An efficient one-pot multicomponent synthesis and characterization of 5-cyano-1,2,3,4-tetrahydropyrimidine derivatives

• Autorzy: Vaghasiya R. G. , Shah V. H.

Identyfikatory

DOI

10.18052/www.scipress.com/ILCPA.40.51

• Języki publikacji: EN

Abstrakty

EN

A series of pyrimidine-5-carbonitrile derivatives was efficiently synthesized via one-pot, multi component reaction (MCRs) of 1,3-bifunctional synthon (ethylcyano acetate), substituted pyrazole-4-carbaldehyde, and thiourea/urea in the presence of basic catalyst. The key advantages of this process are high yields, shorter reaction times, easy work-up, and purification of products by non-chromatographic method.

Słowa kluczowe

EN

substituted pyrazole-4-carbaldehyde; 5-cyano-1,2,3,4-tetrahydropyrimidine derivatives; multi component reaction; non-chromatographic method

• Wydawca: Przedsiębiorstwo Wydawnictw Naukowych "DARWIN"
• Czasopismo: International Letters of Chemistry, Physics and Astronomy
• Rocznik: 2015
• Tom: Vol. 40
• Strony: 51--60
• Opis fizyczny: Bibliogr. 24 poz., rys., tab., wz.

Twórcy

autor

Vaghasiya R. G.

• Department of Chemistry, Saurashtra University, University Road, Rajkot - 360 005, Gujarat, India

autor

Shah V. H.

• Department of Chemistry, Saurashtra University, University Road, Rajkot - 360 005, Gujarat, India

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