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The use of chemometrics to analyse protein patterns from gel electrophoresis

Identyfikatory
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Chemometrics involves strategies to analyse multivariate data using interdisciplinary approaches aiming to extract relevant information from complex data. Chemometric strategies comprise both the pre-processing of the data, where the choice of methodology is domain-specific, and analysis of the resulting data after preprocessing using multivariate methodology. Although use of multivariate data analysis for gel electrophoresis images has increased substantially in the last decade, its use is still much less frequent than use of univariate approaches. Considering the complexity of the electrophoresis gel images and the multivariate nature of the proteome, applying multivariate data analysis for gel electrophoresis images gives information which is otherwise lost. This paper is written as a review and guideline of chemometric strategies used for analysis of gel electrophoresis images. The multivariate data analyses described are, however, also relevant for other proteome data, for example mass spectrometry, and for functional genomics in general.
Rocznik
Strony
1--40
Opis fizyczny
Bibliogr. 258 poz., rys., tab.
Twórcy
  • Nofima Mat AS Osloveien 1 1430 Ås Norway
autor
  • NTNU 7491 Trondheim Norway
autor
  • Nofima Mat AS Osloveien 1 1430 Ås Norway
autor
  • Nofima Mat AS Osloveien 1 1430 Ås Norway
autor
  • University of Life Science Cigene PO Box 5003 1430 Ås Norway
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