Aktywność biologiczna i metody syntezy sulfonamidów (przegląd literaturowy)

• Autorzy: Kołaczek A. , Fusiarz I , Ławecka J , Branowska D.

Warianty tytułu

EN

Biological activity and synthesis of sulfonamide derivatives: a brief review

• Języki publikacji: PL EN

Abstrakty

PL

Sulfonamidy (SO2-NH-) są lekami powszechnie stosowanymi ze względu na ich trwałość i tolerancję przez organizm człowieka. Stanowią dobrą grupę zabezpieczającą amin czyniąc je związkami aktywnymi biologicznie. Aktywność ta jest wynikiem obecności różnych grup funkcyjnych. Szerokie zastosowanie sulfonamidów stało się przyczyną poszukiwania nowych metod ich syntezy. Artykuł przedstawia krótki przegląd literaturowy najbardziej popularnych i nowoczesnych metod syntezy pochodnych sulfonamidowych.

EN

Sulfonamides (SO2-NH-) have been the center of the drug structures as they are quite stable and well tolerated in human beings. The sulfonamides are very important protected intermediates of amines with several types of biological activities. Activity of the sulfonamides is due to different functional groups present in them. Due to the broad applicability of sulfonamides, it is desirable to find general and effective methods for their synthesis. Different methods have been adopted to synthesize sulfonamides. Here is a short review which provides several of the most common and recent methods of sulfonamide synthesis.

Słowa kluczowe

PL

sulfonamidy; aktywność biologiczna; synteza sulfonamidów

EN

sulfonamide; biological activity; synthesis of sulfonamides

• Wydawca: Stowarzyszenie Inżynierów i Techników Przemysłu Chemicznego, ZW CHEMPRESS-SITPChem
• Czasopismo: Chemik
• Rocznik: 2014
• Tom: Vol. 68, nr 7
• Strony: 620--628
• Opis fizyczny: Bibliogr. 46 poz., rys.

Twórcy

autor

Kołaczek A.

• Instytut Chemii, Uniwersytet Przyrodniczo-Humanistyczny w Siedlcach

autor

Fusiarz I

• Instytut Chemii, Uniwersytet Przyrodniczo-Humanistyczny w Siedlcach

autor

Ławecka J

• Instytut Chemii, Uniwersytet Przyrodniczo-Humanistyczny w Siedlcach

autor

Branowska D.

• Instytut Chemii, Uniwersytet Przyrodniczo-Humanistyczny w Siedlcach

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