Separation and quantification of nine bioactive compounds in traditional Unani formulations by High Performance Liquid Chromatography–Photodiode Array Detector

• Autorzy: Kamal Y. T. , Ahmad Sayeed , Mahadevan Nanjaian , Alam Prawez , Salam Shahana , Asiri Yahya , Muhsinah Abdullatif Bin , Alsayari Abdulrhman

Identyfikatory

DOI

10.1556/1326.2020.00696

• Języki publikacji: EN

Abstrakty

EN

A new High Performance Liquid Chromatography–Photodiode Array Detector (HPLC–PDA) method has been developed for the chromatographic separation and simultaneous quantitative determination of nine bioactive compounds, i.e. four phenolic (gallic acid, ellagic acid, chebulinic acid, and tannic acid), two flavanoids (rutin and quercetin), two anthraquinones (sennoside A and B) and one oxygenated hydrocarbon (vitamin C) in a well-known Unani polyherbal formulation namely Itrifal’s. Separation was accomplished on a C18 LiChrospher 100 column (5 mm, 250 3 4.6 mm) with a gradient elution and recorded at 254 nm. The results demonstrated that the proposed method is reproducible, accurate, economic, and suitable for the quality control of traditional polyherbal Unani formulations containing complex compounds with different structures such as Itrifals.

Słowa kluczowe

EN

HPLC-PDA; quality control; polyherbal formulation; simultaneous determination

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2021
• Tom: Vol. 33, no. 1
• Strony: 3--10
• Opis fizyczny: Bibliogr. 21 poz., rys., tab.

Twórcy

autor

Kamal Y. T.

• Department of Pharmacognosy, College of Pharmacy, King Khalid University, 61441, Abha, Kingdom of Saudi Arabia

• https://orcid.org/0000-0002-4064-8544

autor

Ahmad Sayeed

• Department of Pharmacognosy and Phytochemistry, Bioactive Natural Product Laboratory, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India

autor

Mahadevan Nanjaian

• Department of Pharmacognosy, College of Pharmacy, King Khalid University, 61441, Abha, Kingdom of Saudi Arabia

autor

Alam Prawez

• Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, P.O. Box 173, 11942, Al-Kharj, Kingdom of Saudi Arabia

autor

Salam Shahana

• Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, P.O. Box 173, 11942, Al-Kharj, Kingdom of Saudi Arabia

autor

Asiri Yahya

• Department of Pharmacology, College of Pharmacy, King Khalid University, 61441, Abha, Kingdom of Saudi Arabia

autor

Muhsinah Abdullatif Bin

• Department of Pharmacognosy, College of Pharmacy, King Khalid University, 61441, Abha, Kingdom of Saudi Arabia

autor

Alsayari Abdulrhman

• Department of Pharmacognosy, College of Pharmacy, King Khalid University, 61441, Abha, Kingdom of Saudi Arabia

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2021).