Hybrid upconverting/paramagnetic Fe3O4/Gd2O3:Er3+, Yb3+, Mg2+, Nd3+ nanoparticles : synthesis, characterization and biological applications

• Autorzy: Kamińska Izabela , Sobczak Kamil , Zhydachevskyy Yaroslav , Wojciechowski Tomasz , Minikayev Roman , Sikora-Dobrowolska Bożena , Lewińska Sabina , Chojnacki Michał , Fronc Krzysztof

Identyfikatory

DOI

10.24425/opelre.2024.150182

• Języki publikacji: EN

Abstrakty

EN

The goals of this work are to design and develop a technology for fabrication and study of multifunctional properties of core/shell nanoparticles (NPs) as magnetic/luminescent markers. The new hybrid core/shell Fe₃O₄/Gd₂O₃:1% Er³+, 18% Yb³+, 2.5% Mg²+, x% Nd³+ NPs doped with different concentrations of neodymium ions, where x = 0%, 0.5%, 0.75%, 1%, 2%, 4%, were synthesized by the co-precipitation method. The NPs were characterised using XRD, TEM, SEM, EDX, confocal microscopy and photoluminescence. Fe₃O₄ (core) consists of several 13 nm NPs. The core/shell NPs have sizes from 220 nm to 641 nm. In this latter case, the shell thicknesses were 72, 80, and 121 nm. The upconversion efficiency properties and magnetic properties of the hybrid NPs were investigated. In the core/shell NPs, the addition of Nd³+ quenches the luminescence. The magnetic response of core/shell samples is rather paramagnetic and does not differ significantly from that registered for the shell material alone. For Gd₂O₃:1% Er³+, 18% Yb³+ and Fe₃O₄/Gd₂O₃:1% Er³+, 18% Yb³+, 2.5% Mg²+, 0.5% Nd³+, at 300 K, the values of the magnetization registered at ~ 40 kOe are similar and equal to ~ 5.3 emu·g⁻¹. The survivability of the HeLa tumor cells with the presence of the core/shell NPs was investigated for 24 h. The NPs are non-toxic up to a concentration of 1000 μg·ml⁻¹ and penetrate cells in the process of endocytosis which has been confirmed by confocal microscope studies.

Słowa kluczowe

EN

core/shell nanoparticles; upconversion; co-precipitation methods; HeLa tumor cells; confocal microscopy; paramagnetic

• Wydawca: Stowarzyszenie Elektryków Polskich ; Polska Akademia Nauk ; Wojskowa Akademia Techniczna im. Jarosława Dąbrowskiego
• Czasopismo: Opto-Electronics Review
• Rocznik: 2024
• Tom: Vol. 32, No. 2
• Strony: art. no. e150182
• Opis fizyczny: Bibliogr. 42 poz., rys., tab., wykr.

Twórcy

autor

Kamińska Izabela

• Institute of Physics, Polish Academy of Sciences, al. Lotników 32/46, Warsaw 02-668, Poland

• https://orcid.org/0000-0002-3386-6017

autor

Sobczak Kamil

• Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, ul. Żwirki i Wigury 101, Warsaw 02-089, Poland

autor

Zhydachevskyy Yaroslav

• Institute of Physics, Polish Academy of Sciences, al. Lotników 32/46, Warsaw 02-668, Poland

• https://orcid.org/0000-0003-4774-5977

autor

Wojciechowski Tomasz

• Institute of Physics, Polish Academy of Sciences, al. Lotników 32/46, Warsaw 02-668, Poland
• International Research Centre MagTop, al. Lotników 32/46, Warsaw 02-668, Poland

• https://orcid.org/0000-0002-6424-988X

autor

Minikayev Roman

• Institute of Physics, Polish Academy of Sciences, al. Lotników 32/46, Warsaw 02-668, Poland

• https://orcid.org/0000-0002-4334-7472

autor

Sikora-Dobrowolska Bożena

• Institute of Physics, Polish Academy of Sciences, al. Lotników 32/46, Warsaw 02-668, Poland

• https://orcid.org/0000-0001-5902-9682

autor

Lewińska Sabina

• Institute of Physics, Polish Academy of Sciences, al. Lotników 32/46, Warsaw 02-668, Poland

• https://orcid.org/0000-0003-0251-2694

autor

Chojnacki Michał

• Institute of Physics, Polish Academy of Sciences, al. Lotników 32/46, Warsaw 02-668, Poland
• International Research Centre MagTop, al. Lotników 32/46, Warsaw 02-668, Poland

• https://orcid.org/0000-0002-4475-1389

autor

Fronc Krzysztof

• Institute of Physics, Polish Academy of Sciences, al. Lotników 32/46, Warsaw 02-668, Poland
• International Research Centre MagTop, al. Lotników 32/46, Warsaw 02-668, Poland

• https://orcid.org/0000-0001-8279-8543

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2024).