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Fabrication of filter membrane of organic compound to protect the upper respiratory tract from viral and bacterial infections, including SARS-CoV-2, compliant with FFP2 standard

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Bacteria, viruses, and other pathogens in the surrounding environment are biological threat to human health and life. The development of various diseases in the world, as well as the pandemic caused by the rapid spread of the SARS-CoV-2 virus, have increased the demand for the use of upper respiratory protection devices. Out of concern for the natural environment, the aim of this work was to develop an innovative solution i.e. the FFP3 filtering membrane made of an organic compound. First, preliminary tests of the FFP2 mask were carried out to assess the chemical composition, morphological structure - fibers geometry, thickness, density, and arrangement. The FTIR analysis study was conducted to confirm that the main chemical in the mask was polypropylene (PP) and high-density polyethylene (HDPE). Optical, confocal microscopy and computer microtomography studies showed the fibers structure. They were densely arranged and their thickness was less than 1 den. The fiber structure of the FFP2 mask was also compared before and after immersing in betulin, an organic compound obtained from birch bark via the Soxhlet extraction. In addition, the assessment of microbiological activity was made on the reference strain Escherichia coli ATCC 25922, and the anti-inflammatory activity on normal human skin fibroblasts on polycarbonate with betulin. The studies showed that betulin supported the material antibacterial and anti-inflammatory properties.
Rocznik
Strony
2--11
Opis fizyczny
Bibliogr. 20 poz., rys., wykr.
Twórcy
  • Faculty of Science and Technology, University of Silesia, 75 Pułku Piechoty 1A, 41-500 Chorzów, Poland
autor
  • Faculty of Science and Technology, University of Silesia, 75 Pułku Piechoty 1A, 41-500 Chorzów, Poland
  • Faculty of Science and Technology, University of Silesia, 75 Pułku Piechoty 1A, 41-500 Chorzów, Poland
  • Institute of Sport Science, The Jerzy Kukuczka Academy of Physical Education, Mikołowska 72A, 40-065 Katowice, Poland
  • Faculty of Science and Technology, University of Silesia, 75 Pułku Piechoty 1A, 41-500 Chorzów, Poland
  • Faculty of Science and Technology, University of Silesia, 75 Pułku Piechoty 1A, 41-500 Chorzów, Poland
  • Faculty of Science and Technology, University of Silesia, 75 Pułku Piechoty 1A, 41-500 Chorzów, Poland
  • Institute of Sport Science, The Jerzy Kukuczka Academy of Physical Education, Mikołowska 72A, 40-065 Katowice, Poland
Bibliografia
  • [1] Regli A., Sommerfield A., Ungern-Sternberg B.S.: The role of fit testing N95/FFP2/FFP3 masks: a narrative review. Anaesthesia 76(1) (2021) 91-100, doi: 10.1111/anae.15261
  • [2] Cascella M., Rajnik M., Aleem A., et al.: Features, Evaluation, and Treatment of Coronavirus (COVID-19). StatPearls Publishing (2021)
  • [3] Nowakowska E., Michalak S.S.: Covid-19 – Choroba wywołana zakażeniem wirusem SARS-Cov-2 globalnym zagrożeniem dla zdrowia publicznego. Postępy Mikrobiologii – Advancements of Microbiology 59(3) (2020) 227-236, doi: 10.21307/pm-2020.59.3.16
  • [4] Pawlik L., Śpiołek E., Fichna J., Tarasiuk A.: Charakterystyka wirusa SARS-CoV-2 i potencjalne farmakologiczne sposoby leczenia. Postępy Biochemii: Zakład Biochemii, Katedra Chemii i Biochemii Medycznej, Uniwersytet Medyczny w Łodzi 66(2) (2020), doi: 10.18388/pb.2020_321
  • [5] Fenner F.: Epidemiology and Evolution. In: Baron S., editor. Medical Microbiology. 4th edition. Galveston (TX): University of Texas Medical Branch at Galveston (1996)
  • [6] Tcharkhtchi A., Abbasnezhad N., Zarbini Seydan M. et al.: An overview of filtration efficiency through the masks: Mechanisms of the aerosols penetration. Bioactive Materials 6(1) (2021) 106-122, doi: 10.1016/j.bioactmat.2020.08.002
  • [7] Ippolito M., Vitale F., Accurso G. et al.: Medical masks and Respirators for the Protection of Healthcare Workers from SARSCoV-2 and other viruses. Pulmonology 26(4) (2020) 204-212, doi: 10.1016/j.pulmoe.2020.04.009
  • [8] Smereka J., Ruetzler K. et al: Role of Mask/Respirator Protection Against SARS-CoV-2. Anesthesia and analgesia 131(1) (2020) e33-e34, doi:10.1213/ANE.0000000000004873
  • [9] Zhou J., Hu Z., Zabihi F. et al.: Progress and Perspective of Antiviral Protective Material. Advanced Fiber Materials 2 (2020) 123-139, doi: 10.1007/s42765-020-00047-7
  • [10] Li K.K.W., Joussen A.M., Kwan J.K.C. et al.: FFP3, FFP2, N95, surgical masks and respirators: what should we be wearing for ophthalmic surgery in the COVID-19 pandemic? Graefes Arch Clin Exp Ophthalmol. 258(8) (2020) 1587-1589, doi: 10.1007/ s00417-020-04751-3
  • [11] Palaniappan P., Sathishkumar G., Sankar R.: Fabrication of nano-silver particles using Cymodocea serrulata and its cytotoxicity effect against human lung cancer A549 cells line, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 138 (2015) 885-890 doi: https://doi.org/10.1016/j.saa.2014.10.072.
  • [12] Massarsky A., Abraham R., Nguyen K.C. et al.: Nanosilver cytotoxicity in rainbow trout (Oncorhynchus mykiss) erythrocytes and hepatocytes. Comp. Biochem. Physiol. Pt. C. 159 (2014) 10-21.
  • [13] Swinarew A., Boryczka S., Mazurek U. et al.: Modyfikowany polimer termoplastyczny o właściwościach przeciwbakteryjnych i przeciwzapalnych oraz sposób jego otrzymywania, Polska, 422092 B1, 03.07.2017
  • [14] Tolstikova T.G., Sorokina I.V., Tolstikov G.A. et al.: Biological activity and pharmacological prospects of lupane terpenoids: II. Semisynthetic lupane derivatives. Chem. 32 (2006) 37-49.
  • [15] Huang T., Li D., Elc M., Water repellency improvement of cellulosic textile fibers by betulin and a betulin-based copolymer. Cellulose 25, 2115-2128 (2018), doi: https://doi.org/10.1007/ s10570-018-1695-5.
  • [16] Alakurtti S., Mäkelä T., Koskimies S., et al.: Pharmacological properties of the ubiquitous natural product betulin. Eur J Pharm Sci. 29(1) (2006) 1-13.
  • [17] Kowalczuk D., Pitucha M.: Application of FTIR Method for the Assessment of Immobilization of Active Substances in the Matrix of Biomedical Materials. Materials (Basel) 12(18) (2019) 2972, doi: 10.3390/ma12182972;
  • [18] Pulit J., Banach M., Kowalski Z.: Właściwości nanocząsteczek miedzi, platyny, srebra, złota i palladu. Czasopismo techniczne, Wydawnictwo Politechniki Krakowskiej 10 (2011)
  • [19] Massarsky A., Abraham R., Nguyen K.C. et al.: Nanosilver cytotoxicity in rainbow trout (Oncorhynchus mykiss) erythrocytes and hepatocytes. Comp. Biochem. Physiol. Pt. C. 159 (2014) 10-21.
  • [20] Brown R.C.: Effect of electric charge in filter materials. Filtration & Separation 26(1) (1989) 46-51, doi: 10.1016/S0015- 1882(89)80057-6.
Uwagi
Opracowanie rekordu ze środków MEiN, umowa nr SONP/SP/546092/2022 w ramach programu „Społeczna odpowiedzialność nauki” - moduł: Popularyzacja nauki i promocja sportu (2022-2023)
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-402c2013-9262-4bd7-a247-e101640a55f4
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