Assessment of High Frequency Imaging and Doppler System for the Measurements of the Radial Artery Flow-Mediated Dilation

• Autorzy: Nowicki Andrzej , Gambin Barbara , Secomski Wojciech , Trawiński Zbigniew , Szubielski Michał , Tymkiewicz Ryszard , Olszewski Robert

Identyfikatory

DOI

10.24425/aoa.2019.129276

• Języki publikacji: EN

Abstrakty

EN

Objectives: In the article we describe the new, high frequency, 20 MHz scanning/Doppler probe designed to measure the flow mediated dilation (FMD) and shear rate (SR) close to the radial artery wall. Methods: We compare two US scanning systems, standard vascular modality working below 12 MHz and high frequency 20 MHz system designed for FMD and SR measurements. Axial resolutions of both systems were compared by imaging of two closely spaced food plastic foils immersed in water and by measuring systolic/diastolic diameter changes in the radial artery. The sensitivities of Doppler modalities were also determined. The diagnostic potential of a high frequency system in measurements of FMD and SR was studied in vivo, in two groups of subjects, 12 healthy volunteers and 14 patients with stable coronary artery disease (CAD). Results: Over three times better axial resolution was demonstrated for a high frequency system. Also, the sensitivity of the external single transducer 20 MHz pulse Doppler proved to be over 20 dB better (in terms of a signal-to-noise ratio) than the pulse Doppler incorporated into the linear array. Statistically significant differences in FMD and FMD/SR values for healthy volunteers and CAD patients were confirmed, p-values < 0:05. The areas under Receiver Operating Characteristic (ROC) curves for FMD and FMD/SR for the prediction CAD had the values of 0.99 and 0.97, respectively. Conclusions: These results justify the usefulness of the designed high-frequency scanning system to determine the FMD and SR in the radial artery as predictors of coronary arterial disease.

Słowa kluczowe

EN

flow mediated dilation; shear rate; axial resolution; elevation resolution; pulsed Doppler; ultrasonic imaging

• Wydawca: Instytut Podstawowych Problemów Techniki PAN ; Komitet Akustyki PAN ; Polskie Towarzystwo Akustyczne
• Czasopismo: Archives of Acoustics
• Rocznik: 2019
• Tom: Vol. 44, No. 4
• Strony: 637--644
• Opis fizyczny: Bibliogr. 16 poz., fot., rys., wykr.

Twórcy

autor

Nowicki Andrzej

• Institute of the Fundamental Technological Research, Polish Academy of Sciences, Pawińskiego 5B, 02-106 Warsaw, Poland

autor

Gambin Barbara

• Institute of the Fundamental Technological Research, Polish Academy of Sciences, Pawińskiego 5B, 02-106 Warsaw, Poland

autor

Secomski Wojciech

• Institute of the Fundamental Technological Research, Polish Academy of Sciences, Pawińskiego 5B, 02-106 Warsaw, Poland

autor

Trawiński Zbigniew

• Institute of the Fundamental Technological Research, Polish Academy of Sciences, Pawińskiego 5B, 02-106 Warsaw, Poland

autor

Szubielski Michał

• Mazovia Regional Hospital in Siedlce, Siedlce, Poland

autor

Tymkiewicz Ryszard

• Institute of the Fundamental Technological Research, Polish Academy of Sciences, Pawińskiego 5B, 02-106 Warsaw, Poland

autor

Olszewski Robert

• Institute of the Fundamental Technological Research, Polish Academy of Sciences, Pawińskiego 5B, 02-106 Warsaw, Poland
• Department of Gerontology, Public Health and Didactics, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland

Bibliografia

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2020).