Pharmacokinetics and bioavailability of curdione in mice by UPLC-MS/MS

• Autorzy: Liang Qishun , Chen Tianyu , Luo Lvqi , Ma Yizhe , Wen Congcong , Huang Xueli

Identyfikatory

DOI

10.1556/1326.2022.01020

• Języki publikacji: EN

Abstrakty

EN

A UPLC-MS/MS method was developed to determinate curdione in the mouse blood, and the pharmacokinetics of curdione in mice after intravenous (5 mg kg⁻¹) and oral (20 mg kg⁻¹) administration were studied. The HSS T3 column was used for separation, and column temperature was set at 40 °C. Multiple reaction monitoring (MRM) mode were used for determination of curdione. Blood samples were taken from the caudal vein of Institute of Cancer Research (ICR) mice after administration of curdione. It showed a good linear relationship in the range of 1–500 ng mL⁻¹ (r > 0.998); the intra-day precision was <13%, the inter-day precision was <15%, and the accuracy was 90%–105%, the recovery was >77%, and the matrix effect was 97%–107%. The half-life was relatively short, and the bioavailability was 6.5%. The developed method was suitable for the pharmacokinetics of curdione in mice.

Słowa kluczowe

EN

curdione; UPLC-MS/MS; pharmacokinetics; bioavailability; mouse

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2023
• Tom: Vol. 35, no. 2
• Strony: 144--148
• Opis fizyczny: Bibliogr. 38 poz., rys., tab., wykr.

Twórcy

autor

Liang Qishun

• Laboratory Animal Centre, Wenzhou Medical University, Wenzhou, China

autor

Chen Tianyu

• Fundus Disease Center, Eye Hospital, Wenzhou Medical University, China

autor

Luo Lvqi

• Laboratory Animal Centre, Wenzhou Medical University, Wenzhou, China

autor

Ma Yizhe

• Laboratory Animal Centre, Wenzhou Medical University, Wenzhou, China

autor

Wen Congcong

• Laboratory Animal Centre, Wenzhou Medical University, Wenzhou, China

autor

Huang Xueli

• Analytical and Testing Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China

• https://orcid.org/0000-0003-0901-0187

Bibliografia

• 1. Cui, Y.Y.; Liu, J.G.; Zhao, F.H.; Shi, D.Z. Zhongguo Zhong Yao Za Zhi 2015, 40, 1230–4.
• 2. Qian, W.; Zhao, F.H.; Shi, D.Z. Zhongguo Zhong Xi Yi Jie He Za Zhi 2012, 32, 575–6.
• 3. Han, H.; Wang, L.; Liu, Y.; Shi, X.; Zhang, X.; Li, M.; Wang, T. Food Funct. 2019, 10, 224–34.
• 4. Loc, N.H.; Diem, D.T.; Binh, D.H.; Huong, D.T.; Kim, T.G.; Yang, M.S. Mol. Biotechnol. 2008, 38, 81–7.
• 5. Tariq, S.; Imran, M.; Mushtaq, Z.; Asghar, N. Lipids Health Dis. 2016, 15, 39.
• 6. Liu, P.; Miao, K.; Zhang, L.; Mou, Y.; Xu, Y.; Xiong, W.; Yu, J.; Wang, Y. Respir. Res. 2020, 21, 58.
• 7. Wu, Z.; Zai, W.; Chen, W.; Han, Y.; Jin, X.; Liu, H. J. Cardiovasc. Pharmacol. 2019, 74, 118–27.
• 8. Fang, H.; Gao, B.; Zhao, Y.; Fang, X.; Bian, M.; Xia, Q. Phytomedicine 2019, 61, 152859.
• 9. Zhang, D.; Qiao, W.; Zhao, Y.; Fang, H.; Xu, D.; Xia, Q. Fitoterapia 2017, 116, 106–15.
• 10. Li, X.J.; Liang, L.; Shi, H.X.; Sun, X.P.; Wang, J.; Zhang, L.S. Neuropsychiatr Dis. Treat. 2017, 13, 1733–40.
• 11. Kong, Q.; Ma, Y.; Yu, J.; Chen, X. Sci. Rep. 2017, 7, 15543.
• 12. Hong, B.; Li, W.; Dong, M.; Niu, Y. Pak. J. Pharm. Sci. 2017, 30, 809–16.
• 13. Li, J.; Bian, W.H.; Wan, J.; Zhou, J.; Lin, Y.; Wang, J.R.; Wang, Z.X.; Shen, Q.; Wang, K.M. Asian Pac. J. Cancer Prev. 2014, 15, 9997–10001.
• 14. Kong, Q.; Sun, F.; Chen, X. Cell J. 2013, 15, 160–5.
• 15. Oh, O.J.; Min, H.Y.; Lee, S.K. Arch. Pharm. Res. 2007, 30, 1236–9.
• 16. Hou, X.L.; Hayashi-Nakamura, E.; Takatani-Nakase, T.; Tanaka, K.; Takahashi, K.; Komatsu, K.; Takahashi, K. Evid Based Complement Alternat Med. 2011, 2011, 913898.
• 17. Ma, X.C.; Zheng, J.; Wu, L.J.; Guo, D.A. Magn. Reson. Chem. 2007, 45, 90–2.
• 18. Xia, Q.; Wang, X.; Xu, D.J.; Chen, X.H.; Chen, F.H. Thromb. Res. 2012, 130, 409–14.
• 19. Li, J.; Mao, C.; Li, L.; Ji, D.; Yin, F.; Lang, Y.; Lu, T.; Xiao, Y.; Li, L. J. Pharm. Biomed. Anal. 2014, 95, 146–50.
• 20. Lv, D.; Cao, Y.; Dong, X.; Chen, X.; Lou, Z.; Chai, Y. Biomed. Chromatogr. 2014, 28, 782–7.
• 21. Ma, J.; Dong, J.; Lin, G.; Yue, L.; Xiang, Z.; Xu, R.; Hu, L.; Wang, X. Biomed. Chromatogr. 2012, 26, 655–9.
• 22. Meng, X.; Zhang, T.; Li, Y.; Pan, Q.; Jiang, J.; Luo, Y.; Chong, L.; Yang, Y.; Xu, S.; Zhou, L.; Sun, Z. Biomed. Chromatogr. 2015, 29, 1499–505.
• 23. Peng, Y.; Zhang, M.; Li, W.; Liu, B.; Wu, H.; Jiang, F.; Zhao, L.; Zhu, H. Biomed. Chromatogr. 2014, 28, 1360–5.
• 24. Wang, B.; Yang, S.; Sheng, L.; Li, Y. Biomed. Chromatogr. 2015, 29, 1393–8.
• 25. Yu, X.; Liu, H.; Xu, X.; Hu, Y.; Wang, X.; Wen, C. J. Chromatogr. B-Anal. Technol. Biomed. Life Sci. 2021, 1179.
• 26. Chen, F.; Yu, Z.; Wang, X. J. Chromatogr. B-Anal. Technol. Biomed. Life Sci. 2021, 1180.
• 27. Yang, J.; Zeng, G.; Ma, J.; Wang, X.; Zhou, Q. J. Anal. Methods Chem. 2021, 2021.
• 28. Wen, C.; Zhou, C.; Jin, Y.; Hu, Y.; Wang, H.; Wang, X.; Yang, X. Curr. Pharm. Anal. 2021, 17, 602–12.
• 29. Sun, W.; Jiang, X.; Wang, X.; Bao, X. Curr. Pharm. Anal. 2021, 17, 547–53.
• 30. Jin, Y.X.; Chen, Y.Y.; Liu, J.W.; Bao, X.; Zhi, Y.H.; Wen, C.R.; Zhu, W.Z. Acta Chromatogr. 2020, 32, 194–8.
• 31. Tong, S.H.; Zeng, Y.Q.; Ma, J.S.; Wen, C.C. Acta Chromatogr. 2021, 33, 333–7.
• 32. Shen, X.; Dai, X.; He, Y.; Wen, C.; Zhang, Q. Int. J. Anal. Chem. 2022, 2022, 3401355.
• 33. Wen, C.; Chen, M.; Zhao, L.; Yu, Y.; Deng, M.; Wang, Z. Lat. Am. J. Pharm. 2013, 32, 1102–6.
• 34. Geng, P.; Wang, C.; He, Y.; Liu, Z.; Yang, S.; Lin, Y.; Wen, C.; Lin, K. Lat. Am. J. Pharm. 2015, 34, 748–53.
• 35. Jin, C.; Ying, W.; Ke, R.; Wen, C.; Chen, X. Lat. Am. J. Pharm. 2015, 34, 843–7.
• 36. Patil, P.J.; Usman, M.; Zhang, C.; Mehmood, A.; Zhou, M.; Teng, C.; Li, X. Compr. Rev. Food Sci. Food Saf. 2022, 21, 1732–76.
• 37. Leung, M.F.; Cheung, P.C.K. Int. J. Med. Mushrooms 2021, 23, 1–15.
• 38. Yao, Y.; Tan, P.; Kim, J.E. Nutr. Rev. 2022, 80, 741–61.