Ekstrakcja micelarna cymetydyny

• Autorzy: Kiszkiel-Taudul I.

Warianty tytułu

EN

Micellar extraction of cimetidine

• Języki publikacji: PL EN

Abstrakty

PL

W pracy przedstawiono procedurę ekstrakcji micelarnej cymetydyny (CMT) w celu efektywnego jej wydzielenia z próbki wodnej. Badany związek należy do grupy leków przeciwhistaminowych i jest szeroko stosowany w terapii schorzeń układu pokarmowego. W przeprowadzonych badaniach, ekstrakcję micelarną CMT przeprowadzono z udziałem dwóch surfaktantów: dodecylosiarczanu-(VI) sodu (SDS) oraz Tween-u 80 (TW-80). Wyznaczono parametry analityczne spektrofotometrycznych metod oznaczania cymetydyny w zakresie UV. Opracowane procedury zastosowano do sprawdzenia obecności badanego analitu w próbkach naturalnych.

EN

The presented paper describes an elaboration of micellar extraction procedures for effective isolation of cimetidine (CMT) from aqueous samples. This antihistamine drug is widely applied for treatment diseases of stomach. The micellar extraction of cimetidine was performed with using sodium dodecylsulfate(VI) and Tween-80 (TW-80). The analytical parameters of spectrophotometric (UV) determination of the studied compound were calculated. The elaborated methods following by micellar extraction procedures were used for the analysis of cimetidine in natural water samples.

Słowa kluczowe

PL

cymetydyna; ekstrakcja micelarna; SDS; Tween-80; analiza wód powierzchniowych

EN

cimetidine; micellar extraction; SDS; Tween-80; surface water analysis

• Wydawca: Stowarzyszenie Inżynierów i Techników Przemysłu Chemicznego, ZW CHEMPRESS-SITPChem
• Czasopismo: Chemik
• Rocznik: 2016
• Tom: Vol. 70, nr 2
• Strony: 105--110
• Opis fizyczny: Bibliogr. 19 poz., rys., tab.

Twórcy

autor

Kiszkiel-Taudul I.

• Instytut Chemii, Uniwersytet w Białymstoku, Białystok

Bibliografia

• 1. Petrović M., Škrbić B., Živančev J., Ferrando-Climent L., Barcelo D.: Determination of 81 pharmaceutical drugs by high performance liquid chromatography coupled to mass spectrometry with hybrid triple quadrupole–linear ion trap in different types of water in Serbia. Science of the Total Environment 2014, 468–469, 415–428.
• 2. Dong Z., Senn D.B., Moran R.E., Shine J.P.: Prioritizing environmental risk of prescription pharmaceuticals. Regulatory Toxicology and Pharmacology 2013, 65, 60–67.
• 3. Orias F., Perrodin Y.: Characterisation of the ecotoxicity of hospital effluents: A review. Science of the Total Environment 2013, 454–455, 250–276.
• 4. Sultana M., Saeed Arayne M., Shamshad H.: In vitro studies of the interaction between cetirizine and H2 receptor antagonists using spectrophotometry and reversed-phase high-performance liquid chromatography. Medicinal Chemistry Research 2010, 19, 462–474.
• 5. Sun X., Tian Y., Zhang Z., Chen Y.: A single LC–tandem mass spectrometry method for the simultaneous determination of four H2 antagonists in human plasma. Journal of Chromatography B 2009, 877, 3953–3959.
• 6. Darwish I.A., Hussein S.A., Mahmoud A.M., Hassan A.I.: Spectrophotometric determination of H2-receptor antagonists via their oxidation with cerium(IV). Spectrochimica Acta Part A 2008, 69, 33–40.
• 7. Sayin U.: EPR analysis of gamma irradiated single crystal cimetidine. Journal of Molecular Structure 2013, 1031, 132–137.
• 8. Dolores-Hernando M., José-Gómez M., Agüera A., Fernández-Alba A.R.: LCMS analysis of basic pharmaceuticals (beta-blockers and anti-ulcer agents) in wastewater and surface water. Trends in Analytical Chemistry 2007, 26, 581–594.
• 9. Tirmizi S.A., Wattoo F.H., Sarwar-Wattoo M.H., Sarwar S., Memon A.N., Ghangro A.B.: Spectrophotometric study of stability constants of cimetidine–Ni(II) complex at different temperatures. Arabian Journal of Chemistry 2012, 5, 309–314.
• 10. Feng Y., Li X., Xu K., Zou H., Li H., Liang B.: Qualitative and simultaneous quantitative analysis of cimetidinepolymorphs by ultraviolet–visible and shortwave near-infrareddiffuse reflectance spectroscopy and multivariate calibration models. Journal of Pharmaceutical and Biomedical Analysis 2015, 104, 112–121.
• 11. Iqbal T., Karyekar C.S., Kinjo M., Ngan G.C., Dowling T.C.: Validation of a simplified method for determination of cimetidine in human plasma and urine by liquid chromatography with ultraviolet detection. Journal of Chromatography B 2004, 799, 337–341.
• 12. Varga R., Somogyvári I., Eke Z., Torkos K.: Determination of antihypertensive and anti-ulcer agents from surface water with solid-phase extraction–liquid chromatography–electrospray ionization tandem mass spectrometry. Talanta 2011, 83, 1447–1454.
• 13. Choi K., Kim Y., Park J., Park C.K., Kim M., Kim H.S., Kim P.: Seasonal variations of several pharmaceutical residues in surface water and sewage treatment plants of Han River, Korea. Science of the Total Environment 2008, 405, 120–128.
• 14. Candir S., Narin I., Soylak M.: Ligandless cloud point extraction of Cr(III), Pb(II), Cu(II), Ni(II), Bi(III), and Cd(II) ions in environmental samples with Tween 80 and flame atomic absorption spectrometric determination. Talanta 2008, 77, 289–293.
• 15. Carabias-Martínez R., Rodríguez-Gonzalo E., Moreno-Cordero B., Pérez-Pavón J.L., García-Pinto C., Fernández-Laespada E.: Surfactant cloud point extraction and preconcentration of organic compounds prior to chromatography and capillary electrophoresis. Journal of Chromatography A 2000, 902, 251–265.
• 16. Paleologos E.K., Giokas D.L., Karayannis M.I.: Micelle-mediated separation and cloud-point extraction. Trends in Analytical Chemistry 2005, 24, 426–436.
• 17. Xing W., Chen L.: Micelle-mediated extraction and cloud point preconcentration of bergenin from Ardisia japonica. Separation and Purification Technology 2013, 110, 57–62.
• 18. Raducan A., Olteanu A., Puiu M., Oancea D.: Influence of surfactants on the fading of malachite green. Central European Journal of Chemistry 2008, 6, 89–92.
• 19. Mahajan R.K., Chawla J., Bakshi M.S.: Effects of monomeric and polymeric glycol additives on micellar properties of Tween non-ionic surfactants as studied by cyclic voltammetry. Colloids and Surfaces A: Physicochem. Eng. Aspects 2004, 237, 119–124.

Uwagi

Opracowanie ze środków MNiSW w ramach umowy 812/P-DUN/2016 na działalność upowszechniającą naukę.