The influence of sterilization on properties of polyurethane/polylactide blend

• Autorzy: Bednarz P. , Bernasik A. , Laska J.

Identyfikatory

DOI

10.5604/01.3001.0012.1264

• Języki publikacji: EN

Abstrakty

EN

The biodegradable polyurethane/polylactide blend was treated with low temperature hydrogen peroxide plasma, ethylene oxide and immersing in ethanol combined with ultraviolet radiation. The samples sterilized by hydrogen peroxide and ethylene oxide stood practically unaffected, while UV/EtOH caused distinct changes in their mechanical properties. For example the significant reduction of tensile strength occurred, elongation at break became twice lower, while the Young’s modulus increased by 23%. The XPS measurements showed that after all types of treatment atomic carbon and nitrogen concentrations in the surface layer was slightly lower than in the bulk. Instead the surface layer was more enriched with oxygen. Ethylene oxide sterilization caused that both surfaces became more hydrophobic i.e. the contact angle increased about 15% for the top surface and 8% for the bottom surface, respectively. Sterilization with ethanol and UV radiation changed the nature of surface into more hydrophilic, the contact angle of the top surface was reduced about 6% and the bottom about 24%. The FT-IR spectra of all sterilized samples were recorded and discussed. From all used sterilization methods only hydrogen peroxide plasma is fully suitable for biodegradable PU/PLA blend.

Słowa kluczowe

EN

sterilization; surface; biodegradable polymer; topography; morphology

PL

sterylizacja; powierzchnia; biodegradowalny polimer; topografia; morfologia

• Wydawca: Państwowa Wyższa Szkoła Zawodowa w Tarnowie
• Czasopismo: Science, Technology and Innovation
• Rocznik: 2018
• Tom: Vol. 2, no. 1
• Strony: 13--18
• Opis fizyczny: Bibliogr. 22 poz., rys., tab.

Twórcy

autor

Bednarz P.

• State Higher Vocational School in Tarnów, Mickiewicza 8, 33-100 Tarnów, Poland

autor

Bernasik A.

• AGH University of Science and Technology, Academic Centre for Materials and Nanotechnology, 30 Mickiewicza Av., 30-059 Krakow, Poland

autor

Laska J.

• AGH University of Science and Technology, Faculty of Materials Science and Ceramics, 30 Mickiewicza Av., 30-059 Krakow, Poland

Bibliografia

• 1. Gorna K, Gogolewski S, Mainili Varlet P. The effect of thermal treatment on sterility, molecular and mechanical properties of various polylactides. 2. Poly(L/D – lactide) and poly(L/DL – lactide). Biomaterials 1997; 18:251-255.
• 2. Kyriacos A.A., Niederauer G.G., Agrawal C.M. Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers. Biomaterials 1996;17: 93-102.
• 3. Edlund U, Albertsson A.C., Singh S.K., Fogelberg B.O., Lundgren I. Sterilization, storage stability and in vivo biocompatibility of poly(trimethylene carbonate)/poly(adipic anhydride) blends. Biomaterials 2000; 21(9):945–955.
• 4. da Silva Aquino K.A., Adrovic F, editor. Sterilization by Gamma Irradiation. Gamma Radiation. In Tech, 2012.
• 5. Henn G.G., Birkinshaw C, Buggy M.A. Comparison of the effects of γ-irradiation and ethylene oxide sterilization on the properties of compression moulded poly-d,l-lactide. J Mater Sci: Mater Med 1996;7:591–595.
• 6. Henn G.G., Birkinshaw C, Buggy M, Jones E. Evaluation of poly-DL-lactide bio-absorbable intramedullary plugs. Polym Degrad Stab 1998;61:375-82
• 7. Nugroho P, Mitomo H, Yoshii F, Kume T. Degradation of poly (l-lactic acid) by γ-irradiation. Polym Degrad Stab 2001;72:337–343.
• 8. Hooper K, Cox D, Kohn J. Comparison of the effect of ethylene oxide and γ-irradiation on selected tyrosine-derived polycarbonates and poly(l-lactic acid). J Appl Polym Sci 1997;63: 1499–1510.
• 9. Gogolewski S, Mainili-Varlet P. The effect of thermal treatment on sterility, molecular and mechanical properties of various polylactides. Biomaterials 1996; 17:523-528.
• 10. Moreira A.J., Mansano R.D., de Jesus Andreoli Pinto T, Ruas R, da Silva Zambon L, Valero da Silva M, Verdonck P.B. Sterilization by oxygen plasma. App. Surf. Sci. 2004; 235(1–2):151–155.
• 11. Mendes G.C.C., Brandão T.R.S., Silva C.L.M. Ethylene oxide sterilization of medical devices: A review. Am. J. Infection Control 2007; 35(9):574–581.
• 12. Moisan M, Barbeau J, Crevier M.C., Pelletier J, Philip N, Saoudi B. Plasma sterilization. Methods and mechanisms. Pure Appl. Chem. 2002;74(3):349-358.
• 13. Lerouge S, Wertheimer M.R., Marchard R, Tabrizian M, Yahia L.H. Effect of gas composition on spore moratlity and etching during low-pressure plasma sterilization. J. Biomedical Mater. Res. 2000;51(1):128–135.
• 14. Lerouge S, Wertheimer M.R., Yahia L.H. Plasma Sterilization: A review of parameters mechanism and limitation. Plasmas and Polymers. 2001;6(3):175-188.
• 15. Moisan M, Barbeau J, Moreau S, Pelletier J, Tabrizian M & Yahia, L. Low-temperature sterilization using gas plasmas: a review of the experiments and an analysis of the inactivation mechanisms. Inter. J. Pharmaceutics. 2001; 226(1): 1-21.
• 16. Gogolewski S, Mainil-Varlet P, Dillon J. Sterility, mechanical properties, and molecular stability of polilactide internal-fixation devices treated with low-temperature plasmas. J. Biomed Mater Res 1996;32:227-235.
• 17. Bor Y, Alin J, Hakkarainen M. Electrospray ionization-mass spectrometry analysis reveals migration of cyclic lactide oligomers from polylactide packaging in contact with ethanolic food simulant. Packaging Tech. & Sci. 2012; 25(7): 427-433.
• 18. Peniston S.J., Choi S.J. Effect of sterilization on the physicochemical properties of molded poly(L-lactic acid). J Biomed Mater Res B Appl Biomater. 2007; 80(1):67-77.
• 19. Hans J, Griesser R.C., Chatelieb T.R., Gengenbach G.J., Steele J.G. Growth of human cells on plasma polymers: Putative role of amine and amide groups. J. Biomater. Sci. Polymer Edition 1994; 5(6):531-554.
• 20. Anderws K.D., Kunt J.A., Black R.A. Effects of sterilization method on surface topography and in vitro cell behaviour of electrostatically spun scaffolds. Biomater. 2007; 28:1014-1026
• 21. Gorna K, Gogolewski S. In vitro degradation of novel medical biodegradable aliphatic polyurethanes based on ε-caprolactone and Pluronics® with various hydrophilicities. Polym. Degrad. Stab. 2002; 75:113-122
• 22. Pamuła E, Błażewicz M, Paluszkiewicz C, Dobrzyński P. FTIR study of degradation products of aliphatic polyesters – carbon fibres composites, J. Mol. Structure 2001; 596: 69-75.

Uwagi

Opracowanie rekordu w ramach umowy 509/P-DUN/2018 ze środków MNiSW przeznaczonych na działalność upowszechniającą naukę (2019).