Reactor Laboratory for Biomedical Research in National Centre for Nuclear Research in Poland

• Autorzy: Michaś Edyta , Dorosz Michał , Wójciuk Karolina , Tymińska Katarzyna , Wiliński Maciej , Maciak Maciej , Domański Szymon , Wojtania Grzegorz , Bartosik Łukasz , Małkiewicz Adam , Lechniak Jan , Gryziński Michał Aleksander

Identyfikatory

DOI

10.2478/pjmpe-2021-0014

• Języki publikacji: EN

Abstrakty

EN

National Centre for Nuclear Research, NCBJ is one of the biggest research institutes in Poland, in which scientists deal with basic research in the various fields of subatomic physics, development of nuclear technologies and practical applications of nuclear physics methods, including those for nuclear medicine and radiotherapy. NCBJ operates the only Polish nuclear research reactor MARIA, around which a Reactor Laboratory for Biomedical Research, RLBR has been built in the last 4 years. One of the main aims of the RLBR team is to adapt the H2 channel, one of the eight MARIA’s horizontal channels, to a specific irradiation facility delivering a high flux thermal/epithermal neutron beam. The beam derived from the channel will be a tool for biological, physical and material studies for Boron Neutron Capture Therapy, BNCT. While NCBJ is focused on building a neutron research facility, the Polish scientific community expressed its interest in BNCT development and implementation as an alternative therapy for cancer treatment. Through the working group meetings organized in the form of regular scientific workshops since 2015, it led to the establishment of a national scientific consortium dedicated to BNCT. Polish Consortium for Boron Neutron Capture Therapy agreement was initially signed by twelve institutions including scientific institutes, universities and oncological centres in October 2019. National Centre for Nuclear Research was appointed the leader of the consortium. A year later the consortium was enlarged by two more institutions.

Słowa kluczowe

EN

BNCT; radiobiology; radiochemistry; neutron beams; research reactor

• Wydawca: Polskie Towarzystwo Fizyki Medycznej ; De Gruyter
• Czasopismo: Polish Journal of Medical Physics and Engineering
• Rocznik: 2021
• Tom: Vol. 27, Iss. 1
• Strony: 119--122
• Opis fizyczny: Bibliogr. 12 poz., rys.

Twórcy

autor

Michaś Edyta

• National Centre for Nuclear Research, Andrzeja Soltana 7, 05-400 Otwock, Poland

autor

Dorosz Michał

• National Centre for Nuclear Research, Andrzeja Soltana 7, 05-400 Otwock, Poland

autor

Wójciuk Karolina

• National Centre for Nuclear Research, Andrzeja Soltana 7, 05-400 Otwock, Poland

autor

Tymińska Katarzyna

• National Centre for Nuclear Research, Andrzeja Soltana 7, 05-400 Otwock, Poland

autor

Wiliński Maciej

• National Centre for Nuclear Research, Andrzeja Soltana 7, 05-400 Otwock, Poland

autor

Maciak Maciej

• National Centre for Nuclear Research, Andrzeja Soltana 7, 05-400 Otwock, Poland

autor

Domański Szymon

• National Centre for Nuclear Research, Andrzeja Soltana 7, 05-400 Otwock, Poland

autor

Wojtania Grzegorz

• National Centre for Nuclear Research, Andrzeja Soltana 7, 05-400 Otwock, Poland

autor

Bartosik Łukasz

• National Centre for Nuclear Research, Andrzeja Soltana 7, 05-400 Otwock, Poland

autor

Małkiewicz Adam

• National Centre for Nuclear Research, Andrzeja Soltana 7, 05-400 Otwock, Poland

autor

Lechniak Jan

• National Centre for Nuclear Research, Andrzeja Soltana 7, 05-400 Otwock, Poland

autor

Gryziński Michał Aleksander

• National Centre for Nuclear Research, Andrzeja Soltana 7, 05-400 Otwock, Poland

Bibliografia

• 1. Gryzinski MA, Maciak M, Wielgosz M. Summary of recent BNCT Polish programme and future plans. Appl Radiat Isot. 2015;106:10-17. https://doi.org/10.1016/j.apradiso.2015.07.047
• 2. Autodesk. Autodesk Inventor Professional. Autodesk; 2018.
• 3. Jakubowska E, Golnik N, Gryzinski M, Tulik P. Application of recombination chambers for determination of neutron ambient dose equivalent at the door to the maze of linear accelerator vault. Polish Journal of Medical Physics and Engineering. 2011;17(3):153-158. https://doi.org/10.2478/v10013-011-0015-2
• 4. Tulik P, Tulik M, Maciak M, et al. Investigation of secondary mixed radiation field around a medical linear accelerator. Radiat Prot Dosimetry. 2018;180(1-4):252-255. doi:10.1093/rpd/ncx199
• 5. Golnik N, Mayer S, Zielczynski M. Recombination index of radiation quality of low-LET radiation. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 2004;213:650-653. https://doi.org/10.1016/S0168-583X(03)01679-3
• 6. Tulik P, Lepak S, Domańska K, Jakubowska EA. Characterization of low-LET radiation fields for irradiation of biological samples using recombination chamber. In: Jabłoński R., Brezina T. (eds) Advanced Mechatronics Solutions. Advances in Intelligent Systems and Computing, vol 393. Springer, Cham. 2016. https://doi.org/10.1007/978-3-319-23923-1_20
• 7. Jakubowska E, Zielczynski M, Golnik N, Gryzinski MA, Krzeminski L. A ring-shaped recombination chamber for hadron therapy dosimetry. Radiat Prot Dosimetry. 2014;161(1-4):201–204. https://doi.org/10.1093/rpd/nct355
• 8. Jakubowska EA, Gryziński MA, Golnik N, et al. Ambient dose equivalent measurements in secondary radiation fields at proton therapy facility CCB IFJ PAN in Krakow using recombination chambers. Nukleonika. 2016;61(1):23-28. https://doi.org/10.1515/nuka-2016-0006
• 9. Tulik P, Golnik N, Zielczynski M. Recombination chambers filled with different gases–studies of possible application for BNCT beam dosimetry. Radiat Prot Dosimetry. 2004;110(1-4):669-673. https://doi.org/10.1093/rpd/nch160
• 10. Tulik P, Golnik N, Zielczynski M. Investigations of recombination chambers for BNCT beam dosimetry. Radiat Prot Dosimetry. 2007;126(1-4):648-651. https://doi.org/10.1093/rpd/ncm131
• 11. Tulik P, Golnik N. Studies of recombination chambers filled with nitrogen for BNCT dosimetry. Nukleonika. 2009;54(4):255-259.
• 12. Tulik P, Kowalska M, Golnik N, Budzynska A, Dziuk M. Measurements of the ionising radiation level at a nuclear medicine facility performing PET/CT examinations. Radiat Prot Dosimetry. 2017;174(4):501–509. https://doi.org/10.1093/rpd/ncw228

Uwagi

Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2021).