Observer-based linear state-dependent control for blood glucose regulation in type 1 diabetic patients with unknown delays

• Autorzy: Castro-Gómez J. , Targui B. , Hernández-González O. , Valencia-Palomo G. , Guerrero-Sánchez M. E.

Identyfikatory

DOI

10.1016/j.bbe.2025.02.003

• Języki publikacji: EN

Abstrakty

EN

This paper presents a control strategy for blood glucose regulation in the presence of a time-varying delayed input, where the delay is unknown. The proposed control scheme is based on an observer-based linear state-dependent (LSD) (a subclass of the general linear parameter varying (LPV) framework) control with 𝐻_∞ criterion. This proposed control regulates glucose levels in response to meal intake. A novel LSD system representation is used to relax the inherent conservativeness of the nonlinear system. First, the observer achieves an estimate of the current state vector despite the delayed input, where the time-varying unknown delay can be relatively long. Thus, the control law will perform well in the presence of a long unknown delay. The observer-based control scheme is validated by considering different meal disturbances and unknown delay scenarios.

Słowa kluczowe

EN

nonlinear system; unknown time delay; observer-based control; physiological system; diabetes type 1

PL

opóźnienie czasowe; układ fizjologiczny; cukrzyca typu 1

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2025
• Tom: Vol. 45, iss. 2
• Strony: 189--198
• Opis fizyczny: Bibliogr. 26 poz., rys., tab., wykr.

Twórcy

autor

Castro-Gómez J.

• Tecnológico Nacional de México, IT Hermosillo, Av. Tec. 115, Hermosillo, 83170, Sonora, Mexico

autor

Targui B.

• Faculty of Science and Technology, Department of Electrical Engineering, Abdelhamid Ibn Badis University of Mostaganem, Belhacel road, Mostaganem, 27000, Algeria

• https://orcid.org/0000-0002-6412-581X

autor

Hernández-González O.

• Tecnológico Nacional de México, IT Hermosillo, Av. Tec. 115, Hermosillo, 83170, Sonora, Mexico

• https://orcid.org/0000-0002-5870-556X

autor

Valencia-Palomo G.

• Tecnológico Nacional de México, IT Hermosillo, Av. Tec. 115, Hermosillo, 83170, Sonora, Mexico

• https://orcid.org/0000-0002-3382-8213

autor

Guerrero-Sánchez M. E.

• Tecnológico Nacional de México, IT Hermosillo, Av. Tec. 115, Hermosillo, 83170, Sonora, Mexico
• IIxM SECIHTI-Tecnológico Nacional de México, IT Hermosillo, Av. Tec. 115, Hermosillo, 83170, Sonora, Mexico

• https://orcid.org/0000-0001-5256-6266

Bibliografia

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa nr POPUL/SP/0154/2024/02 w ramach programu "Społeczna odpowiedzialność nauki II" - moduł: Popularyzacja nauki (2025).