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Dose assessment in high dose rate brachytherapy with cobalt-60 source for cervical cancer treatment: a phantom study

Identyfikatory
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Transition from low dose rate brachytherapy to high dose rate brachytherapy at our department necessitated the performance of dose verification test, which served as an end-to-end quality assurance procedure to verify and validate dose delivery in intracavitary brachytherapy of the cervix and the vaginal walls based on the Manchester system. An inhouse water phantom was designed and constructed from Perspex sheets to represent the cervix region of a standard adult patient. The phantom was used to verify the whole dose delivery chain such as calibration of the cobalt-60 source in use, applicator, and source localization method, the output of treatment planning with dedicated treatment planning system, and actual dose delivery process. Since the above factors would influence the final dose delivered, doses were measured with calibrated gafchromic EBT3 films at various points within the in-house phantom for a number of clinical implants that were used to treat a patient based on departmental protocol. The measured doses were compared to those of the treatment planning system. The discrepancies between measured doses and their corresponding calculated doses obtained with the treatment planning system ranged from -29.67 to 40.34% (mean of ±13.27%). These compared similarly to other studies.
Rocznik
Strony
243--250
Opis fizyczny
Bibliogr. 21 poz., rys., tab.
Twórcy
  • Department of Medical Physics, Graduate School of Nuclear and Allied Sciences, University of Ghana, Accra, Ghana
  • Department of Medical Physics, Graduate School of Nuclear and Allied Sciences, University of Ghana, Accra, Ghana
  • Radiation Protection Institute, Ghana Atomic Energy Commission, Accra, Ghana
  • Department of Medical Physics, Graduate School of Nuclear and Allied Sciences, University of Ghana, Accra, Ghana
  • Department of Radiotherapy, National Centre for Radiotherapy and Nuclear Medicine, Korle-Bu Teaching Hospital, Accra, Ghana
  • Department of Medical Physics, Graduate School of Nuclear and Allied Sciences, University of Ghana, Accra, Ghana
autor
  • Department of Radiotherapy, National Centre for Radiotherapy and Nuclear Medicine, Korle-Bu Teaching Hospital, Accra, Ghana
  • Department of Medical Physics, Graduate School of Nuclear and Allied Sciences, University of Ghana, Accra, Ghana
Bibliografia
  • 1. Wilkinson JM, Harris MA, Davidson SE, et al. A retrospective study of bladder morbidity in patients receiving intracavitary brachytherapy as all or part of their treatment for cervix cancer. Br J Radiol. 2003;76:897–903.
  • 2. Garbaulet A, Porter R, Mazeron JJ, et al. The GEC ESTRO Handbook of Brachytherapy. 2002;20:473-480.
  • 3. Viswanathan AN, Thomadsen B. American Brachytherapy Society concensus guidelines for locally advanced carcinoma of the cervix. Part I: General principles. Brachytherapy. 2012;11(1): 33-46.
  • 4. De Leeuw AA, Moerland MA, Nomden C, et al. Applicator reconstruction and applicator shifts in 3D MR-based PDR brachytherapy of cervical cancer. Radiother. Oncol. 2009;93:341–346.
  • 5. Kertzscher G, Rosenfield A, Beddar S, et al. In vivo dosimetry: Trends and prospects for radiotherapy. Br J Radiol. 2014;87(1041):201-206.
  • 6. International Atomic Energy Agency TRS 398 protocol. Implementation of the international code of practice on dosimetry in radiotherapy (TRS 398): Review of testing results. IAEA-TECDOC, 2010:978-92-0-100610-3.
  • 7. Shima K, Tateoka K, Saitoh Y, et al. Analysis of post-exposure density growth in radiochromic film with respect to the radiation dose. J Radiat Res, 2012;53(2):301-305.
  • 8. Saur S, Frengen J. Gafchromic EBT film dosimetry with flatbed CCD scanner: a novel background correction method and full dose uncertainty analysis. Medical Physics, (2008); 35(7):3094–3101.
  • 9. van Battum LJ, Hoffmans D, Piersma H, et al. Accurate dosimetry with GafChromic EBT film of a 6 MV photon beam in water: what level is achievable? Medical Physics, (2008);35(2): 704–716.
  • 10. Karsch L, Beyreuther E, Burris-Mog T, et al. Dose rate dependence for different dosimeters and detectors. Med. Phys. 2012;39(5):2447-2455.
  • 11. Carrara M, Romanyukha A, Tenconi C, et al. Clinical application of MOSkin dosimeters to rectal wall in vivo dosimetry in gynecological HDR brachytherapy. Physica Medica: European Journal of Medical Physics. 2017;41:5–12.
  • 12. Kertzscher G, Andersen CE, Siebert FA, et al. Identifying afterloading PDR and HDR brachytherapy errors using real-time fibrecoupled Al2O3:C dosimetry and a novel statistical error decision criterion. Radiother. Oncol. 2011;100:456–462.
  • 13. Tanderup K, Beddar S, Andersen CE, et al. In vivo dosimetry in brachytherapy. Medical Physics, 2013;40(7):070902-15.
  • 14. Milickovic N, Mavroidis P, Tselis N, et al. 4D analysis of influence of patient movement and anatomy alteration on the quality of 3D U/S-based prostate HDR brachytherapy treatment delivery. Med. Phys. 2011;38:4982–4993.
  • 15. Reniers B, Landry G, Eichner R, et al. In vivo dosimetry for gynaecological brachytherapy using a novel position sensitive radiation detector: Feasibility study. Med. Phys. 2012;39:1925–1935.
  • 16. Kutcher GJL, Coia M, Gillin WF, et al. Comprehensive QA for radiation oncology: Report of AAPM Radiation Therapy Committee Task Group 40. Med. Phys. 1994;21(4):581-61.
  • 17. Allahverdi M, Sarkhosh M, Aghili M, et al. Evaluation of treatment planning system of brachytherapy according to dose to the rectum delivered. Radiat. Prot. Dosim. 2012;150:312–315.
  • 18. Seymour EL, Downes SJ, Fogarty GB, et al. In vivo real-time dosimetric verification in high dose rate prostate brachytherapy,” Med. Phys. 2011;38:4785–4794.
  • 19. Waldhäusl C, Wambersie A, Potter R, and Georg D. In-vivo dosimetry for gynaecological brachytherapy: Physical and clinical considerations. Radiother. Oncol. 2005;77:310–317.
  • 20. Chao KS, Perez CA, Brady LW. Physics and Dosimetry of High-Dose-Rate Brachytherapy in Radiation Oncology Management Decisions (2nd Edition). Lippincott Williams & Wilkins. Philadelphia. 2002;89–94.
  • 21. Ballester F, Granero D, Perez-Calatyud J, Casal E, Agramunt S, Cases R. Monte Carlo dosimetric study of the BEBIG Co-60 HDR source. Phys Med Biol. 2005;50:N309–16.
Uwagi
Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2021).
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-7f33bc3e-fc79-47fd-8e73-fbcaf54b5083
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