Synthesis, Pharmacological and Insect Antifeedant Activities of some 3-(2-naphthyl)-5-(substituted phenyl)-4,5-dihydroisoxazoles

• Autorzy: Thirunarayanan G. , Sathiyendiran V.

Identyfikatory

DOI

10.18052/www.scipress.com/ILCPA.49.1

• Języki publikacji: EN

Abstrakty

EN

Totally thirty one 3,5-substituted aryl 4,5-dihydro isoxazole derivatives including 3-(2-naphthyl)-5-(substituted phenyl)-4,5-dihydroisoxazole have been synthesized by fly-ash:H₂SO₄ catalyzed cyclization of hydroxylamine hydrochloride and aryl chalcones under solvent-free conditions. The yields of the isoxazoles are more than 94%. The synthesized isoxazole were characterized by their physical constants and spectral data. The antimicrobial, antioxidant and insect antifeedant activities of the synthesized isoxazoles have been evaluated using a variety of bacterial and fungal species, DPPH radical scavenging and castor-leaf disc bioassay of 4th instar larvae Achoea Janata L methods.

Słowa kluczowe

EN

antimicrobial activity; antioxidant activity; dihydroisoxazole; Environmentally benign reaction; Insect antifeedant activity; NMR spectra

• Wydawca: Przedsiębiorstwo Wydawnictw Naukowych "DARWIN"
• Czasopismo: International Letters of Chemistry, Physics and Astronomy
• Rocznik: 2015
• Tom: Vol. 49
• Strony: 1--14
• Opis fizyczny: Bibliogr. 55 poz., rys., tab., wz.

Twórcy

autor

Thirunarayanan G.

• Department of Chemistry, Annamalai University, Annamalainagar-608 002, India

autor

Sathiyendiran V.

• Department of Chemistry, Sourashtra College, Madurai-625 004, India

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