Identification of chemical constituents in SiWu decoction by UHPLC-DAD-TOF/MS

• Autorzy: Zhu M. , Duan J. , Tang Y. P. , Guo J. M. , Shang E. X. , Zhu Z. H.
• Języki publikacji: EN

Abstrakty

EN

An efficient and robust method for analyzing constituents of a well-known traditional Chinese medicine (TCM) formula SiWu decoction (SWD) contains AngelicaeSinensis Radix (ASR), Chuanxiong Rhizoma (CR), Paeoniae Radix Alba (PRA), and RehmanniaeRadix Praeparata (RRP) by ultra high-performance liquid chromatography (UHPLC)/time-of-flight mass spectrometry (TOF-MS) was established. The method efficiently applied to the separation of 75 compounds, including organic acids, phthalides, phenylpropanoid glycosides, iridoid glycosides, monoterpene glycosides, and galloyl glycosides in the complex prescription, 52 compounds in this study can be unambiguously identified or tentatively characterized. The separation was achieved within 20 min at the optimized chromatographic conditions. Our study provided a reliable and high-efficient method for the understanding of the chemical basis of SWD.

Słowa kluczowe

EN

SiWu decoction; Angelicae Sinensis Radix; Chuanxiong Rhizoma; Paeoniae Radix Alba; Rehmanniae Radix Praeparata

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2014
• Tom: Vol. 26, no. 3
• Strony: 517--537
• Opis fizyczny: Bibliogr. 27 poz., rys., tab.

Twórcy

autor

Zhu M.

• The First Affiliated Hospital of Nanjing University of Chinese Medicine West Phoenix Street, 150-1 210036 Nanjing China

autor

Duan J.

• Nanjing University of Chinese Medicine Jiangsu Key Laboratory for High Technology Research of TCM Formulae Xianlin Road 138 210023 Nanjing China

autor

Tang Y. P.

• Nanjing University of Chinese Medicine Jiangsu Key Laboratory for High Technology Research of TCM Formulae Xianlin Road 138 210023 Nanjing China

autor

Guo J. M.

• Nanjing University of Chinese Medicine Jiangsu Key Laboratory for High Technology Research of TCM Formulae Xianlin Road 138 210023 Nanjing China

autor

Shang E. X.

• Nanjing University of Chinese Medicine Jiangsu Key Laboratory for High Technology Research of TCM Formulae Xianlin Road 138 210023 Nanjing China

autor

Zhu Z. H.

• Nanjing University of Chinese Medicine Jiangsu Key Laboratory for High Technology Research of TCM Formulae Xianlin Road 138 210023 Nanjing China

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