Nanostructure of bovine pericardium treated with trypsin

• Autorzy: Turek A. , Marcinkowski A. , Trzebicka B. , Cwalina B. , Dzierżewicz Z.
• Języki publikacji: EN

Abstrakty

EN

Various methods of xenogeneic tissues stabilization have been proposed for the purpose of preparing many tissue-derived biomaterials. One of the most important treatments that may lead to obtaining the good-quality tissue biomaterials seems to be decellularization of such tissues. This process may contribute to the reduction of the most frequent failures resulting from the tissues stabilization. The aim of this work was to determine nanostructure of trypsin-treated bovine pericardium, using atomic force microscopy (AFM). The treatment of bovine pericardium with trypsin in EDTA solution resulted in non significant changes in tissue’s morphology. Demonstrated AFM studies of these tissues revealed no failures on the fibers’ surface in the nanoscale. Thus, our results confirm the expec-tation that decellularization may be considered as one of the most promising methods of the allogeneic and xenogeneic tissues stabilization.

Słowa kluczowe

EN

nanostructure; bovine pericardium (BP); collagen fibers; trypsin

• Wydawca: Polish Society for Biomaterials in Cracow
• Czasopismo: Engineering of Biomaterials
• Rocznik: 2009
• Tom: Vol. 12, no. 89-91
• Strony: 30--32
• Opis fizyczny: Bibliogr. 15 poz., wykr., zdj.

Twórcy

autor

Turek A.

• Department of Biopharmacy, Medical University of Silesia, Sosnowiec, Poland

autor

Marcinkowski A.

• Centre of Polymer and Carbon Materials, Polish Academy of Science, Zabrze, Poland

autor

Trzebicka B.

• Centre of Polymer and Carbon Materials, Polish Academy of Science, Zabrze, Poland

autor

Cwalina B.

• Department of Environmental Biotechnology, Silesian University of Technology, Gliwice, Poland

autor

Dzierżewicz Z.

• Department of Biopharmacy, Medical University of Silesia, Sosnowiec, Poland

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