HPLC-MS analysis of sennosides A and B in aqueous extracts of Sennae folium prepared by a new microwave extraction method

• Autorzy: Dávid Á. Z , Mincsovics E. , Pápai K , Ludányi K , Antal I , Klebovich I
• Języki publikacji: EN

Abstrakty

EN

A new, simplified open-vessel microwave extraction (OVME) method with solid-phase extraction (SPE) for sample clean-up has been developed for specific investigation of sennosides A and B. Aqueous extracts of senna leaves ( Senna folium ) were prepared by different methods, including classic pharmacopoeial methods: concoction, infusion, and ultrasound extractions. The different extraction methods were compared by analysis of the sennosides A and B in the samples with a modified enantiomer-selective reversed-phase high-performance liquid chromatographic-tandem mass spectrometric method. HPLC was performed with a 4.6 mm × 150 mm, 3.5-µm particle C 8 column and simple gradient elution. The benefit of open-vessel microwave extraction is discussed.

Słowa kluczowe

EN

column liquid chromatography-tandem mass spectrometry (HPLC-MS); senna; sennosides A and B; microwave extraction; solid-phase extraction (SPE)

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2009
• Tom: Vol. 21, no. 3
• Strony: 473--482
• Opis fizyczny: Bibliogr. 18 poz., rys., tab.

Twórcy

autor

Dávid Á. Z

• Semmelweis University Department of Pharmaceutics Hőgyes Endre Street 7 1092 Budapest Hungary

autor

Mincsovics E.

• OPLC-NIT Ltd Andor Street 60 1119 Budapest Hungary
• Corvinus University Faculty of Horticultural Sciences, Department of Genetics and Plant Breading Budapest Hungary

autor

Pápai K

• Semmelweis University Department of Pharmaceutics Hőgyes Endre Street 7 1092 Budapest Hungary

autor

Ludányi K

• Semmelweis University Department of Pharmaceutics Hőgyes Endre Street 7 1092 Budapest Hungary

autor

Antal I

• Semmelweis University Department of Pharmaceutics Hőgyes Endre Street 7 1092 Budapest Hungary
• Semmelweis University Department of Pharmaceutics Hőgyes Endre Street 7 1092 Budapest Hungary

autor

Klebovich I

• Semmelweis University Department of Pharmaceutics Hőgyes Endre Street 7 1092 Budapest Hungary

Bibliografia

• [1] S. Başgel and S.B. Erdemoğlu, Sci. Total. Environ., 359 , 82–89 (2006)
• [2] E. Ernst, Am. J. Med., 104 , 171–178 (1998)
• [3] European Medicines Agency: Community Herbal Monograph on Cassia Senna L. and Cassia Angustifolia Vahl, Folium. London, 26 October 2006. http://www.emea.europa.eu/pdfs/human/hmpc/sennae_folium/5186906en.pdf
• [4] V. Lopez-Avila, Crit. Rev. Anal. Chem., 29 , 195–230 (1999)
• [5] V. Camel, Trends Anal. Chem., 19 , 229–248 (2000)
• [6] M. Letellier, H. Budzinski, L. Charrier, and S. Wise, Spectroscopy, 13 , 71–80 (1996)
• [7] M. Letellier and H. Budzinski, Analysis, 27 , 259–271 (1999)
• [8] Á.Z. Dávid, G. Rajkai, K. Ludányi, M. Lengyel, I. Antal, and I. Klebovich, Evaluation of Microwave-Assisted Extraction for the Preparation of Medical Teas, 5th World Meeting on Pharmaceutics, Biopharmaceutics, and Pharmaceutical Technology, Geneva, March 27–30, 2006; poster #87, program book p. 64
• [9] C.S. Eskilsson and E. Björklund, J. Chromatogr. A, 902 , 227–250 (2000)
• [10] J. Koyama, I. Morita, and N. Kobayashi, J. Chromatogr. A, 1145 , 183–189 (2007)
• [11] Y. Min, H. Jian, C. Hubiao, Z. Junhua, and G. Dean, J. Am. Soc. Mass. Spectrom., 18 , 82–91 (2007)
• [12] M.R.S. Fuh and H.J. Lin, Tamkang J. Sci. Eng., 6 , 31–36 (2003)
• [13] A. Arshi, M.Z. Abdin, and M. Iqbal, Sci. Hortic. — Amsterdam, 111 , 84–90 (2006)
• [14] C. Terreaux, Q. Wang, J.R. Ioset, K. Ndjoko, W. Grimminger, and K. Hostettmann, Planta Med., 68 , 349–354 (2002)
• [15] T. Padumanonda and W. Gritsanapan, Southeast Asian J. Trop. Med. Public Health, 37 , 388–393 (2006)
• [16] J. Koyama, I. Morita, and N. Kobayashi, J. Chromatogr. A, 1145 , 183–189 (2007)
• [17] S.W. Sun and H.T. Su, J. Pharm. Biomed. Anal., 29 , 881–894 (2002)
• [18] S. Zhao, K.C. Kwok, and H. Liang, Sep. Purif. Technol., 55 , 307–312 (2007)