Relationships between acoustical properties and stiffness of soft tissue phantoms

• Autorzy: Gambin B. , Kruglenko E. , Byra M.
• Języki publikacji: EN

Abstrakty

EN

Polyvinyl-alcohol cryogel is commonly used for soft tissue phantom manufacture. The gel formation from an aqueous solution of polyvinyl-alcohol takes place during the freezing and thawing cycle. The aim of this work was to assess the degree of gel solidification, hence the material stiffness, by means of quantitative ultrasound. We manufactured three phantoms which differed in the number of freezing/thawing cycles. First, tissue phantoms were examined with an elastography technique. Next, we measured the speed of sound and the attenuation coefficient. What is more, the inter structure variations in phantoms were assessed with the Nakagami imaging which quantifies the scattering properties of the backscattered ultrasound echo. Obtained results confirmed the connection between the number of freezing/thawing cycles and the solidification p rocess. We d efined th e bo undary layer as a region which has a different structure than the sample interior. Next, for each phantom this layer was extracted based on a Nakagami parameter map. We calculated that the thickness of the boundary layer was lower in samples which were subjected to a larger number of freezing/thawing cycles.

Słowa kluczowe

EN

soft tissue phantoms; elastography; ultrasound attenuation; speed of sound; Nakagami maps; stiffness

• Wydawca: Polskie Towarzystwo Akustyczne. Oddział Gdański
• Czasopismo: Hydroacoustics
• Rocznik: 2016
• Tom: Vol. 19
• Strony: 111--120
• Opis fizyczny: Bibliogr. 12 poz., rys., tab.

Twórcy

autor

Gambin B.

• Institute of Fundamental Technological Research, Polish Academy of Science, Pawińskiego 5B, 02-106 Warsaw, Poland

autor

Kruglenko E.

• Institute of Fundamental Technological Research, Polish Academy of Science, Pawińskiego 5B, 02-106 Warsaw, Poland

autor

Byra M.

• Institute of Fundamental Technological Research, Polish Academy of Science, Pawińskiego 5B, 02-106 Warsaw, Poland

Bibliografia

• [1] J.L. Valentın, D. Lopez, R. Hernandez, C. Mijangos, and K. Saalwachter, Structure of Poly(vinyl alcohol) Cryo-Hydrogels as Studied by Proton Low-Field NMR Spectroscopy, Macromolecules, Vol.42, 263-272, 2009.
• [2] K.J.M. Surry, H.J.B. Austin, A. Fenster and T.M. Peters, Poly(vinyl alcohol) cryogel phantoms for use in ultrasound and MR imaging, Physics in Medicine and Biology, Vol. 49, Number 24,5529-5546, 2004.
• [3] W. Xia, D. Piras, M. Heijblom, W. Steenbergen, T.G. van Leeuwen, Srirang Manohar, Poly(vinyl alcohol) gels as photoacoustic breast phantoms revisited, Journal of Biomedical Optics, Vol. 16, no.7, 075002, 2011. doi:10.1117/1.3597616.
• [4] B. Gambin, E. Kruglenko, Temperature Measurement by Statistical Parameters of Ultrasound Signal Backscattered from Tissue Samples, Acta Physica Polonica A, Vol. 128, 1-A, A-72 - A-78, 2015.
• [5] M. Byra, B. Gambin, Temperature detection based on nonparametric statistics of ultrasound echoes, Hydroacoustics, Vol. 18, 17-23, 2015.
• [6] E. Kruglenko, B. Gambin, RF signal amplitude statistics during temperature changes in tissue phantoms, Hydroacoustics, Vol. 17, 115-122, 2014.
• [7] J. Mamou, M.L. Oelze, Eds., Quantitative Ultrasound in Soft Tissues, Springer 2013.
• [8] Z. Trawiński, J. Wójcik, A. Nowicki, R. Olszewski, A. Balcerzak, E. Frankowska, A. Zegadło, P. Rydzyński, Strain examinations of the left ventricle phantom by ultrasound and multislices computed tomography imaging, Biocybernetics and Biomedical Engineering, Vol.35, 255-263, 2015.
• [9] H. Mehrabian, A. Samani, Constrained hyperelastic parameters reconstruction of PVA (Polyvinyl Alcohol) phantom undergoing large deformation, Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling, eds. M. I. Miga, K. H. Wong, Proc. of SPIE Vol. 7261, 72612G, 2009, doi: 10.1117/12.813871.
• [10] P.-H. Tsui, Y.-L. Wan, Y.-T. Chien, C.-C. Yeh, C.-Y. Wang, Dependency of Ultrasonic Nakagami Images on The Mechanical Properties of Scattering Medium, Journal of Medical and Biological Engineering, Vol.33, 1, 95-102, 2013.
• [11] M. Byra, A. Nowicki, H. Piotrzkowska-Wróblewska, J. Litniewski, K. Dobruch-Sobczak, Correcting the influence of tissue attenuation on Nakagami distribution shape parameter estimation, Ultrasonics Symposium (IUS), 2015 IEEE International, 1-4, 2015.
• [12] M. Byra, A. Nowicki, H. Piotrzkowska-Wróblewska, K. Dobruch-Sobczak, Classification of breast lesions using segmented quantitative ultrasound maps of homodyned K distribution parameters, Medical Physics, Vol. 43, 5561-5569, 2016.

Uwagi

PL

Opracowanie ze środków MNiSW w ramach umowy 812/P-DUN/2016 na działalność upowszechniającą naukę (zadania 2017)