Analytical control of diclofenac removal in the photocatalytic oxidation process

• Autorzy: Bohdziewicz J. , Kudlek-Jelonek E. , Dudziak M.
• Języki publikacji: EN

Abstrakty

EN

The increasing consumption of drugs results in a continuous release of these chemicals and their metabolites in the aqueous environment, which is at the level of a few ng/dm3 to several μg/dm3. Particular attention should be paid to the group of medicines which are available without prescription which include non-steroidal painkillers and anti-inflammatory drugs. The paper presents the possibility of the analytical control of diclofenac photocatalytic oxidation process in the aquatic environment. To examine the effectiveness of the process the HPLC analysis preceded with solid phase extraction SPE, measurements of UV absorbance and total organic carbon were used. The chromatographic measurements revealed the higher sensitivity than the UV absorbance measurements (λ = 276 nm). On the other hand, the total organic carbon analysis showed that the degradation of the removed compound was incomplete and by-products were formed during the process.

PL

Stale rosnąca konsumpcja farmaceutyków przyczynia się do zwiększenia ich stężenia w środowisku wodnym, które kształtuje się w zakresie od kilku ng/dm3 do kilku μg/dm3. Liczną grupę wśród farmaceutyków występujących w wodach powierzchniowych stanowią niesteroidowe leki przeciwbólowe i przeciwzapalne, do których należy m.in. diklofenak. W pracy przedstawiono możliwości kontroli analitycznej procesu fotokatalitycznego utleniania diklofenaku w środowisku wodnym. Do badania skuteczności procesu zastosowano analizę HPLC poprzedzoną ekstrakcją do fazy stałej oraz pomiar absorbancji w UV (λ=276 nm) i ogólnego węgla organicznego. W celu określenia stężenia usuwanego związku przydatna okazała się analiza chromatograficzna, z którą w dobrym stopniu korespondowały wyniki pomiarów absorbancji w UV. Dowiedziono, że pomiar chromatograficzny charakteryzuje się większą czułością niż pomiar absorbancji wody. Na podstawie pomiarów ogólnego węgla.

Słowa kluczowe

EN

diclofenac; photocatalysis; SPE; HPLC; absorbance in UV; total organic carbon (TOC)

PL

diklofenak; fotokataliza; SPE; HPLC; absorbancja w UV; ogólny węgiel organiczny

• Wydawca: Silesian University of Technology
• Czasopismo: Architecture Civil Engineering Environment
• Rocznik: 2013
• Tom: Vol. 6, no. 3
• Strony: 71--75
• Opis fizyczny: Bibliogr. 17 poz.

Twórcy

autor

Bohdziewicz J.

• Faculty of Energy and Environmental Engineering, The Silesian University of Technology, Konarskiego 18, 44-100 Gliwice, Poland

autor

Kudlek-Jelonek E.

• Faculty of Energy and Environmental Engineering, The Silesian University of Technology, Konarskiego 18, 44-100 Gliwice, Poland

autor

Dudziak M.

• Faculty of Energy and Environmental Engineering, The Silesian University of Technology, Konarskiego 18, 44-100 Gliwice, Poland

Bibliografia

• [1] Nawrocki J.; Uzdatnianie wody : procesy fizyczne, chemiczne i biologiczne (Water treatment: physical, chemical and biological processes), Część 1, Warszawa, Wydawnictwo Naukowe PWN 2010 (in Polish).
• [2] Snyder S.A., Westerhoff P., Yoon Y., Sedlak D.L.; Pharmaceuticals, personal care products, and endocrine disruptors in water: implications for the water industry. Environmental Engineering Science, Vol.20, No.5, 2003; p.449-469.
• [3] Kumar A., Xagoraraki I.; Pharmaceuticals, personal care products and endocrine-disrupting chemicals in U.S. surface and finished drinking waters: A proposed ranking system. Science of the Total Environment. Vol.408, No.23, 2010; p.5972-5989.
• [4] Buntner D., Żabczyński S., Miksch K.; Usuwanie farmaceutyków ze ścieków (Removal of pharmaceuticals from wastewater). Chemik, Vol.60, No.2, 2007; p.120-124. (in Polish).
• [5] Ternes, T.A., Bonerz, M., Hermann, N., Teiser, B., Andersen, H. R.; Irrigation of treated wastewater in Braunschweig, Germany: an option to remove pharmaceuticals and musk fragrances. Chemosphere, Vol.66, No.5, 2007; p.894-904.
• [6] Carlsson C., Johansson A.-K., Alvan G., Bergman K., Kuhler T.; Are pharmaceuticals potent environmental pollutants? Part I: Environmental risk assessments of selected active pharmaceutical ingredients. Science of the Total Environment Vol.364, No.1-3, 2006; p. 7-87.
• [7] Fent K., Weston A. A., Caminada D.; Ecotoxicology of human pharmaceuticals. Aquatic Toxicology, Vol.76, No.2, 2006; p.122-159.
• [8] Schröder H. Fr., Tambosi J. L., Sena R. F., Moreira R. F. P. M., José H. J., Pinnekamp J.; The removal and degradation of pharmaceutical compounds during membrane bioreactor treatment. Water Science and Technology, Vol.65, No.5, 2012, p.833-839.
• [9] Behera S.K., Kim H.W., Oh J.-E., Park H.-S.; Occurrence and removal of antibiotics, hormones and several other pharmaceuticals in wastewater treatment plants of the largest industrial city of Korea. Science of the Total Environment, Vol.409, No.20, 2011; p.4351-4360.
• [10] Matamoros V., Arias C., Brix H., Bayona J.M;, Preliminary screening of small-scale domestic wastewater treatment systems for removal of pharmaceutical and personal care products. Water Research, Vol.43, No.1, 2009; p.55-62.
• [11] Radjenovic J., Petrovic M., Ventura F., Barcelo D.; Rejection of pharmaceuticals in nanofiltration and reverse osmosis membrane drinking water treatment. Water Research, Vol.42, No.14, 2008; p.3601-3610.
• [12] Aguinaco A., Beltrán F.J., García-Araya J.F., Oropesa A.; Photocatalytic ozonation to remove the pharmaceutical diclofenac from water: Influence of variables. Chemical Engineering Journal, Vol.189-190 No.0, 2012; p.275-282.
• [13] Chatzitakis A, Berberidou C, Paspaltsis I, Kyriakou G, Sklaviadis T, Poulios I.; Photocatalytic degradation and drug activity reduction of chloramphenicol. Water Research, Vol.42, No.1-2, 2008; p.386-394.
• [14] Doll T.E, Frimmel F.H.; Kinetic study of photocatalytic degradation of carbamazepine, clofibric acid, iomeprol and iopromide assisted by different TiO2 materials determination of intermediates and reaction pathways. Water Research, Vol.38, No.4, 2004; p.955-964.
• [15] Miró P., Arques A., Amat A.M., Marin M.L., Miranda M.A.; A mechanistic study on the oxidative photodegradation of 2.6-dichlorodiphenylamine-derived drugs: Photo-Fenton versus photocatalysis with a triphenylpyrylium salt. Applied Catalysis B: Environmental, Vol.140-141, 2013; p.412-418.
• [16] Salgado R., Pereira V.J., Carvalho G., Soeiro R., Gaffney V., Almeida C., Vale Cardoso V., Ferreira E., Benoliel M.J., Ternes T.A., Oehmen A., Reis M.A.M., Noronha J.P.; Photodegradation kinetics and transformation products of ketoprofen, diclofenac and atenolol in pure water and treated wastewater. Journal of Hazardous Materials, Vol.244-245, 2013; p. 516-527.
• [17] Gurkan Y.Y., Turkten N., Hatipoglu A., Cinar Z.; Photocatalytic degradation of cefazolin over N-doped TiO2 under UV and sunlight irradiation: Prediction of the reaction paths via conceptual DFT. ChemicalEngineering Journal, Vol.184, 2012; p.113-124.