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Tytuł artykułu

Antimicrobial Screening of Synthesized some Novel Azomethines via Organic Base

Wybrane pełne teksty z tego czasopisma
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The author has synthesized azomethines in which carbonyl group is replaced by amine of acid hydrazides. The intermediates were prepared by using 2-mercapto benzimidazole with N-(4-Acetyl-phenyl)-2-chloro-acetamide in the presence of K2CO3. The Resulted product was further treated with different substituted of acid hydrazide in ethanol to yield the titled compounds using a catalytic amount of acetic acid. New products were examined for their antibacterial effects against Gram-positive and Gram-negative strains and antifungal were highly potent with lowest MIC Values. The structural assignments of the new products were done on the basis of FT-IR, NMR, Mass spectroscopy and elemental analysis.
Rocznik
Tom
Strony
25--33
Opis fizyczny
Bibliogr. 15 poz., tab., wz.
Twórcy
autor
  • Department of Chemistry, Sheth M. N. Science College, NGES Campus, Patan - 384265, India
autor
  • Department of Chemistry, Sheth M. N. Science College, NGES Campus, Patan - 384265, India
autor
  • Department of Chemistry, Sheth M. N. Science College, NGES Campus, Patan - 384265, India
Bibliografia
  • [1] Camacho J., Barazarte A., Gamboa N., Rodrigues J., Rojas R., Vaisberg A., Gilman R.,Charris J., Bioorg. & Med. Chem. 19 (2011) 2023-2029.
  • [2] Porcari A.R., Devivar R.V., Kucera L.S., Drach J.C., Townsend L.B., J Med Chem 41(1998) 1252-1262.
  • [3] Victor F., Brown T.J., Campanale K., Heinz B.A., Shirpley L.A., Su S.K., Tang J.,Vance L.M., Spitzer W., J Med Chem 40 (1997) 1511-1518.
  • [4] Ansari K.F., Lal C., Eur. J. Med. Chem. 44 (2009) 4028-4033.
  • [5] Hosamani K.S., Shingalapur R.V., Rangappa S., Hugar M.H., Eur J Med Chem 45(2010) 1753-1759.
  • [6] Patil A., Ganguly S., Surana S., Rasayan J Chem. 1 (2008) 447-460.
  • [7] Deep Joshi, Kalpesh Parikh, Med. Chem. Res. 22 (2012) 3688-3697.
  • [8] Kalpesh S. Parikh and Sandip P. Vyas, Archives of Applied Science Res. 4 (2012) 1578-1580.
  • [9] Grocer, H., Kus, C., Boykin, D.W., Yildiz, S., Altanlar, N. Synthesis and Anti-fungal Properties of Some Benzimidazole Derivatives. Bioorg. Med. Chem.10 (2002) 2589-2596.
  • [10] Nicholson R.M., Murphy J.R., Dearden J.R., Journal of Pharmacy and Pharmacology 34 (1982) 106-111.
  • [11] Fang B., Zhou C.H., Rao X.C., Eur. J. Med. Chem. 45 (2010) 4388-4398.
  • [12] E. F. Magomedova, V. V. Pinyaskin, A. Sh. Aminova, Pharma. Chem. J. 41 (2007) 474-475.
  • [13] Yadav S., Kumar P., Clercq E.D., Balzarini J., Pannecouque C., Dewan S.K.,Narasimhan B., Eur. J. Med. Chem. 45 (2010) 5985-5997.
  • [14] John Maria Xavier, M. Arockia Raj, J. Margaret Marie, Journal of Chemical and Pharmaceutical Research 4 (2012) 669-672.
  • [15] P.C. Hannan, Vet. Res. 31 (2000) 373-395.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-35bf30af-fb42-46ef-8593-86b59623c17e
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