Aktywność ozonowanej oliwy z oliwek przy zwalczaniu drobnoustrojów

• Autorzy: Nocuń M. , Krzyściak P. , Niedźwiedzka E. , Niedźwiedzki J. , Krzyściak-Kosińska R.

Warianty tytułu

EN

Antimicrobial activity of ozonized olive oil

• Języki publikacji: PL EN

Abstrakty

PL

Ozonowana oliwa z oliwek wspomaga gojenie się ran i wykazuje działanie przeciwdrobnoustrojowe. Oceniono skuteczność ozonowanej oliwy z oliwek z własnej syntezy przeciwko zwykłym bakteriom (Staphylococcus aureus, Escherichia coli, Klebisella pneumoniae i Pseudomonas aeruginosa) oraz grzybom (Candida albicans, Malassezia globosa, Aspergillus niger, Aspergillus fumigatus i Trichophyton mentagrophytes). Do oceny aktywności przeciwdrobnoustrojowej wykorzystano zarówno metodę mikrorozcieńczeń, jak i mikrodyfuzję w agarze. Minimalne stężenia ozonowanej oliwy z oliwek, które hamowały wzrost wszystkich badanych bakterii i grzybów, wynosiły odpowiednio 0,8% i 3,12%. Badania cytotoksyczności z użyciem mysich fibroblastów zarodkowych wskazują, że ozonowana oliwa z oliwek ma niski efekt cytopatyczny do stężenia 6,25%. Ozonowane oleje roślinne wykazują dobrą skuteczność przeciwdrobnoustrojową i niską cytotoksyczność. Konieczne jest jednak opracowanie standardowej metodologii umożliwiającej międzylaboratoryjne porównywanie wyników.

EN

Ozonized olive oil supports healing wounds and shows antimicrobial action. The efficacy of self-produced ozonized olive oil against common bacteria (Staphylococcus aureus, Escherichia coli, Klebisella pneumoniae, and Pseudomonas aeruginosa) and fungi (Candida albicans, Malassezia globosa, Aspergillus niger, Aspergillus fumigatus and Trichophyton mentagrophytes) were evaluated. Both microdilution and diffusion in agar methods were used to assess antimicrobial activity. The minimal concentrations of ozonized olive oil that inhibited all tested bacteria and fungi were 0.8% and 3.12%, respectively. Cytotoxicity studies using murine fibroblasts indicate that ozonized olive oil has a low cytopathic effect up to a concentration of 6.25%. Ozonized vegetable oils have good antimicrobial efficacy and low cytotoxicity. However, it is necessary to develop a standard methodology for interlaboratory comparison of results.

Słowa kluczowe

PL

aktywność antygrzybiczna; aktywność antymikrobowa; cytotoksyczność; MIC; ozonowany olej z oliwek

EN

antifungal; antimicrobial; cytotoxicity; MIC; ozonized olive oil

• Wydawca: Polskie Towarzystwo Ceramiczne
• Czasopismo: Materiały Ceramiczne
• Rocznik: 2018
• Tom: T. 70, nr 4
• Strony: 356--370
• Opis fizyczny: Bibliogr. 31 poz., rys., tab.

Twórcy

autor

Nocuń M.

• AGH University of Science and Technology, Faculty of Materials Science and Ceramics, al. Mickiewicza 30, 30-059 Kraków, Poland

autor

Krzyściak P.

• Jagiellonian University, Medical College, Department of Mycology, Czysta 18, 31-121 Krakow, Poland

autor

Niedźwiedzka E.

• Jagiellonian University, Medical College, Department of Mycology, Czysta 18, 31-121 Krakow, Poland

autor

Niedźwiedzki J.

• AGH University of Science and Technology, Faculty of Mechanical Engineering and Robotics, al. Mickiewicza 30, 30-059 Kraków, Poland

autor

Krzyściak-Kosińska R.

• Jagiellonian University, Medical College, Faculty of Pharmacy, Department of Medical Diagnostics, Medyczna 9, 30-688 Kraków, Poland

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