A structured mathematical model of PHA biopolymer production process

• Autorzy: Finkeová J , Hrnčiřík P , Mareš J. , Vovsik J , Hudeček O , Náhlík J
• Języki publikacji: EN

Abstrakty

EN

The paper describes a mathematical model of PHA biopolymer production process by Pseudomonas putida KT2442 where the octanoic acid is used as a substrate. The process is modeled using mass balances for fed-batch cultivation. Proper fitting to experimental data is obtained by identification of the model parameters. The model exhibits good agreement with experiments and its possible application for control is considered in the paper.

Słowa kluczowe

EN

mathematical model; fed-batch cultivation; biopolymer production; process identification; model verification; physiological situations; Pseudomonas putida KT2442

• Wydawca: Polish Academy of Sciences, Committee of Automatic Control and Robotics
• Czasopismo: Archives of Control Sciences
• Rocznik: 2013
• Tom: Vol. 23, no. 3
• Strony: 351--360
• Opis fizyczny: Bibliogr. 7 poz., rys., tab., wzory

Twórcy

autor

Finkeová J

• Department of Computing and Control Engineering, Institute of Chemical Technology, Prague, Technická 5. 166 28 Prague 6. Czech Republic

autor

Hrnčiřík P

• Department of Computing and Control Engineering, Institute of Chemical Technology, Prague, Technická 5. 166 28 Prague 6. Czech Republic

autor

Mareš J.

• Department of Computing and Control Engineering, Institute of Chemical Technology, Prague, Technická 5. 166 28 Prague 6. Czech Republic

autor

Vovsik J

• Department of Computing and Control Engineering, Institute of Chemical Technology, Prague, Technická 5. 166 28 Prague 6. Czech Republic

autor

Hudeček O

• Department of Computing and Control Engineering, Institute of Chemical Technology, Prague, Technická 5. 166 28 Prague 6. Czech Republic

autor

Náhlík J

• Department of Computing and Control Engineering, Institute of Chemical Technology, Prague, Technická 5. 166 28 Prague 6. Czech Republic

Bibliografia

• [1] M. H. Choi, J. Xu, J. K. Rho, X. P. Zhao and S. Ch. Yoon: Enhanced production of longer side-chain polyhydroxyalkanoic acid with ω-aromatic group substitution in phaZ-disrupted Pseudomonas fluorescens BM07 mutant through unrelated carbon source cometabolism and salicylic acid β-oxidation inhibition. BioresourceTechnology, 101(12), (2010), 4540-4548.
• [2] P. Hrnčiřík, J. Vovsík and J. Náhlík: A new on-line indicator of biopolymer content in bacterial cultures. In Proc. of 11th IFAC Symp. on Computer Applicationsin Biotechnology, Leuven, Belgium, (2010), 192-196.
• [3] P. Hrnčiřík, F. Černý , J. Náhlík, J. Vovsík, J. Mareš and P. Lovecká: Bioproduction of mcl-PHAs biopolymers - process states and control. In Proc. of18th Int. Conf. on Process Control, Tatransk´a Lomnica, Slovakia, (2011), 211-215.
• [4] G. C. Okpokwasili and C. O. Nweke: Microbial growth and substrate utilization kinetics. African J. Biotechnology, 5(4), (2005), 305-317.
• [5] P. Panand Y. Inoue: Polymorphism and isomorphism in biodegradable polyesters. Progress in Polymer Science, 34(7), (2009), 605-640.
• [6] S. Ray and C. A. Peters: Changes in microbiological metabolism under chemical stress. Chemosphere, 71(3), (2008), 474-483
• [7] Z. Suna, J. Ramsaya, M. Guaya and B. Ramsay: Enhanced yield of mediumchain- length polyhydroxyalkanoates from nonanoic acid by co-feeding glucose in carbon-limited, fed-batch culture. J. Biotechnology, 143(4), (2009), 262-267.