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Diffuse reflectance spectroscopy for identification of carcinogen transformation stages in skin tissue

Identyfikatory
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Today, to establish a diagnosis, the patient must undergo a biopsy followed by histopathological diagnosis, which causes unnecessary cost, patient trauma, and time delay to obtain a diagnosis. However, the metastases can be discovered by diffuse reflectance spectroscopy, which is a simple method that investigates the light distribution within tissue. The theme of this paper is the use of diffuse reflectance spectroscopy (DRS) to determine the optical spectrum of hamster specimen’s tissue and to differentiate biological changes due to laser irradiation (scattering, and cell changes) under the skin. DRS measurements were made on healthy and malignant tissue to diagnose the stages of cancer formation using a fiber-optic probe. The results show that malignant tissue is characterized by a significant decrease in diffuse reflectance spectrum compared to normal tissue.
Rocznik
Strony
141--147
Opis fizyczny
Bibliogr. 17 poz., rys., tab.
Twórcy
  • Medical Physics, Biomedical Photonics Laboratory, Higher Institute for Laser Research and Applications, Damascus University, Damascus
  • Faculty of Dentistry, Al-Sham University, Damascus
autor
  • Biomedical Photonics Laboratory, Department of Laser Physics and Technology, Higher Institute for Laser Research and Applications, Damascus University, Damascus
Bibliografia
  • [1] Volynskaya Z, Haka AS, Bechtel Kl, et al. Diagnosing breast cancer using diffuse reflectance spectroscopy and intrinsic fluorescence spectroscopy. J Biomed Opt. 2008;13(2):024012-024012-9.
  • [2] Bigio IJ, Bown SG. Spectroscopic sensing of cancer and cancer chemotherapy, current status of translational research. Cancer Biol Ther. 2004;3(3):259-267.
  • [3] Flock ST, Jacques SL, Wilson BC, et al. Optical Properties of Intralipid:A Phantom Medium for Light Propagation Studies. Lasers Surg Med. 1992;12(5):510-519.
  • [4] Andersson A. Look-up table based Monte Carlo inverse model as a tool to discover liver tumors. Bachelor thesis. Lund University, 2015.
  • [5] Reif R, A’Amar O, Bigio IJ. Analytical model of light reflectance for extraction of the optical properties in small volumes of turbid media. Appl Opt. 2007;(46)29:7317-7328.
  • [6] van Veen RL, Amelink A, Menke-Pluymers M, et al. Optical biopsy of breast tissue using differential path-length spectroscopy. Phys Med Biol. 2005;50(11):2573-2581.
  • [7] Bigio IJ, Mourant JR. Optical Biopsy. In: Encyclopedia of Optical Engineering. Marcel Dekker Press, 2003.
  • [8] Alhamami M. Photoacoustic Detection and Optical Spectroscopy of High-Intensity Focused Ultrasound-Induced Thermal Lesions in Biologic Tissue. Master thesis. Ryerson University, 2013.
  • [9] Jacques SL. Corrigendum: Optical properties of biological tissues: a review. Phys Med Biol. 2012;58:5007.
  • [10] Yaroslavsky AN, Schulze PC, Yaroslavsky IV, et al. Optical properties of selected native and coagulated human brain tissues in vitro in the visible and near infrared spectral range. Phys Med Biol. 2002;47(12):2059-2073
  • [11] Friebel M, Roggan A, Mueller G, Meinke M. Determination of optical properties of human blood in the spectral range 250 to 1100 nm using Monte Carlo simulations with hematocrit-dependent effective scattering phase functions. J Biomed Opt. 2006;11(3):34021.
  • [12] Romanos GE, Henze M, Banihashemi S, et al. Removal of epithelium in periodontal pockets following diode (980 nm) laser application in the animal model: an in vitro study. Photomed Laser Surg. 2004;22(3):177-183.
  • [13] Anderson RR. Lasers in Dermatology – A Critical Update. J Dermat. 2000;27(11):700-705.
  • [14] Sozzi M, Fornaini C, Cucinotta C, et al. Dental ablation with 1064 nm, 500 ps, Diode pumped solid state laser: A preliminary study. Laser Ther. 2013;22(3)195-199.
  • [15] Sugimura T. Studies on environmental chemical carcinogenesis in Japan. Science. 1986;233(4761):312-318.
  • [16] Shubik P, Pietra G, Della Porta G. Studies of Skin Carcinogenesis in the Syrian Golden Hamster. Cancer Res. 1960;20:100-105.
  • [17] Einstein G, Udayakumar K, Arun PR, et al. Diffuse reflectance spectroscopy for monitoring physiological and morphological changes in oral cancer. Optik. 2016;127(3):1479-1485.
Uwagi
Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2020).
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-4f9f1101-d887-4433-bb74-944288d621f0
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