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PVA hydrogel deformation in response to change in temperature or pH

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Języki publikacji
EN
Abstrakty
EN
Biocompatibility, biodegradability and non-toxicity are the main attributes of any material to be used in biomedical applications. Among all the potential stimuli, pH, salt and temperature exist naturally in the internal environment of the human body. Hence internal stimuli responsive hydrogels can be exploited for specific drug delivery and tissue replacement. Poly(vinyl alcohol) (PVA) is the world’s largest volume synthetic polymer, produced for its excellent chemical resistance, physical properties and complete biodegradability, which has resulted in broad practical applications. PVA could be considered a suitable host material due to its good thermo-stability, chemical resistance and film-forming ability. It is also an important material because of its large-scale applications. Novel data analysis techniques were developed to analyze the response of PVA to external stimuli, including temperature and/or pH. The presented non-contact method shows that the PVA polymer gel, physically cross-linked by freezing and thawing, shrinks and swells under the influence of temperature, which is a reversible phenomenon. Under the given conditions, such as temperature, pH and mechanical load, the dominant factor affecting the swelling or contraction of the hydrogel is the change in the temperature of the liquid in which the PVA hydrogel sample is immersed.
Rocznik
Strony
art. no. e136724
Opis fizyczny
Bibliogr. 27 poz., rys., tab.
Twórcy
  • Department of Mechatronics, Bydgoszcz Kazimierz Wielki University, Kopernika 1 street, 85-074 Bydgoszcz, Poland
Bibliografia
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  • [9] Y. Masuda, T. Tanaka, and T. Nakanishi, “Ion-specific swelling behavior of poly(vinyl alcohol) gel prepared by γ-ray irradiation”, Colloid. Polym. Sci. 279, 1241–1244 (2001).
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  • [11] K. Kazimierska-Drobny and M. Kaczmarek, ”Effect of NaCl and KCl solutions on deformation of PVA hydrogel – chemo-mechanical coupling” (in English), Polimery 1 (44) (2020).
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  • [15] Y. Liu, L. Geever, J.E. Kennedy, C.L. Higginbotham, P.A. Cahill, and G.B. McGuinness, “Thermal behavior and mechanical properties of physically crosslinked PVA/Gelatin hydrogels”, J. Mech. Behav. Biomed. Mater. 3, 203‒209 (2010).
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  • [26] M. Rizwan, R. Yahya, Z. Hassan, and M. Azzahari, ”pH sensitive hydrogels in drug delivery: Brief history, properties, swelling, and release mechanism, material selection and applications”, Polymers 9, 137 (2017).
  • [27] M. Sabzi, M.J. Afshari, and M. Babaahmadi, “pH-dependent swelling and antibiotic release from citric acid crosslinked poly(vinyl) alcohol (PVA)/nano silver hydrogels”, Colloids Surf. B. 1888, 110757 (2020).
Uwagi
Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2021).
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-329c8459-774d-4222-99ae-af30fb08d5e6
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