Solubility of a pharmacological intermediate drug Isatin in different solvents at various temperatures

• Autorzy: Baluja S. , Bhalodia R. , Bhatt M. , Vekariya N. , Gajera R.
• Języki publikacji: EN

Abstrakty

EN

The solubility of isatin in different solvents was studied by a gravimetrical method from (298.15 to 318.15) K under atmospheric pressure and the solubility data were correlated against temperature. The solvents selected for the present study are: water, methanol, ethanol, 1-butanol, dichloromethane, dichloroethane, chloroform and carbon tetra chloride. Among chlorinated solvents, solubility is observed to be maximum in 1, 2-dichloroethane and minimum in dichloromethane whereas in alcohols, maximum solubility is observed in methanol. In water, solubility is found to be minimum. Further, some thermodynamic parameters such as Gibb’s energy (ΔGsol), heat of solution (ΔHsol) and entropy of solution (ΔSsol) have also been evaluated.

Słowa kluczowe

EN

Isatin; solubility; Thermodynamic parameters

• Wydawca: Przedsiębiorstwo Wydawnictw Naukowych "DARWIN"
• Czasopismo: International Letters of Chemistry, Physics and Astronomy
• Rocznik: 2013
• Tom: Vol. 12
• Strony: 36--46
• Opis fizyczny: Bibliogr. 26 poz., tab., rys.

Twórcy

autor

Baluja S.

• Physical Chemical Laboratory, Department of Chemistry, Saurashtra University, Rajkot 360 005, India

autor

Bhalodia R.

• Physical Chemical Laboratory, Department of Chemistry, Saurashtra University, Rajkot 360 005, India

autor

Bhatt M.

• Physical Chemical Laboratory, Department of Chemistry, Saurashtra University, Rajkot 360 005, India

autor

Vekariya N.

• Physical Chemical Laboratory, Department of Chemistry, Saurashtra University, Rajkot 360 005, India

autor

Gajera R.

• Physical Chemical Laboratory, Department of Chemistry, Saurashtra University, Rajkot 360 005, India

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