Effects of aortic valve diseases on pressure profiles in selected locations of the human arterial system

• Autorzy: Majka M. , Gadda G. , Taibi A. , Zieliński P.

Identyfikatory

DOI

10.4467/2353737XCT.17.223.7766

Warianty tytułu

PL

Wpływ chorób zastawki aortalnej na przebiegi ciśnienia w wybranych miejscach układu tętniczego człowieka

• Języki publikacji: EN

Abstrakty

EN

Aortic valve diseases such as aortic stenosis and aortic regurgitation, are the most frequent valvular heart diseases. The lesions in the valves affect circulation in the whole arterial system. We study the effects with the use of a 1-D model in which an arterial segment transmits a single mode of pulse waves. The appropriate reflection coefficient and the form of the stroke pressure are devised to simulate the function of the healthy and morbid aortic valve. The time dependence of the arterial pressure is predicted at the most important locations of the arterial tree. A remarkable result is that little variations of the reflection coefficient of the vale due to the modelled diseases cause significant changes of the pressure profiles, especially at the ascending aorta, the left brachial artery and in the anterior communicating artery.

PL

Zwężenie zastawki aortalnej (stenosis ostii arteriosi sinistri) oraz niedomykalność zastawki aortalnej (insufficientia valvulae aortae) są najczęstszymi chorobami zastawek serca. Zmiany chorobowe zastawki niewątpliwie wpływają na obieg krwi w całym układzie tętniczym. Wpływ tych zmian zbadano przy użyciu jednowymiarowego modelu, w którym każdy segment tętnicy transmituje tylko jeden mod fali tętna. Opracowane odpowiednie wartości współczynnika odbicia zastawki aortalnej oraz kształt ciśnienia generowanego przy skurczu serca symulują realistycznie działanie zastawki zdrowej i chorej. Otrzymane wyniki pozwalają przewidywać przebiegi ciśnienia w najistotniejszych miejscach drzewa tętniczego. Zadziwiający jest fakt, że nawet najmniejsze różnice w współczynniku odbicia od zastawki powodują znaczące zmiany w profilach ciśnienia, a w szczególności w aorcie wstępującej, lewej tętnicy ramiennej oraz w tętnicy łączącej przedniej.

Słowa kluczowe

EN

arterial model; aortic valve diseases; aortic stenosis; aortic regurgitation; transmission line; pressure profiles; Circle of Willis

PL

model tętniczy; choroba zastawki aortalnej; zwężenie zastawki aortalnej; niedomykalność zastawki aortalnej; linia transmisyjna; przebieg ciśnienia; koło Willisa

• Wydawca: Wydawnictwo Politechniki Krakowskiej im. Tadeusza Kościuszki
• Czasopismo: Technical Transactions
• Rocznik: 2017
• Tom: Vol. 12(114)
• Strony: 243--255
• Opis fizyczny: Bibliogr. 37 poz., il., wz., wykr.

Twórcy

autor

Majka M.

• The Henryk Niewodniczański Institute of Nuclear Physics Polish Academy of Sciences

autor

Gadda G.

• Department of Physics and Earth Sciences, University of Ferrara

autor

Taibi A.

• Department of Physics and Earth Sciences, University of Ferrara

autor

Zieliński P.

• Institute of Physics, Cracow University of Technology

Bibliografia

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Uwagi

EN

Section "Physics"

PL

Opracowanie ze środków MNiSW w ramach umowy 812/P-DUN/2016 na działalność upowszechniającą naukę (zadania 2017)