Comparison of sulphonamides decomposition efficiency in ozonation and enzymatic oxidation processes

• Autorzy: Lemańska Natalia , Felis Ewa , Poraj-Kobielska Marzena , Gajda-Meissner Zuzanna , Hofrichter Martin

Identyfikatory

DOI

10.24425/aep.2021.136443

Warianty tytułu

PL

Porównanie efektywności rozkładu sulfonamidów w procesach ozonowania i utleniania enzymatycznego

• Języki publikacji: EN

Abstrakty

EN

Sulphonamides (SAs) are one of the most frequently detected anthropogenic micropollutants in the aquatic environment and their presence in it may pose a threat to living organisms. The aim of the study was to determine susceptibility of selected sulphonamides, i.e. sulfadiazine (SDZ) and sulfamethazine (SMZ), to degradation in the ozonation process and in enzymatic oxidation by unspecific peroxygenase extracted from Agrocybe aegerita mushroom (AaeUPO). Moreover, the acute toxicity of the aqueous solution of the selected sulphonamides (SMZ and SDZ) before and after mentioned treatment processes were studied on the freshwater crustacean Daphnia magna. Initial concentrations were equal to 2×10^-5 M for sulfadiazine and 1.8×10^-5 M for sulfamethazine. The percentage of transformation for the O3 process was at the level 95% for both SDZ and SMZ (after 10 s of the process), whilst enzymatic oxidation of SDZ and SMZ by AaeUPO caused transformation efficiencies at the levels of 97% and 94% (after 1 minute of the process), respectively. The second order rate constants of selected sulfonamides with molecular ozone and fungal peroxidase were also determined in the research. EC₅₀ (median effective concentration) values from toxicity test on D. magna were found in the range from 14.6% to 37.2%, depending on the type of the process. The conducted oxidation processes were efficient in degradation of selected sulphonamides. The toxicity of the mixtures before and after treatment was comparable and did not change significantly. The research have shown that biological processes are not always safer for living organisms compared to the chemical processes.

PL

Sulfonamidy są jednymi z najczęściej wykrywanych mikrozanieczyszczeń antropogenicznych w środowisku wodnym, a ich obecność w nim może stanowić zagrożenie dla organizmów żywych. Celem badań było określenie podatności wybranych sulfonamidów, tj. sulfadiazyny i sulfametazyny na degradację w procesie ozonowania i utleniania enzymatycznego przez nieswoistą peroksygenazę ekstrahowaną z grzyba Agrocybe aegerita (AaeUPO). Ponadto badano toksyczność ostrą wodnego roztworu wybranych sulfonamidów przed i po wspomnianych procesach na słodkowodnym skorupiaku Daphnia magna. Początkowe stężenia wynosiły odpowiednio: 2×10^-5 M (sulfadiazyna) i 1,8×10^-5 M (sulfametazyna). Procent transformacji dla procesu O3 kształtował się na poziomie 95%, zarówno dla sulfadiazyny, jak i sulfametazyny, natomiast enzymatyczne utlenianie przez AaeUPO spowodowało odpowiednio transformacje badanych leków na poziomie 97% (sulfadiazyna) i 94% (sulfametazyna). W badaniach wyznaczono drugorzędowe stałe szybkości reakcji badanych sulfonamidów z ozonem cząsteczkowym i peroksydazą grzybową. Wartości EC₅₀ z badań ekotoksyczności na D. magna wahały się od 14,6% do 37,2%, w zależności od rodzaju procesu. Wybrane do badań procesy utleniania okazały się być skuteczne w degradacji (transformacji) badanych sulfonamidów. Toksyczność mieszanin przed i po procesach była porównywalna, i nie zmieniała się znacząco, jednak to mieszaniny przed i po procesach enzymatycznej oksydacji charakteryzowały się wyższą toksycznością w porównaniu do mieszanin przed i po procesie ozonowania. Badania wykazały, że procesy biologiczne nie zawsze są bezpieczniejsze dla organizmów żywych w porównaniu z procesami chemicznymi.

Słowa kluczowe

EN

sulphonamides; ozonation; unspecific aromatic peroxygenase; second order rate constants; D. magna; toxicity

PL

sulfonamidy; ozonowanie; niespecyficzna aromatyczna peroksygenaza; stałe wskaźnika drugiego rzędu; D. magna; toksyczność

• Wydawca: Institute of Environmental Engineering, Polish Academy of Sciences
• Czasopismo: Archives of Environmental Protection
• Rocznik: 2021
• Tom: Vol. 47, no. 1
• Strony: 10--18
• Opis fizyczny: Bibliogr. 42 poz., tab., wykr.

Twórcy

autor

Lemańska Natalia

• EkoNorm Sp. z o.o., Katowice, Poland

autor

Felis Ewa

• The Silesian University of Technology, Gliwice, Poland

autor

Poraj-Kobielska Marzena

• Technische Universität Dresden, Germany

autor

Gajda-Meissner Zuzanna

• School of Life Sciences, Heriot-Watt University, Edinburgh, United Kingdom

autor

Hofrichter Martin

• Technische Universität Dresden, Germany

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2021).