Powiadomienia systemowe
- Sesja wygasła!
- Sesja wygasła!
- Sesja wygasła!
- Sesja wygasła!
Tytuł artykułu
Autorzy
Wybrane pełne teksty z tego czasopisma
Identyfikatory
Warianty tytułu
Języki publikacji
Abstrakty
Purpose: One of the major problems in bone surgery are infections – especially those occurring in the course of the operating on the patients with lowered immunity system, because they carry the danger of complications. In the Mechanical Department of Technical University of Gdansk, there has been carried the research with the use of bone cement and metal nanoparticles. Design/methodology/approach: The bone cement was used without supplement or with one or two drugs. These experiments are the latest, because include pure bone cement (without drugs) with nanometals. The titanium specimens was covering with such compose coating. The implant was inserted into rat`s thigh for six weeks. Afterwards the implant was removed from the body and examined by means of scanning electron microscope. Simultanously biological research was carried out. Bonless samples were placed into bacterial liquid, generated by the researcher (the Patent number P 409082 ) containing five most frequently occurring bacteria in human body. Findings: Result of the SEM research was positive – there was good adhesion of ostheoblasts to the surface and there were no traces of infection. Practical implications: The research concerns bone cement with nanoparticles proves, that nanoparticles are the alternatives to antibiotics.
Słowa kluczowe
Wydawca
Rocznik
Tom
Strony
15--21
Opis fizyczny
Bibliogr. 30 poz., rys., tab.
Twórcy
autor
- Mechanical Faculty, Gdansk University of Technology, ul. Narutowicza 11/12, 80-233 Gdańsk, Poland
Bibliografia
- [1] S. Saska, L.S. Mendes, A.M.M. Gaspar, T. Capote, Chapter 2: Bone substitute materials in implant dentistry, in: Current Concepts in Dental Implantology, Ed. I. Turkyilmaz, Intech,2015, http://dx.doi.org/10.5772/59487.
- [2] P. Li, Biomimetic nano-apatite coating capable of promoting bone ingrowth, Journal of Biomedical Materials Research A 66 (2003) 79-85.
- [3] R.J. Vance, D.C. Miller, A. Thapa, K.M. Haberstroh, T.J. Webster, Decreased fibroblast cell density on chemically degraded poly-lactic-co-glycolic acid, polyurethane, and polycaprolactone, Biomaterials 25 (2004) 2095-2103.
- [4] H. Liu, T.J. Webster, Nanomedicine for implants: a revive of studies and necessary experimental tools, Biomaterials 28 (2007) 354-369.
- [5] E.S. Kovaleva, A.V. Kiznetsov, A.V. Soin, A.G. Veresov, V.I. Putlyaev, Y.D. Tret`Yakov, Study of materials bioactivity of the use of model media, Doklady Chemistry 405 (2005) 213-216.
- [6] C.E. Misch, Contemporary implant dentistry, 2nd Edition, St Louis, Mosby, 2006.
- [7] S. Saska, H.S. Barud, A.M.M. Gaspar, R. Marchetto, S.J.L. Ribeiro, Y. Messaddeq, Bacterial cellulosehudroxyapatite nanocomposites for bone regeneration, International Journal of Biomaterials 2011 (2011), doi:10.1155/2011/175362.
- [8] K.A. Hing, L.F. Wilson, T. Buckland, Comparative performance of three ceramic bone graft substitutes, The Spine Journal 7 (2007) 475-490.
- [9] L. Polo-Corrales, M. Latorre-Esteves, J.E. RamirezVick, Scaffold design for bone regeneration, Journal of Nanoscience and Nanotechnology 14 (2014) 15-56.
- [10] R. Langer, J.P. Vacanti, Tissue engineering, Science 260 (1993) 920-926.
- [11] V.A. Dubok, Bioceramics – Yesterday, today, tomorrow, Powder Metallurgy and Metal Ceramics 39 (2000) 381-394.
- [12] L.L. Hench, The story of Bioglass, Journal of Materials Science. Materials in medicine 17 (2006) 967-978.
- [13] V. Krishnan, T. Lakshmi, Bioglass: A novel biocompatible innovation, Journal of Advanced Pharmaceutical Technology & Research 4 (2013) 7883.
- [14] M. Klein, C. Glatzer, Individual CAD/CAM fabricated glass-bioceramic implants in reconstructive surgery of the bony orbital floor, Plastic and Reconstructive Surgery 17 (2006) 565-570.
- [15] L. Li, C.Y. Bao, G.M. Ou, W.C. Chen, X.J. Zhang, D.Y. Yang, Q. Wang, L.Y. Sun, C.D. Xiong, Guiding bone regeneration with a novel biodegradable polymeric membrane and bioceramic bone grafts around dental implants, Key Engineering Materials 330-332 (2007) 1417-1420.
- [16] R.E. Marx, Applications of tissue engineering: Principles to clinical practice, Chicago Publishing Co, 2008, 47-63.
- [17] B.T. Estes, J.M. Gimble, F. Guilak, Mechanical signals as regulators of stem cell fate, Current Topics in Developmental Biology 60 (2004) 91-126.
- [18] V. Karageorgiou, D. Kaplan, Porosity of 3D biomaterial scaffolds and osteogenesis, Biomaterials 26 (2005) 5474-5491.
- [19] S. Park, G. Kim, Y.C. Jeon, Y. Koh, W. Kim, 3D polycaprolacton scaffolds with controlled pore structure Rusing a rapid prototyping system, Journal of Materials Science: Materials in Medicine 20 (2009) 229-234.
- [20] S. Bose, S. Vahabzadeh, A. Bandyopadhyay, Bone tissue engineering using 3D printing, Materials Today 16 (2013) 496-504.
- [21] S. Perni, V. Thenault, P. Abdo, K. Margulis, S. Magdassi, P. Prokopovich, Antimicrobal activityof bone cements embedded with organic nanoparticles, International Journal of Medicine 10 (2015) 6317-6329.
- [22] D. Regis, A. Sandri, E. Samaila, A. Benini, M. Bondi, B. Magnan, Release of Gentamicin and Vancomicin from performed spacers in infected total hip artroplasties: measurement of concentrations and inhibitory activity in patients` drainage fluids and serum, The Scientific World Journal 2013 (2013), http://dx.doi.org/10.1155/2013/752184.
- [23] A.G. Valle, M. Bostrom, B. Brause, C. Harney, E.A. Salvati, Effective bactericidal activity of tobramycin and vancomycin eluted from acrylic bone cement, Acta Orthopaedica Scandinavica 72/3 (2001) 237-240.
- [24] S.L. Henry, K.P. Galloway, Local antibacterial therapy for the management of orthopaedic infections: pharmacokinetic considerations, Clinical Pharmacokinetics 29/1 (1995) 36-45.
- [25] K. Anagnostakos, P. Wilmes, E. Schmitt, J. Kelm, Elution of gentamicin and vancomycin from polymethylmethacrylate beads and hip spacers in vivo, Acta Orthopaedica 80/2 (2009) 193-197.
- [26] E. Bertazzoni, A. Benini, B. Magnan, P. Bartolozzi, Release of gentamicin and vancomycin from temporary human hip spacers in two- stage revision of infected arthroplasty, Journal of Antimicrobal Chemotherapy 53/2 (2004) 329-334.
- [27] C.M. Keck, K. Schwabe, Silver-nanolipid complex for application to atopic dermatitis skin: rheological characterization, in vivo efficiency and theory of action, Journal of Biomedical Nanotechnology 5/4 (2009) 428-436.
- [28] The bone cement was obtained from Higmed Poland sc, the only distributer of the Tecres Company products.
- [29] P. Karasiński, E. Gondek, S. Drewniak, A. Kajzer, N. Waczyńska-Niemiec, M. Basiaga, W. Izydorczyk, Y.E.L. Kouarie, Porous titania films fabricated via sol gel rout – optical and AFM characterization, Optical Materials 56 (2016) 64-70.
- [30] D.R.P. Neumann, T. Hofstaedter, C. List, U. Dorn, Two-stage cementless revision of late total hip arthoplasty infection using a premanufactured spacer, Journal of Arthroplasty 27/7 (2012) 1397-1401.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-6ec10a28-6d2e-4c89-b6a3-e48080f46b99