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Warianty tytułu
Aloe vera – selected biological properties
Języki publikacji
Abstrakty
Aloes jako ludowy medykament o wszechstronnych właściwościach prozdrowotnych jest znany ludzkości od setek lat. Ekstrakty aloesowe cieszą się ogromnym zainteresowaniem farmakologów, medyków oraz kosmetologów. Wykazano, że poszczególne składniki żelu aloesowego są antyoksydantami, stymulantami aktywności układu immunologicznego, mają właściwości antynowotworowe, obniżające poziom cukru i lipidów we krwi, a także wpływają pozytywnie na gojenie się ran czy oparzeń i działają przeciwzapalnie. Ostatnio opublikowano kilka znaczących prac, w których wykazano silne właściwości antyrakowe wybranych składników aloesu. Stąd, amerykańska FDA (ang. Food and Drug Administration) poparła projekty badań naukowych dotyczących zastosowania A. vera w leczeniu raka i AIDS u ludzi. W prezentowanej pracy przedstawiono ogólny skład żelu aloesowego wraz z najbardziej aktywnymi biologicznie substancjami. Scharakteryzowano aktywność antyoksydacyjną i przeciwdrobnoustrojową Aloesu, potencjalne działanie antynowotworowe oraz przedstawiono wpływ żelu aloesowego na przewód pokarmowy człowieka, przemiany węglowodanów, układ immunologiczny i proces gojenia się ran.
Aloe as a folk medicine with comprehensive healthpromoting properties has been known to humanity for hundreds of years. Aloe extracts are very popular among pharmacologists, medics and cosmetologists. It was demonstrated that the individual components of the aloe gel are antioxidants, stimulants of the immune system, have anti-cancer properties, lower blood sugar and lipid levels, and have a positive effect on wound healing, burns and anti-inflammatory effects. Recently, several significant papers have been published in which strong anti-cancer properties of selected aloe components have been demonstrated. Hence, the American Food and Drug Administration (FDA) has endorsed scientific research on the use of A. vera in the treatment of cancer and AIDS in humans. In the presented review, the general properties of Aloe are discussed, biological activity and the potential anti-cancer activity of the main, most active components of this plant are presented.
Czasopismo
Rocznik
Tom
Strony
191--195
Opis fizyczny
Bibliogr. 37 poz., tab.
Twórcy
autor
- Wydział Budownictwa i Inżynierii Środowiska, Politechnika Białostocka, ul. Wiejska 45A, 15-351 Białystok
autor
- Wydział Budownictwa i Inżynierii Środowiska, Politechnika Białostocka, ul. Wiejska 45A, 15-351 Białystok
autor
- Wydział Budownictwa i Inżynierii Środowiska, Politechnika Białostocka, ul. Wiejska 45A, 15-351 Białystok
Bibliografia
- Athiban P.P., Borthakur B.J., Ganesan S., Swathika B. (2012). Evaluation of antimicrobial efficacy of Aloe vera and its effectiveness in decontaminating guttapercha cones. Journal of Conservative Dentistry, Vol. 15, No. 3, 246-248.
- Attah M.O., Ishaya H.B., Chiroma M.S., Amaza D.S., Balogun S.U., Jacks T.W. (2015). Effect of Tamarindus indica (Linn) on the rate of wound healing in adult rabbits. IOSR Journal of Dental and Medical Sciences, Vol. 14, Issue 8, 80-84.
- Badakhsh M., Bahador, R.S., Afrazandeh S.S., Arefi F. (2016). A natural medicine and its effects: A revive article. International Journal of Pharmacy and Technology, Vol. 8, No. 3, 4790-4800.
- Boudreau M.D., Mellick P.W., Olson G.R., Felton R.P., Thorn B.T., Beland F.A. (2013). Clear evidence of carcinogenic activity by a whole-leaf extract of Aloe barbadensis miller (aloe vera) in F344/N rats. Toxicological Sciences, Vol. 131, Issue 1, 26-39.
- Chandan B.K., Saxena A.K., Shukla S., Sharma N., Gupta D.K., Suri K.A., Suri J., Bhadauria M., Singh B. (2007). Hepatoprotective potential of Aloe barbadensis Mill. against carbon tetrachloride induced hepatotoxicity. Journal of Ethnopharmacology, Vol. 111, Issue 3, 560-566.
- Chen H.C., Hsieh W.T., Chang W.C., Chung J.G. (2004). Aloeemodin induced In vitro G2/M arrest of cell cycle in human promyelocytic leukemia HL-60 cells. Food and Chemical Toxicology, Vol. 42, Issue 8, 1251-1257.
- Cieślik E., Turcza K. (2015). Właściwości prozdrowotne aloesu zwyczajnego Aloe vera (L.) Webb. (Aloe barbadensis Mill.). Postępy Fitoterapii, Vol. 2, 117-124.
- Cui Y., Ye Q., Wang H., Li Y., Yao W., Qian H. (2013). Hepatoprotective potential of Aloe vera polysaccharides against chronic alcohol-induced hepatotoxicity in mice. Journal of the Science of Food and Agriculture, Vol. 94, 1764-1771.
- El-Shemy HA, Aboul-Soud MA, Nassr-Allah AA, Aboul-Enein KM, Kabash A, Yagi A. (2010). Antitumor properties and modulation of antioxidant enzymes’ activity by Aloe vera leaf active principles isolated via supercritical carbon dioxide extraction. Current Medicinal Chemistry, Vol. 17, No. 2, 129-138.
- Fani M., Kohanteb J. (2012). Inhibitory activity of Aloe vera gel on some clinically isolated cariogenic and periodontopathic bacteria. Journal of Oral Science, Vol. 54, 15-21.
- Huang P.H., Huang C.Y., Chen M.C., Lee Y.T., Yue C.H., Wang H.Y., Lin H. (2013). Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER α Inhibition. Evidence-Based Complementary and Alternative Medicine, Vol. 37, 6123-6138.
- Irshad S., Butt M., Younus H. (2011). In-Vitro antibacterial activity of Aloe Barbadensis Miller (Aloe Vera). International Research Journal of Pharmaceuticals, Vol. 1, Issue 2, 59-64.
- Kathuria N., Gupta N., Manisha R., Prasad, Nikita (2010). Biologic effects of Aloe Vera gel. The Internet Journal of Microbiology, Vol. 9, No. 2, 1-6.
- Kumar S., Yadav J.P. (2014). Ethnobotanical and pharmacological properties of Aloe vera: A review. Journal of Medicinal Plant Research, Vol. 8, 1387-1398.
- Kuo P.L., Lin T.C., Lin C.C. (2002).The antiproliferative activity of aloe-emodin is through p53-dependent and p21- dependent apoptotic pathway in human hepatoma cell lines. Life Sciences, Vol. 71, Issue 16, 1879-1892.
- Lee H.Z., Hsu S.L., Liu M.C., Wu C.H. (2001). Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma. European Journal of Pharmacology, Vol. 431, Issue 3, 287-295.
- Lin K.Y., Uen Y.H. (2010). Aloe-emodin, an anthraquinone, In vitro inhibits proliferation and induces apoptosis in human colon carcinoma cells. Oncology Letters, Vol. 1, 541-547.
- Lissoni P., Rovelli F., Brivio F., Zago R., Colciago M., Messina G., Mora A., Porro G. (2009). A randomized study of chemotherapy versus biochemotherapy with chemotherapy plus Aloe arborescens in patients with metastatic cancer. In Vivo, Vol. 23, No. 1, 171-175.
- Liu P., Chen D., Shi J. (2013). Chemical Constituents, Biological Activity and Agricultural Cultivation of Aloe vera. Asian Journal of Chemistry, Vol. 25, 6477-6485.
- López A., de Tangil M.S., Vega-Orellana O., Ramírez A.S., Rico M. (2013). Phenolic constituents, antioxidant and preliminary antimycoplasmic activities of leaf skin and flowers of Aloe vera (L.) Burm. f. (syn. A. barbadensis Mill.) from the Canary Islands (Spain). Molecules, Vol. 18, No. 5, 4942-4954.
- Manvitha K., Bidya B. (2014). Aloe vera: a wonder plant its history, cultivation and medicinal uses. Journal of Pharmacognosy and Phytochemistry, Vol. 2, No. 5, 85-88.
- Nayak V., Gincy T.B., Prakash M., Joshi C., Rao S.S., Somayaji S.N., Madhav NV., Bairy K.L. (2011). Hepatoprotective activity of Aloe vera gel against paracetamol induced hepatotoxicity in albino rats. Asian Journal of Pharmaceutical and Biological Research, Vol. 1, 94-98.
- Nejatzadeh-Barandozi F. (2013). Antibacterial activities and antioxidant capacity of Aloe vera. Organic and Medicinal Chemistry Letters, Vol. 3, 5-21.
- Ndhlala A.R., Amoo S.O., Stafford G.I., Finnie J.F., Van Staden J. (2009). Antimicrobial, anti-inflammatory and mutagenic investigation of the South African tree aloe (Aloe barberae). Journal of Ethnopharmacology, Vol. 124, Issue 3, 404-408.
- Pandey R., Mishra A. (2010). Antibacterial activities of crude extract of Aloe barbadensis to clinically isolated bacterial pathogens. Applied Biochemistry and Biotechnology, Vol. 160, 1356-1361.
- Pecere T., Gazzola M. V., Mucignat C., Parolin C., Vecchia F.D., Cavaggioni A., Basso G., Diaspro A., Salvato B., Carli M., Palù G. (2000). Aloe-emodin is a new type of anticancer agent with selective activity against neuroectodermal tumors. Cancer Research, Vol. 60, 2800-2804.
- Philip J., John S., Iyer P. (2012). Antimicrobial activity of aloe vera barbedensis, daucus carota, emblica officinalis, honey and punica granatum and formulation of a health drink and salad. Malaysian Journal of Microbiology, Vol. 8, Issue 3, 141-147.
- Radha M.H., Laxmipriya N.P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine, Vol 5, Issue 1, 21-26.
- Rahmani A.H., Aldebasi Y.H., Srikar S., Khan A.A., Aly S.M. (2015). Aloe vera: Potential candidate in health management via modulation of biological activities. Pharmacognosy Review, Vol. 9, Issue 18, 120-126.
- Raksha B., Pooja S., Babu S. (2014). Bioactive compounds and medicinal properties of Aloe vera L.: An update. Journal of Plant Sciences, Vol. 2, No. 3, 102-107.
- Sahu P.K., Giri D.D., Singh R., Pandey P., Gupta S., Shrivastava A.K., Kumar A., Pandey K.D. (2013). Therapeutic and Medicinal Uses of Aloe vera: A Review. Pharmacology& Pharmacy, Vol. 4, 599-610.
- Saini M., Goyal P.K., Chaudhary G. (2010). Anti-tumor activity of Aloe vera against DMBA/croton oil-induced skin papillomagenesis in Swiss albino mice. Journal of Environmental Pathology, Toxicology and Oncology, Vol. 29, Issue 2, 127-135.
- Sanchez-Machado D.I., Lopes-Cervantes J., Sendon R. (2017). Aloe vera: Ancient knowledge with new frontiers. Trends in Food Science& Technology, Vol. 61, 94-102.
- Selva S. (2011). Antitumor activity of aloe vera against ehrlich ascitis carcinoma (eac) in swiss albino mice. International Journal of Pharma and Bio Sciences, Vol. 2, 400-409.
- Singh S., Sharma P.K., Kumar N., Dudhe R. (2010). Biological activities of Aloe vera. International Journal of Pharmacy and Technology, Vol. 2, No. 3, 259-280.
- Suboj P., Babykutty S., Srinivas P., Gopala S. (2012). Aloe Emodin Induces G2/M cell cycle arrest and apoptosis via activation of caspase-6 in human colon cancer cells. Pharmacology, Vol. 89, 91-98.
- Zamiara K. (2010). Aloes – jego tajemnicza moc. Farmacja Polska, Vol. 66, No. 7, 495-497.
Typ dokumentu
Bibliografia
Identyfikator YADDA
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