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Transistor Effect in the Cochlear Amplifier

Treść / Zawartość
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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The paper presents a new electromechanical amplifying device i.e., an electromechanical biological transistor. This device is located in the outer hair cell (OHC), and constitutes a part of the Cochlear amplifier. The physical principle of operation of this new amplifying device is based on the phenomenon of forward mechanoelectrical transduction that occurs in the OHC’s stereocilia. Operation of this device is similar to that of classical electronic Field Effect Transistor (FET). In the considered electromechanical transistor the input signal is a mechanical (acoustic) signal. Whereas the output signal is an electric signal. It has been shown that the proposed electromechanical transistor can play a role of the active electromechanical controlled element that has the ability to amplify the power of input AC signals. The power required to amplify the input signals is extracted from a battery of DC voltage. In the considered electromechanical transistor, that operates in the amplifier circuit, mechanical input signal controls the flow of electric energy in the output circuit, from a battery of DC voltage to the load resistance. Small signal equivalent electrical circuit of the electromechanical transistor is developed. Numerical values of the electrical parameters of the equivalent circuit were evaluated. The range, which covers the levels of input signals (force and velocity) and output signals (voltage, current) was determined. The obtained data are consistent with physiological data. Exemplary numerical values of currents, voltages, forces, vibrational velocities and power gain (for the assumed input power levels below 1 picowatt (〖10〗^(-12) W), were given. This new electromechanical active device (transistor) can be responsible for power amplification in the cochlear amplifier in the inner ear.
Rocznik
Strony
117--124
Opis fizyczny
Bibliogr. 26 poz., rys., tab.
Twórcy
  • Institute of Fundamental Technological Research Polish Academy of Sciences Pawińskiego 5B, 02-106 Warszawa, Poland
autor
  • Institute of Fundamental Technological Research Polish Academy of Sciences Pawińskiego 5B, 02-106 Warszawa, Poland
Bibliografia
  • 1. Ashmore J., Avan P., Brownell W.E., Dallos p., Dierkes K., Fettiplace R., Grosh K., Hackney C.M., Hudspeth A.J., Julicher F., Lindner B., Meaud J. Petit C., Santos Sacchi J.R., Canlon C., “The remarkable cochlear amplifier”, Hearing Research, Vol. 266, pp. 1-17, 2010.
  • 2. Chan V., Liu S.C., van Schalk A., “AER EAR:’ A matched silicon cochlea pair event representation interface”, IEEE Trans on Circuits and Systems I, vol. 54, no. 1, pp. 48-59, Jan 2007.
  • 3. Cohen A., Furst M., “Integration of outer hair cell activity in one-dimensional cochlear model”, Journal of the Acoustical Society of America, vol. 115, no 5, pp.2185-2192, May 2004.
  • 4. Davis H., “An active process in cochlear mechanics”, Hearing Research, Vol. 9, No 1, pp. 79-90, January 1983.
  • 5. Eisenberg B., “Ions in fluctuating channels: Transistors alive”, Fluctuation and Noise Letters, vol. 11, no. 2, 00076 (20 pages), 2012.
  • 6. EGUILUZ V.M., OSPECK M., CHOE Y., HUDSPETH A.J., MAGNASCO M.O., (2000), “Essential nonlinearities in hearing”, Physical Review Letters, 84, 5232-5235.
  • 7. Fettiplace R., “Active hair cell movement in auditory hair cells”, Journal of Physiology, 576, pp. 29-36, October 2006.
  • 8. Galbraith C.J., “Cochlea-based RF channelizing filters”, IEEE Trans on Circuits and Systems I, vol. 55, no. 4, pp. 969-979, May 2008.
  • 9. GOLD T. (1948), Hearing. II. The physical basis of the action of the cochlea, Proc. R. Soc. London B. Biol. Sci. 135, 492-498.
  • 10. Golde W., Electronic Systems [in Polish], Vol. II, Chap.5, WNT, Warsaw, 1976.
  • 11. Keener J., Sneyd J., “Mathematical Physiology. II: Systems Physiology”, Springer, Ch. 20, 2009.
  • 12. Kiełczyński P., “Power amplification and selectivity in the cochlear amplifier”, Archives of Acoustics, vol. 38, no. 1, pp. 83-92, 2013.
  • 13. Letaw H., Bardeen J., “Electrolytic analog transistor”, Journal of Applied Physics, vol. 25, no. 5, pp. 600-606, 1954.
  • 14. Liao Z., Popel A., Brownell W.E., Spector A.A., “Effect of voltage-dependent membrane properties on active force generation in cochlear outer hair cell”, Journal of the Acoustical Society of America, vol. 118, no 6, pp. 3737-3746, December 2005.
  • 15. Mandal S., Shakespear R., “A bio-inspired cochlear heterodyning architecture for an RF cochlea”, IEEE Trans on Circuits and Systems I, vol. 58, no. 7, pp. 1647-1660, July 2011.
  • 16. Mead C., Analog VLSI and neural systems, Addison-Wesley, , Boston, New York, 1989.
  • 17. Mistrik P., Mullaney C., Mammano F., Ashmore J., “Three-dimensional current flow in a large-scale model of the cochlea and the mechanism of amplification of sound”, Journal of Royal Society Interface, vol. 6, no. 32, pp. 279-291, 2009.
  • 18. Nin F., Reinchenbach T., Fisher J.A.N., and Hudspeth A.J., “Contribution of active hair-bundle motility to nonlinear amplification in the mammalian cochlea”, PNAS, vol. 109, no. 51, pp. 21076-21080, Dec. 18, 2012.
  • 19. Pierce J.R., and David E.E., Man’s world of sound, Doubleday&Company, New York, 1958.
  • 20. Ramamoorthy S., Deo N.V., “A mechano-electro-acoustical model for the cochlea: Response to acoustic stimuli’, Journal of the Acoustical Society of America, vol. 121, no 5, pp.2758-2773, May 2007.
  • 21. Ramamoorthy S., Nuttal A.L., “Outer hair cell somatic electromotility in vivo and power transfer to the organ of Corti”, Biophysical Journal, vol. 102, no. 2, pp. 388-398, 2012.
  • 22. Rattay R., Gebeshuber I.C., Gitter A.H., “The mammalian auditory hair cell: A simple electric circuit model”, Journal of the Acoustical Society of America, vol. 103, no 3, pp. 1558-1565, March 1998.
  • 23. Shakespear R., Ultra low power bioelectronics, Cambridge University Press, New York, 2010.
  • 24. Shockley W., Electron and holes in semiconductors with applications to transistor electronics, R.E. Krieger Pub. Co, New York, 1956.
  • 25. Shockley W., “Transistors”, in The age of Electronics, ed. By C.F.J. Overhage, McGraw-Hill, New York, 1962.
  • 26. Weitzel E.K., Tasker R., Brownell W.E., “Outer hair cell piezoelectricity: Frequency response enhancement and resonance behavior”, Journal of the Acoustical Society of America, vol. 114, no 3, pp. 1462-1466, September 2003.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-5a4e5145-a4f4-4fbb-9a70-06e3b8f63ca0
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