Towards high sensitivity and high-resolution PET scanners: imaging-guided proton therapy and total body imaging

• Autorzy: Lang Karol

Identyfikatory

DOI

10.2478/bioal-2022-0079

• Konferencja: 4th Jagiellonian Symposium on Advances in Particle Physics and Medicine, Krakow, 10-15 July 2022
• Języki publikacji: EN

Abstrakty

EN

Quantitative imaging (i.e., providing not just an image but also the related data) guidance in proton radiation therapy to achieve and monitor the precision of planned radiation energy deposition field in-vivo (a.k.a. proton range verification) is one of the most underinvested aspects of radiation cancer treatment despite that it may dramatically enhance the treatment accuracy and lower the exposure related toxicity improving the entire outcome of cancer therapy. In this article, we briefly describe the effort of the TPPT Consortium (a collaborative effort of groups from the University of Texas and Portugal) on building a time-of-flight positronemission-tomography (PET) scanner to be used in preclinical studies for proton therapy at MD Anderson Proton Center in Houston. We also discuss some related ideas towards improving and expanding the use of PET detectors, including the total body imaging.

Słowa kluczowe

EN

proton therapy; imaging-guidance proton therapy; proton range verification; PET scanner; total-body PET; time-of-flight PET scanner; TOF PET; nuclear medical imaging; radiopharmaceuticals; hypoxia; cancer; theranostics; FLASH treatment; multi-modal treatment; TPPT Consortium

• Wydawca: Uniwersytet Jagielloński - Collegium Medicum ; Index Copernicus Sp. z o.o.
• Czasopismo: Bio-Algorithms and Med-Systems
• Rocznik: 2022
• Tom: Vol. 18, no. 1
• Strony: 96--106
• Opis fizyczny: Bibliogr. 67 poz., rys.

Twórcy

autor

Lang Karol

• Department of Physics, University of Texas at Austin, Austin TX 78712, USA

Bibliografia

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Uwagi

Opublikowane przez Sciendo. Opracowanie rekordu ze środków MEiN, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2022-2023).