contact. The clotting time of the blood was similar for the as-ground sample and the sample anodised at 80 V. For the sample anodised at 150 V the clotting time was shorter. The differences between these samples were observed in partial thromboplastin time after activation, prothrombin time and thrombin time, after 24 h. Extracts taken from the samples were not toxic towards the L-929 mouse fibroblast cells. Conclusions: The proposed treatment might be appropriate for the preparation of the modified Ti-13Nb-13Zr surfaces intended for bone reconstruction or cardiovascular implants depending on process parameters.

Słowa kluczowe

EN

vanadium-free titanium alloys; anodic oxidation; surface modification; blood compatibility

PL

stopy tytanu; utlenianie anodowe; modyfikacja powierzchni; krew

• Wydawca: Oficyna Wydawnicza Politechniki Wrocławskiej
• Czasopismo: Acta of Bioengineering and Biomechanics
• Rocznik: 2017
• Tom: Vol. 19, no. 2
• Strony: 41--50
• Opis fizyczny: Bibliogr. 28 poz., rys., tab., wykr.

Twórcy

autor

Szymonowicz M.

• Department of Experimental Surgery and Biomaterials Research, Wroclaw Medical University, Poland

autor

Kazek-Kęsik A.

• Faculty of Chemistry, Silesian University of Technology, Poland

autor

Sowa M.

• Faculty of Chemistry, Silesian University of Technology, Poland

autor

Żywicka B

• Department of Experimental Surgery and Biomaterials Research, Wroclaw Medical University, Poland

autor

Rybak Z.

• Department of Experimental Surgery and Biomaterials Research, Wroclaw Medical University, Poland

autor

Simka W.

• Faculty of Chemistry, Silesian University of Technology, Poland

Bibliografia

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Uwagi

Opracowanie ze środków MNiSW w ramach umowy 812/P-DUN/2016 na działalność upowszechniającą naukę (zadania 2017).