Exploring PET imaging with scattered photons and polarization characteristics

• Autorzy: Das Pragya , Verma Ritesh , Prasad Kaustav

Identyfikatory

DOI

10.5604/01.3001.0054.8576

• Języki publikacji: EN

Abstrakty

EN

Objective: To demonstrate the potential of PET imaging using scattered photons, we have proposed a novel technique that utilizes single-tissue-scattered events based solely on time-of-flight (TOF) information, without relying on energy data. Additionally, we explored the possibility of improving image quality by applying polarization selection criteria for true events. Methods: Due to Compton scattering within the phantom, scattered photons exhibit reduced energy, which remains unknown in our analysis. For a fixed scattering angle, the locus of the scattering point forms an arc of a circle in two dimensions (2D). With known TOF, we can trace the locus of the annihilation point for all possible scattering angles and positions. Our procedure involves identifying the annihilation-point loci corresponding to all pairs of single-scattered photons and merging them. In a separate study, we utilized the classical concept of orthogonal polarization of two annihilation photons, combined with energy filtering, to select genuine (true) events. Results: Our proof-of-concept study successfully demonstrated that the TOF-based approach could yield an image of a point source. The merging of annihilationpoint loci from numerous pairs of single-scattered photons produced a localized region for the source activity. The intensity profile showed a finite width of 14 mm for 1 ps uncertainty in TOF. Additionally, another analysis utilizing polarization and energy criteria generated a clean dataset for true events, with minimal background interference (containing random coincidences) at a high event rate. Conclusions: The simulation-based study validated our proposed model, indicating its potential to enhance the sensitivity and accuracy of event selection in PET imaging. These findings lay a solid foundation for further research into advanced PET imaging techniques that incorporate single-scattered events.

Słowa kluczowe

EN

positron emission tomography; compton scattering; time of flight; polarization

• Wydawca: Uniwersytet Jagielloński - Collegium Medicum ; Index Copernicus Sp. z o.o.
• Czasopismo: Bio-Algorithms and Med-Systems
• Rocznik: 2024
• Tom: Vol. 20, Special issue
• Strony: 10--16
• Opis fizyczny: Bibliogr. 21 poz., rys., tab.

Twórcy

autor

Das Pragya

• Indian Institute of Technology Bombay, India

• https://orcid.org/0000-0002-0764-4058

autor

Verma Ritesh

• Indian Institute of Technology Bombay, India

• https://orcid.org/0009-0009-9745-3981

autor

Prasad Kaustav

• Indian Institute of Technology Bombay, India

Bibliografia

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