Optimization of the WLS design for positron emission mammography and Total-Body J-PET systems

• Autorzy: Georgadze Anzori , Shivani Shivani , Ardebili Keyvan Tayefi , Moskal Paweł

Identyfikatory

DOI

10.5604/01.3001.0054.1942

• Języki publikacji: EN

Abstrakty

EN

Total-body positron emission tomography (PET) instruments are medical imaging devices that detect and visualize metabolic activity in the entire body. The PET scanner has a ring-shaped detector that surrounds the patient and detects the gamma rays emitted by the tracer as it decays. Usually these detectors are made up of scintillation crystals coupled to photodetectors that convert the light produced by the scintillation crystal into electrical signals. Jagiellonian Positron Emission Mammograph (J-PEM) is the first J-PET prototype module based on a novel idea with a plastic scintillator and wavelength shifter (WLS). At the same time, it is a prototype module for the Total-Body J-PET system. J-PEM can be an effective system for the detection and diagnosis of breast cancer in its early stage by improving sensitivity. This can be achieved using the superior timing properties of plastic scintillators combined with the WLS sheets readout. In this paper we present an application of the Geant4 program for simulating optical photon transport in the J-PEM module. We aim to study light transport within scintillator bars and WLS sheets to optimize gamma-ray hit position resolution. We simulated a pencil beam of 511 keV photons impinging the scintillator bar at different locations. For each condition we calculated the value of the pulse height centroid and the spread of the photon distribution. Some free parameters of the simulation, like reflectivity and the effective attenuation length in the sheet, were determined from a comparison to experimental data. Finally, we estimated the influence of the application of WLS layer in the Total-Body J-PET on the scatter fraction. To optimize the performance of the J-PEM module we compared geometry WLS strips 50 and 83. It was found that spatial resolution was 2.7 mm and 3.5 mm FWHM for 50 and 83 WLS strips, respectively. Despite the better granularity, the 83-strip WLS geometry exhibited poorer resolution due to fewer photons being transmitted to the strip, resulting in large fluctuations of signal.

Słowa kluczowe

EN

J-PET; total-body PET; medical imaging; J-PEM

• Wydawca: Uniwersytet Jagielloński - Collegium Medicum ; Index Copernicus Sp. z o.o.
• Czasopismo: Bio-Algorithms and Med-Systems
• Rocznik: 2023
• Tom: Vol. 19, no. 1
• Strony: 114--123
• Opis fizyczny: Bibliogr. 39 poz., rys., tab.

Twórcy

autor

Georgadze Anzori

• Institute for Nuclear Research of the NAS of Ukraine, Kyiv, Ukraine
• Institute of Physics, University of Tartu, Tartu, Estonia

• https://orcid.org/0000-0003-3512-1497

autor

Shivani Shivani

• Faculty of Physics, Astronomy, and Applied Computer Science, Jagiellonian University, Krakow, Poland

autor

Ardebili Keyvan Tayefi

• Doctoral School of Exact and Natural Science, Jagiellonian University, Krakow, Poland
• Faculty of Physics, Astronomy, and Applied Computer Science, Jagiellonian University, Krakow, Poland
• Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, Krakow, Poland
• Center for Theranostics, Jagiellonian University, Krakow, Poland

• https://orcid.org/0000-0001-8764-1588

autor

Moskal Paweł

• Faculty of Physics, Astronomy, and Applied Computer Science, Jagiellonian University, Krakow, Poland
• Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, Krakow, Poland
• Center for Theranostics, Jagiellonian University, Krakow, Poland

• https://orcid.org/0000-0002-4229-3548

Bibliografia

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Uwagi

Opracowanie rekordu ze środków MEiN, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2022-2023).