Investigation of the Antioxidant and Anti-Inflammatory Capacities of Different Extracts from Cistus ladanifer L. Leaves in the Ait Ammart Region (Northern Morocco)

• Autorzy: Benamari Omar , Labhar Amina , Ahidar Naoufal , Salhi Amin , Ahari M'hamed , Elyoussfi Abdellah , Benyoub Bouchra , Amhamdi Hassan

Identyfikatory

DOI

10.12912/27197050/179421

• Języki publikacji: EN

Abstrakty

EN

Plants are a significant source for identifying new compounds (particularly secondary metabolites) with medicinal value for drug development, pharmaceuticals, and food additives. Many of these healing plants are frequently used in conventional medicine to treat and prevent various diseases. The purpose of the current research is to assess the total phenolic content (TPC) and total flavonoid content (TFC) for phytochemical analysis, DPPH and FRAP (Ferric Reducing Antioxidant Power) assays for antioxidant activity (AOA), and the activity of reducing inflammation exhibited by various extracts, which were determined by measurement of absorbance with a UV spectrophotometer. The outcome demonstrated that the Cistus ladanifer L leaf aqueous extract (EAqCL) has the highest yield (15.581%) and the highest phenolic content (98.28 ± 0.32 mg GAE/g_ext) compared to the other extracts. Whereas, ethanol extract (EECL) exhibited the highest flavonoid content (11.39 ± 1.45 mg QE/g_ext), DPPH-radical scavenging activity (RSA = 94.534 ± 1.24%) at 800 μg/ml and FRAP (1.017 ± 0.12) at 400 μg/mL. The extract also showed better anti-inflammatory activity (95.61 ± 0.92%) at 1000 μg/ml. According to the results obtained, this sticky shrub growing in the Ait Ammart region has great potential for exploiting natural sources of bioactive substances and producing pharmacologically active metabolites.

Słowa kluczowe

EN

Cistus ladanifer L.; solvent extraction; polyphenols; antioxidant; anti-inflammatory

• Wydawca: Lubelski Oddział Polskiego Towarzystwo Inżynierii Ekologicznej ; Lublin University of Technology ; WNGB Wydawnictwo Naukowe
• Czasopismo: Ecological Engineering & Environmental Technology
• Rocznik: 2024
• Tom: Vol. 25, iss. 3
• Strony: 178--184
• Opis fizyczny: Bibliogr. 26 poz., rys., tab.

Twórcy

autor

Benamari Omar

• Research Unit for Applied Chemistry (URCA), FSTH, Abdelmalek Essaadi University, Tetouan, Morocco

• https://orcid.org/0009-0004-0038-7919

autor

Labhar Amina

• Research Unit for Applied Chemistry (URCA), FSTH, Abdelmalek Essaadi University, Tetouan, Morocco

• https://orcid.org/0000-0003-1015-484X

autor

Ahidar Naoufal

• Research Unit for Applied Chemistry (URCA), FSTH, Abdelmalek Essaadi University, Tetouan, Morocco

• https://orcid.org/0009-0003-6022-5084

autor

Salhi Amin

• Research Unit for Applied Chemistry (URCA), FSTH, Abdelmalek Essaadi University, Tetouan, Morocco

• https://orcid.org/0000-0002-5243-747X

autor

Ahari M'hamed

• Research Unit for Applied Chemistry (URCA), FSTH, Abdelmalek Essaadi University, Tetouan, Morocco

• https://orcid.org/0000-0002-0457-5923

autor

Elyoussfi Abdellah

• Research Unit for Applied Chemistry (URCA), FSTH, Abdelmalek Essaadi University, Tetouan, Morocco

• https://orcid.org/0000-0002-3668-8789

autor

Benyoub Bouchra

• Civil Engineering and Environmental Management Research Team GEGC, LSA, ENSAH, Abdelmalek Essaadi University, Tetouan, Morocco

• https://orcid.org/0009-0008-7751-898X

autor

Amhamdi Hassan

• Research Unit for Applied Chemistry (URCA), FSTH, Abdelmalek Essaadi University, Tetouan, Morocco

• https://orcid.org/0000-0002-6693-5752

Bibliografia

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2024).