Praktyczne aspekty zastosowania chityny i jej pochodnych w leczeniu ran

Skołucka-Szary, K.; Rieske, P.; Piaskowski, S.

Artykuł - szczegóły

Tytuł artykułu

Praktyczne aspekty zastosowania chityny i jej pochodnych w leczeniu ran

Autorzy

Skołucka-Szary K. , Rieske P. , Piaskowski S.

Treść / Zawartość

Pełne teksty:

Pobierz

Pobierz

Identyfikatory

Warianty tytułu

Practical aspects related to application of chitin and its derivatives in wound management

Języki publikacji

PL EN

Abstrakty

Chityna jest polisacharydem o unikatowych właściwościach. W pracy zostały omówione właściwości biologiczne chityny, ograniczenia jej stosowania w przemyśle oraz kierunki modyfikacji chemicznej. Ze względu na rosnące zapotrzebowanie na nowoczesne materiały opatrunkowe, przedstawiono możliwości wykorzystania chityny i jej dwóch najbardziej popularnych pochodnych: chitozanu i dibutyrylochityny, w praktyce klinicznej oraz scharakteryzowano komercyjnie dostępne opatrunki na bazie chityny i chitozanu.

Chitin is a polysaccharide with unique properties. In this paper, we reviewed biological properties of chitin, limitations of its industrial applications and directions of its further chemical modifications. In view of growing demand for the modern wound dressing materials, we discussed potential clinical applications of chitin and its two most popular derivatives: chitosan and dibutyryl chitin. In addition, we characterized commercially available chitin- and chitosan- based wound dressings.

Słowa kluczowe

chityna chitozan dibutyrylochityna leczenie ran

chitin chitosan dibutyryl chitin wound healing

Wydawca

Stowarzyszenie Inżynierów i Techników Przemysłu Chemicznego, ZW CHEMPRESS-SITPChem

Czasopismo

Chemik

Rocznik

2016

Tom

Vol. 70, nr 2

Strony

89--98

Opis fizyczny

Bibliogr. 66 poz., rys., tab.

Twórcy

autor

Skołucka-Szary K.

karolina.skolucka@celther.com

Laboratorium Naukowo-Badawcze, Celther Polska Sp. z o.o., Zakroczym

autor

Rieske P.

Laboratorium Naukowo-Badawcze, Celther Polska Sp. z o.o., Zakroczym

autor

Piaskowski S.

Laboratorium Naukowo-Badawcze, Celther Polska Sp. z o.o., Zakroczym

Bibliografia

1. Khoushab F., Yamabhai M.: Chitin Research Revised. Marine Drugs 2010, 8, 7, 1988–2012.
2. Thakur V.K., Thakur M.K.: Eco- friendly Polymer Nanocomposites. Chemistry and Applications. Springer 2015, 51.
3. Struszczyk M.H.: Chitin and Chitosan Part I: Properties and Production. Polimery 2002, 47, 5, 316–325.
4. Percot A., Viton C., Domard A.: Optimization of chitin extraction from shrimp shells. Biomacromolecules 2003, 4, 1, 12–8.
5. Lenardon M.D., Munro C.A., Gow N.A.: Chitin synthesis and fungal pathogenesis. Current Opinion in Microbiology 2010, 13, 4, 416–423.
6. Ehrlich H.: Chitin and Collagen as Universal and Alternative Templates in Biomineralization. International Geology Review 2010, 52, 7–8, 661–699.
7. Merzendorfer H., Zimoch L.: Chitin metabolism in insects: structure, function and regulation of chitin synthases and chitinases. The Journal of Experimental Biology 2003, 206, 24, 4393–4412.
8. Kaya M., Seyyar O., Baran T., Erdoğan S., Kar M.: A Physicochemical Characterization of the Fully Acetylated Chitin Structure Isolated from Two Spider Species. International Journal of Biological Macromolecules 2014, 65, 553–558.
9. Juárez-de la Rosa B.A., Quintana P., Ardisson P.L., Yáñez-Limón J.M., Alvarado-Gil J.J.: Effects of thermal treatments on the structure of two black coral species chitinous exoskeleton. Journal of Material Science 2012, 47, 2, 990–998.
10. Hayes M., Carney B., Slater J., Brück W.: Mining marine shellfish wastes for bioactive molecules: chitin and chitosan. Part A: extraction methods. Biotechnology Journal 2008, 3, 7, 871–877.
11. Younes I., Rinaudo M.: Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications. Marine Drugs 2015, 13, 1133–1174.
12. Arbia W., Arbia L., Adour L., Amrane A.: Chitin Extraction from Crustacean Shells Using Biological Methods – A Review. Food Technology and Biotechnology 2013, 51, 1, 12–25.
13. http://www.ncbi.nlm.nih.gov/pubmed/?term=chitin, 30.01.2016.
14. http://www.ncbi.nlm.nih.gov/pubmed/17743391, 30.01.2016.
15. Rinaudo M.: Chitin and chitosan: Properties and applications. Progress in Polymer Science 2006, 31, 7, 603–632.
16. Yu L.: Biodegradable Polymer Blends and Composites from Renewable Resources. John Wiley & Sons 2009, 136.
17. Jayakumar R., Prabaharan M., Sudheesh Kumar P.T., Nair S.V., Tamura H.: Biomaterials based on chitin and chitosan in wound dressing applications. Biotechnology Advances 2011, 29, 3, 322–337.
18. Anitha A., Sowmya S., Sudheesh Kumar P.T., Deepthi S., Chennazhi K.P., Ehrlich H.: Chitin and chitosan in selected biomedical applications. Progress in Polymer Science 2014, 39, 9, 1644–1667.
19. Wan A.C.A., Tai B.C.U.: CHITIN – A promising biomaterial for tissue engineering and stem cell technologies. Biotechnology Advances 2013, 1, 1776–1785.
20. Azuma K., Izumi R., Osaki T., Ifuku S., Morimoto M., Saimoto H., Minami S., Okamoto Y.: Chitin, Chitosan, and Its Derivatives for Wound Healing: Old and New Materials. Journal of Functional Biomaterials 2015, 6, 1, 104–142.
21. Skórkowska-Telichowska K., Bugajska-Prusak A., Pluciński P., Rybak Z., Szopa J.: Fizjologia i patologia przewlekle niegojących się owrzodzeń oraz sposoby ich miejscowego leczenia w świetle współczesnej wiedzy medycznej. Dermatologia Praktyczna 2009, 5, 15–29.
22. Muzzarelli R.A.A.: Human enzymatic activities related to the therapeutic administration of chitin derivatives. CMLS Cellular and Molecular Life Sciences 1997, 53, 131–140.
23. Muzzarelli R.A.A.: Chitins and chitosan for the repair of wound skin, nerve, cartilage and bone. Carbohydrate Polymers 2009, 76, 2, 167–182.
24. Menke N.B., Ward K.R., Witten T.M., Bonchev D.G., Diegelmann R.F.: Impaired wound healing. Clinics in Dermatology 2007, 25, 1, 19–25.
25. Gottrup F.: A specialized wound- healing center concept: importance of multidisciplinary department structure and surgical treatment facilities in the treatment of chronic wounds. The American Journal of Surgery 2004, 187, 38S–43S.
26. Rudall K.M., Kenchington W.: The chitin system. Biological Reviews 1973, 48, 4, 597–633.
27. Rudall K.M.: Chitin and its association with other molecules. Journal of Polymer Science Part C: Polymer Symposia 1969, 28, 1, 83–102.
28. Lavall R.L., Assis O.B., Campana-Filho S.P.: Beta-chitin from the pens of Loligo sp.: extraction and characterization. Bioresource Technology 2007, 98, 13, 2465–2472.
29. Draczyński Z.: Kopoliester Butyrylo-Acetylowy Chityny jako nowy aktywny składnik nanokompozytów polimerowo-włóknistych. Zeszyty naukowe, Politechnika Łódzka 2013, Nr 1159.
30. Hu X., Du Y., Tang Y., Wang Q., Feng T., Yang J. et al.: Solubility and property of chitin in NaOH/urea aqueous solution. Carbohydrate Polymers 2007, 70, 4, 451–458.
31. Chen B., Sun K., Zhang K.: Rheological properties of chitin/lithium chloride, N,N-dimethyl acetamide solutions. Carbohydrate Polymers 2004, 58, 1, 65–69.
32. Terbojevich M., Carraro C., Cosani A.: Solution studies of the chitin-lithium chloride-N,N-dimethylacetamide system. Carbohydrate Research 1988, 180, 1, 73–86.
33. Rutherford F.A., Austin P.R., Muzzarelli R.A.A., Pariser E.R., edit.: Proceedings of the First International Conference on Chitin/Chitosan. MIT Sea Grant Report MITSG 1978, 78–8, 182–191.
34. Pillai C.K.S., Paul W., Sharma C.P.: Chitin and chitosan polymers: Chemistry, solubility and fiber formation. Progress in Polymer Science 2009, 34, 7, 641–678.
35. Kaifu K., Nishi N., Komai T., Tokura S., Somorin O.: Studies on chitin. V. formylation, propionylation and butyrylation of chitin. Polymer Journal 1981, 13, 241–245.
36. Kurita K.: Controlled functionalization of the polysaccharide chitin. Progress in Polymer Science 2001, 26, 9, 1921–1971.
37. Skołucka-Szary K., Ramięga A., Piaskowska W., Janicki B., Grala M., Rieske P., Stoczyńska–Fidelus E., Piaskowski S.: Chitin dipentanoate as the new technologically usable biomaterial. Materials Science and Engineering: C Materials for Biological Applications 2015, 55, 50–60.
38. Skołucka-Szary K., Ramięga A., Piaskowska W., Janicki B., Grala M., Rieske P., Bartczak Z., Piaskowski S.: Synthesis and physicochemical characterization of chitin dihexanoate - A new biocompatible chitin derivative - In comparison to chitin dibutyrate. Materials Science and Engineering: C Materials for Biological Applications 2016, 60, 489–502.
39. http://www.ncbi.nlm.nih.gov/pubmed/?term=chitosan, 30.01.2016.
40. Mourya V.K., Inamdar N.: Chitosan-modifications and applications: Opportunities galore. Reactive and Functional Polymers 2008, 68, 1013-1051.
41. Struszczyk H., Kivekäs O.: Microcrystalline Chitosan – Some Areas of Application. British Polymer Journal 1990, 23, 261.
42. Yang B.Y., Ding Q., Montgomery R.: Preparation and physical properties of chitin fatty esters. Carbohydrate Research 2009, 344, 3, 336–342.
43. Szosland L.: Synthesis of highly substituted butyryl chitin in the presence of perchloric acid. Journal of Bioactive and Compatible Polymers, Journal of Bioactive and Compatible Polymers 1996, 11, 1, 61–71.
44. Błasińska A., Krucińska I., Chrzanowski M.: Dibutyrylchitin nonwoven biomaterials manufactured using electrospinning method. FIBRES & TEXTILES in Eastern Europe 2004, 4, 48, 51–55.
45. Szosland L., Stęplewski W.: Rheological characteristic of dibutyrylchitin semiconcentrated solutions and wet spinning of dibutyrylchitin fiber. Advances in Chitin Science 1998, II, 531–536.
46. Dai T., Tanaka M., Huang Y.Y., Hamblin M.R.: Chitosan preparations for wounds and burns: antimicrobial and wound healing effects. Expert Review of Anti-infective Therapy 2011, 9, 7, 857–879.
47. Yang T.L.: Chitin - based Materials in Tissue Engineering: Applications in Soft Tissue and Epithelial Organ. International Journal of Molecular Sciences 2011, 12, 3, 1936–1963.
48. Cheung R.C.F., Ng T.B., Wong J.H., Chan W.Y.: Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications. Marine Drugs 2015, 13, 8, 5156–5186.
49. Guo R., Xu S., Ma L., Huang A., Gao C.: Enhanced angiogenesis of geneactivated dermal equivalent for treatment of full thickness incisional wounds in a porcine model. Biomaterials 2010, 31, 7308–7320.
50. Liu X., Ma L., Liang J., Zhang B., Teng J., Gao C.: RNAi functionalized collagen-chitosan/silicone membranę bilayer dermal equivalent for full thickness skin regeneration with inhibited scarring. Biomaterials 2013, 34, 2038–2048.
51. Lu S., Gao W., Gu H.Y.: Construction, application and biosafety of silver nanocrystalline chitosan wound dressing. Burns 2008, 34, 623–628.
52. Kucharska M., Struszczyk M.H., Niekraszewicz A., Ciechańska D., Witczak E., Tarkowska S., Fortuniak K., Gulbas-Diaz A., Rogaczewska A., Płoszaj I., Pluta A., Gąsiorowski T.: Tromboguard® – first aid wound dressing. Progress on Chemistry and Application of Chitin and Its Derivatives 2011, XVI, 121–130.
53. http://woundcare-today.com/products-pyramid/protease-modulators/kytocelr-gelling-fibre-dressing, 30.01.2016.
54. http://www.aspenmedicaleurope.com/wp-content/uploads/2013/10/ Denyer- J.-Gibson-E.-KytoCel...-in-Severe-EB-Wounds-UK-2014–550L10.14.pdf, 30.01.2016.
55. Chilarski A., Szosland L., Krucińska I., Kiekens P., Błasińska A., Schoukens G., Cisło R., Szumielewicz J.: Novel Dressing Materials Accelerating Wound Healing from Dibutyrylchitin. FIBRES & TEXTILES in Eastern Europe 2007, 15, 4, 63, 77–81.
56. Muzzarelli A.A.R., Guerrieri M., Goteri G., Muzzarelli C., Armeni T., Ghiselli R., Cornelissen M.: The biocompatibility of dibutyryl chitin in the context of wound dressings. Biomaterials 2005, 26, 5844–5854.
57. Blasinska A., Drobnik J.: Effects of Nonwovens Mats of Di-O-butyrylchitin and Related Polymers on the Process of Wound Healing. Biomacromolecules 2008, 9, 776–782.
58. Krucińska I., Komisarczyk A., Paluch D., Szymonowicz M., Zywicka B., Pielka S.: The impact of the dibutyrylchitin molar mass on the bioactive dressings used to treat soft tissue wounds. Journal of Biomedical Materials Research. Part B. Applied Biomaterials 2012, 100, 1, 11–22.
59. Kiekens P., Szosland L., Krucińska I., Schoukens G., Błasińska A., Chilarski A., Kornobis E.: Novel dibutyrylchitin dressing materials stimulating wound healing. AUTEX 2006 - NC State University - Conference Proceedings 2006.
60. Mazurek P., Kuliński S., Gosk J.: Możliwości wykorzystania chityny i chitozanu w leczeniu ran. Polimery w Medycynie 2013, 43, 4, 297–302.
61. Inamdar N., Mourya V.: Chitosan and Low Molecular Weight Chitosan: Biological and Biomedical Applications. Advanced Biomaterials and Biodevices (ed. Tiwari A., Nordin A.N.). John Wiley & Sons 2014, 182–242.
62. Niekraszewicz A.: Chitosan Medical Dressings. FIBRES & TEXTILES in Eastern Europe 2005, 13, 6(54), 16–18.
63. http://lunainc.com/wp-content/uploads/2014/04/Hemostatic-Agents-August-2013.pdf, 30.01.2016.
64. http://isap.sejm.gov.pl/DetailsServlet?id=WDU20101070679, 30.01.2016.
65. http://dziennikustaw.gov.pl/DU/2015/1918, 30.01.2016.
66. Struszczyk M.H., Struszczyk J.K.: Medical applications of chitin and its derivatives. Polish Chitin Society Monograph 2007, XII, 139–147.

Uwagi

Opracowanie ze środków MNiSW w ramach umowy 812/P-DUN/2016 na działalność upowszechniającą naukę.

Typ dokumentu

Bibliografia

Identyfikator YADDA

bwmeta1.element.baztech-5a711cd4-ddb6-49b8-a388-46f2d1f37101