Effect of simulated body fluid on the microstructure of melt spun composite fibers

• Autorzy: Rajzer I. , Rom M. , Fabia J. , Sarna E. , Biniaś D. , Zima A. , Ślósarczyk A. , Janicki J.
• Języki publikacji: EN

Abstrakty

EN

Polylactic acid (PLA) offers unique features of biodegradability and thermal processability, that offer potential applications in medicine. PLA can be transformed into fibers by spinning enabling then subsequent fabrication of desirable three dimensional fabrics which may be used as scaffolds for tissue engineering applications. Incorporation of synthetic nano-hydroxyapatite into the fibrous polymer matrix can enhance bioactive properties of the prospective scaffold. In the present work, the method of production of composite fibers based on polylactic acid (PLA) and nano-hydroxyapatite (n-HAp) is proposed. Obtained fibers have shown excellent apatite-forming ability when immersed in simulated body fluid.

Słowa kluczowe

EN

composites fibers; simulated body fluid; polylactic acid; hydroxyapatite; bone tissue regeneration

• Wydawca: Polish Society for Biomaterials in Cracow
• Czasopismo: Engineering of Biomaterials
• Rocznik: 2009
• Tom: Vol. 12, no. 88
• Strony: 2--4
• Opis fizyczny: Bibliogr. 8 poz., wykr., zdj.

Twórcy

autor

Rajzer I.

• ATH University of Bielsko-Biala, Faculty of Materials and Environmental Sciences, Institute of Textile Engineering and Polymer Science, Department of Polymer Materials, 2 Willowa, 43-309 Bielsko-Biala, Poland

autor

Rom M.

• ATH University of Bielsko-Biala, Faculty of Materials and Environmental Sciences, Institute of Textile Engineering and Polymer Science, Department of Polymer Materials, 2 Willowa, 43-309 Bielsko-Biala, Poland

autor

Fabia J.

• ATH University of Bielsko-Biala, Faculty of Materials and Environmental Sciences, Institute of Textile Engineering and Polymer Science, Department of Polymer Materials, 2 Willowa, 43-309 Bielsko-Biala, Poland

autor

Sarna E.

• ATH University of Bielsko-Biala, Faculty of Materials and Environmental Sciences, Institute of Textile Engineering and Polymer Science, Department of Polymer Materials, 2 Willowa, 43-309 Bielsko-Biala, Poland

autor

Biniaś D.

• ATH University of Bielsko-Biala, Faculty of Materials and Environmental Sciences, Institute of Textile Engineering and Polymer Science, Department of Polymer Materials, 2 Willowa, 43-309 Bielsko-Biala, Poland

autor

Zima A.

• AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Technology of Ceramics and Refractories, al. Mickiewicza 30, 30-059 Krakow, Poland

autor

Ślósarczyk A.

• AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Technology of Ceramics and Refractories, al. Mickiewicza 30, 30-059 Krakow, Poland

autor

Janicki J.

• ATH University of Bielsko-Biala, Faculty of Materials and Environmental Sciences, Institute of Textile Engineering and Polymer Science, Department of Polymer Materials, 2 Willowa, 43-309 Bielsko-Biala, Poland

Bibliografia

• [1] Yuan X et al. Characterization of poly (L-lactic acid) fibers produced by melt spinning. Journal of Applied Polymer Science 2001; 81, 251-60.
• [2] F. Barre`re et al. Advanced biomaterials for skeletal tissue regeneration: Instructive and smart functions. Materials Science and Engineering 2008; R 59: 38–71.
• [3] Gupta B, Revagade N, Hiborn J. Poly(lactic acid) fiber: An overview. Progress in Polymer Science 2007; 32: 455-482.
• [4] M.Navarro et al. In vitro degradation behavior of a novel bioresorbable composite material based on PLA and soluble CaP glass. Acta Biomaterialia 2005; 1: 411-419.
• [5] Jose MV et al. Aligned PLGA/HA nanofibrous nanocomposite scaffolds for bone tissue engineering. Acta Biomaterialia 2009; 5: 305-315.
• [6] Kalita S.J. et al. Nanocrystalline calcium phosphate ceramics in biomedical engineering. Materials Science and Engineering 2007; C 27: 441–449.
• [7] Kasuga T et al. Preparation of poly(lactic acid) composites containing calcium carbonate (vaterite). Biomaterials 2003; 24: 3247-3253.
• [8] Kokubo T et al. How useful is SBF in predicting in vivo bone bioactivity? Biomaterials 2006; 27 (15): 2907-2915