Preliminary evaluation of selected biologic properties of TiO2 and SiO2 layers on metallic substrates

• Autorzy: Urbański W. , Dragan S. , Gębarowska E. , Dzięgiel P. , Krzak-Roś J. , Miller M. , Pezowicz C. , Będziński R.
• Języki publikacji: EN

Abstrakty

EN

Despite of applying modern biomaterials during constructing long term orthopaedic implants, in clinical practice there are still present wide range of complications, particularly concerning matter of implant - tissue interactions. Since interaction between implant and living tissue depends mainly on biomaterial surface features, we decided to modify orthopaedic alloys to improve their biological properties. The object of this experiment was in vitro evaluation of selected biological properties, particularly cytotoxicity of titanium alloy and 316L stainless steel substrates coated with SiO2 or TiO2 thin films. The coatings were synthesized by sol-gel method. Each samples was placed into mouse fibroblast culture. The cultures in presence of tested materials were maintained for three days. We found no distinct toxic effect of tested biomaterials. We noticed increase of fibroblast proliferation in cultures with uncoated titanium and particularly SiO2 coated titanium plates.

Słowa kluczowe

EN

sol-gel coating; fibroblast; cytotoxicity; orthopaedic implant

• Wydawca: Polish Society for Biomaterials in Cracow
• Czasopismo: Engineering of Biomaterials
• Rocznik: 2010
• Tom: Vol. 13, no. 96-98
• Strony: 129--133
• Opis fizyczny: Bibliogr. 30 poz., tab., wykr., zdj.

Twórcy

autor

Urbański W.

• Departament of Orthopaedic Surgery and Traumatology, Wroclaw Medical University 213 Borowska Str., 50-556 Wroclaw, Poland

autor

Dragan S.

• Departament of Orthopaedic Surgery and Traumatology, Wroclaw Medical University 213 Borowska Str., 50-556 Wroclaw, Poland

autor

Gębarowska E.

• Department of Histology and Embryology Wroclaw Medical University 6a T.Chalubinskiego Str., 50-368 Wroclaw, Poland

autor

Dzięgiel P.

• Department of Histology and Embryology Wroclaw Medical University 6a T.Chalubinskiego Str., 50-368 Wroclaw, Poland

autor

Krzak-Roś J.

• Institute of Materials Science and Applied Mechanics, Wroclaw University of Technology 25 Smoluchowskiego Str., 50-370 Wroclaw, Poland

autor

Miller M.

• Department of Chemistry, Wroclaw University of Technology 4/6 Norwida Str., 50-373 Wroclaw, Poland
• Wroclaw Research Center EIT+ 147/149 Stablowicka Str., 54-066 Wroclaw, Poland

autor

Pezowicz C.

• Division of Biomedical Engineering and Experimental Mechanics, Wroclaw University of Technology 7/9 Lukasiewicza Str., 50-371 Wroclaw, Poland

autor

Będziński R.

• Division of Biomedical Engineering and Experimental Mechanics, Wroclaw University of Technology 7/9 Lukasiewicza Str., 50-371 Wroclaw, Poland

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