Wykorzystanie pochodnych butano-2,3-diacetali w syntezie naturalnych związków optycznie czynnych

• Autorzy: Wacławczyk-Biedroń W. , Drop A. , Frąckowiak-Wojtasek B.

Warianty tytułu

EN

Application of butane-2,3-diacetals in the synthesis of optically active natural products

• Języki publikacji: PL EN

Abstrakty

PL

Butanodiacetale (BDA) są stabilnymi, optycznie czynnymi blokami budulcowymi wykorzystywanymi w syntezie produktów naturalnych. Otrzymać je można na drodze syntezy z tanich substratów: D-mannitolu, kwasu L-askorbinowego, L-winianu dimetylowego, oraz D-winianu dimetylowego. Usztywniona struktura butanodiacetali daje możliwość zastosowania ich w syntezie asymetrycznej. Przedstawiono przegląd literaturowy dotyczący syntezy butanodiacetali oraz ich zastosowania do syntezy małocząsteczkowych i wielkocząsteczkowych naturalnych związków optycznie czynnych.

EN

Butane diacetals (BDAs) are stable, optically active building blocks used in the synthesis of natural products. They can be synthesized from cheap substrates such as: D-mannitol, L-ascorbic acid, dimethyl L-tartrate and dimethyl D-tartrate. The rigid structure of butane diacetals makes possible their application in asymmetric synthesis. The article presents literature review on synthesis of butane diacetals and their application in the synthesis of natural small and large optically active compounds.

Słowa kluczowe

PL

związki naturalne; butano-2,3-diacetale; chiralne bloki budulcowe

EN

natural compounds; butane-2,3-diacetals; chiral building blocks

• Wydawca: Stowarzyszenie Inżynierów i Techników Przemysłu Chemicznego, ZW CHEMPRESS-SITPChem
• Czasopismo: Chemik
• Rocznik: 2014
• Tom: Vol. 68, nr 4
• Strony: 304--311
• Opis fizyczny: Bibliogr. 29 poz., rys.

Twórcy

autor

Wacławczyk-Biedroń W.

• Wydział Chemii, Uniwersytet Opolski, Opole

autor

Drop A.

• Wydział Chemii, Uniwersytet Opolski, Opole

autor

Frąckowiak-Wojtasek B.

• Wydział Chemii, Uniwersytet Opolski, Opole

Bibliografia

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