Investigating optimal conditions for obtaining medicinal extracts with the best functional properties from Kleinia anteuphorbium L.

• Autorzy: Naama Amal , Aghoutane Basma , EL-Otmani Najlae , EL Monfalouti Hanae , Kartah Badr Eddine

Identyfikatory

DOI

10.12912/27197050/199624

• Języki publikacji: EN

Abstrakty

EN

Kleinia anteuphorbium L. is a medicinal plant widely utilized in traditional medicine by the Souss-Massa population. This study aimed to investigate the best extraction conditions, including method and solvents, to achieve the highest polyphenol, flavonoid, antioxidant, and antibacterial activities. The polyphenol and flavonoid contents were quantified using spectrophotometric methods, while the antioxidant activity was assessed through Ferric Reducing Power (FRAP) and 2,2-diphenyl-picrylhydrazyl radical (DPPH) scavenging assays. The antibacterial activity was assessed against four pathogenic clinical isolates: P. aeruginosa, E. coli, K. pneumonia, and S. aureus. The phytochemical analysis revealed that all extracts of Kleinia anteuphorbium exhibited high polyphenol and flavonoid contents, along with significant antioxidant activity. Moreover, the extracts showed inhibitory effects against the tested bacteria strains. The GC-MS analysis revealed the existence of abundant bioactive compounds, with potential therapeutic activities. These findings suggest that Kleinia anteuphorbium has promising potential as a medicinal plant.

Słowa kluczowe

EN

antibacterial; polyphenols; flavonoids; phenolics; antioxidants; GC-MS

• Wydawca: Lubelski Oddział Polskiego Towarzystwo Inżynierii Ekologicznej ; Lublin University of Technology ; WNGB Wydawnictwo Naukowe
• Czasopismo: Ecological Engineering & Environmental Technology
• Rocznik: 2025
• Tom: Vol. 26, iss. 3
• Strony: 171--182
• Opis fizyczny: Bibliogr. 45 poz., rys., tab.

Twórcy

autor

Naama Amal

• Laboratory of Plant Chemistry, Organic And Bio-Organic Synthesis, Faculty of Sciences, University Mohammed V, Rabat, Morocco
• [e-mail]

• https://orcid.org/0009-0003-9508-922X

autor

Aghoutane Basma

• Laboratory of Plant Chemistry, Organic And Bio-Organic Synthesis, Faculty of Sciences, University Mohammed V, Rabat, Morocco

• https://orcid.org/0009-0007-0977-0262

autor

EL-Otmani Najlae

• Therapeutic Chemistry Laboratory, Department of Drug Sciences, Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco

• https://orcid.org/0000-0002-3018-4563

autor

EL Monfalouti Hanae

• Laboratory of Plant Chemistry, Organic And Bio-Organic Synthesis, Faculty of Sciences, University Mohammed V, Rabat, Morocco

• https://orcid.org/0000-0002-5192-9034

autor

Kartah Badr Eddine

• Laboratory of Plant Chemistry, Organic And Bio-Organic Synthesis, Faculty of Sciences, University Mohammed V, Rabat, Morocco

• https://orcid.org/0000-0001-5114-0618

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