Drosophila melanogaster as a model organism for nanoparticle toxicity research

• Autorzy: Łakomy Weronika , Myślińska Maria , Tarnawska Ewa , Kulig Karolina , Owczarzy Aleksandra , Rogóż Wojciech , Maciążek-Jurczyk Małgorzata

Identyfikatory

DOI

https://doi.org/10.34821/eng.biomat.173.2025.02

• Języki publikacji: EN

Abstrakty

EN

Nanotechnology is a rapidly developing interdisciplinary field that combines branches of science such as engineering, physics, chemistry, biology, computer science, biotechnology, medicine, and pharmacy. Due to the rapid growth of interest in nanotechnology, new methods are needed to study the effects of nanoparticles on living organisms. In combination with in vitro and in vivo studies on vertebrate animals, valuable research data can be obtained through in vivo studies on invertebrates. Drosophila melanogaster (D. melanogaster), widely known as the fruit fly, has long been a cornerstone of genetic and developmental biology research. Its popularity owes to the short life cycle and approximately 13,600 genes, many of which are homologous to human genes. In recent years, the use of D. melanogaster has also been extended to the rapidly growing scientific field of nanotechnology. As a model organism, D. melanogaster offers a unique combination of genetic tractability and conservativeness of biological pathways, making it an ideal candidate for studying the biological impacts of nanoparticles. This article discusses the types of nanoparticles as a drug delivery system, one of their classifications, and use in pharmacy. It also reviews the growing role of D. melanogaster in nanoparticle research, highlighting its potential to provide insights mainly into nanoparticle toxicity, biodistribution, and therapeutic applications.

Słowa kluczowe

EN

nanotechnology; Drosophila melanogaster; nanoparticles; toxicity; model organism

PL

nanotechnologia; toksyczność; model

• Wydawca: Polish Society for Biomaterials in Cracow
• Czasopismo: Engineering of Biomaterials
• Rocznik: 2025
• Tom: vol. 28, no. 173
• Strony: art. no. 2
• Opis fizyczny: Bibliogr. 49 poz., rys., tab.

Twórcy

autor

Łakomy Weronika

• Student Research Group at the Department of Physical Pharmacy, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 15 Poniatowskiego St., 40-055 Katowice, Poland

autor

Myślińska Maria

• Student Research Group at the Department of Physical Pharmacy, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 15 Poniatowskiego St., 40-055 Katowice, Poland

autor

Tarnawska Ewa

• Student Research Group at the Department of Physical Pharmacy, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 15 Poniatowskiego St., 40-055 Katowice, Poland

autor

Kulig Karolina

• Department of Physical Pharmacy, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 15 Poniatowskiego St., 40-055 Katowice, Poland

autor

Owczarzy Aleksandra

• Department of Physical Pharmacy, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 15 Poniatowskiego St., 40-055 Katowice, Poland

autor

Rogóż Wojciech

• Department of Physical Pharmacy, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 15 Poniatowskiego St., 40-055 Katowice, Poland

autor

Maciążek-Jurczyk Małgorzata

• Department of Physical Pharmacy, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 15 Poniatowskiego St., 40-055 Katowice, Poland

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa nr POPUL/SP/0154/2024/02 w ramach programu "Społeczna odpowiedzialność nauki II" - moduł: Popularyzacja nauki i promocja sportu (2025).