Characterization of natural products from the peel of Lagenaria siceraria fruit using chromatographic techniques

• Autorzy: Liaqat I. , Ahmed D. , Saleem A. , Masih R. , Chaudhery R.

Identyfikatory

DOI

10.1556/1326.2017.00247

• Języki publikacji: EN

Abstrakty

EN

Herbal products, which comprise a wide variety of bioactive molecules, have been used as remedies for different diseases throughout history. Lagenaria siceraria, a fruit vegetable, is employed in folk medicine as a treatment for various disorders including diabetes, hyperlipidemia, and heart and liver ailments. In the present work, a number of compounds were isolated and characterized from the ethyl acetate fraction of the methanolic extract of its peel, including β-sitosterol, vanillin, quercetin, rutin, 3-tert-butyl-4-hydroxyanisole, stearic acid, 2,4-bis(1,1-dimethylethyl)phenol, 2,2′-methylenebis[6-(1,1-dimethylethyl)-4-methylphenol], 1,2-benzenedicarboxylic acid mono(2-ethylhexyl) ester, hexadecanoic acid and its methyl ester, (Z,Z)-9,12-ocatdecadienoic acid and its ester, and (Z,Z,Z)-9,12,15-ocatdecatrienoic acid methyl ester. Separation of the phytochemicals was done using column and thin-layer chromatography, while gas chromatography–mass spectrometry (GC–MS), liquid chromatography-mass spectrometry (LC–MS), and high-performance liquid chromatography (HPLC) were employed for their identification. These compounds are being reported for the first time from the peel of the fruit of L. siceraria. The results provide a possible chemical rationale for the medicinal applications of this fruit.

Słowa kluczowe

EN

Lagenaria siceraria; peel; bioactive compounds

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2018
• Tom: Vol. 30, no. 3
• Strony: 191--194
• Opis fizyczny: Bibliogr. 18 poz., rys.

Twórcy

autor

Liaqat I.

• Forman Christian College (a Chartered University), Ferozpur Road, Lahore, Pakistan

autor

Ahmed D.

• Forman Christian College (a Chartered University), Ferozpur Road, Lahore, Pakistan

autor

Saleem A.

• University of Manchester, Manchester, UK

autor

Masih R.

• Forman Christian College (a Chartered University), Ferozpur Road, Lahore, Pakistan

autor

Chaudhery R.

• Forman Christian College (a Chartered University), Ferozpur Road, Lahore, Pakistan

Bibliografia

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Uwagi

PL

Opracowanie rekordu w ramach umowy 509/P-DUN/2018 ze środków MNiSW przeznaczonych na działalność upowszechniającą naukę (2018).