Natryskiwane metodą APS powłoki hydroksyapatytowe do zastosowań w implantologii

• Autorzy: Dudek Agata

Identyfikatory

DOI

10.15199/40.2022.6.3

Warianty tytułu

EN

APS sprayed hydroxyapatite coatings for use in implantology

• Języki publikacji: PL

Abstrakty

PL

Ze względu na możliwe zastosowanie biodegradowalnych implantów ze stopów magnezu w ortopedii oraz w celu zwiększenia ich odporności na korozję można pokryć ich powierzchnię bioaktywnymi powłokami, np. hydroksyapatytowymi. W pracy zaproponowano wprowadzenie modyfikacji w zakresie natryskiwanych plazmowo metodą APS (atmosferic plasma spraying) powłok hydroksyapatytowych, polegającej na zastosowaniu dodatku 20% wag. ceramiki YSZ (yttria stabilized zirconia). Analizowano morfologię oraz mikrostrukturę powłok za pomocą mikroskopu cyfrowego KEYENCE VHX-7000, a także grubość – miernikiem Testan DT-20 AN 120 157 oraz skład fazowy – z użyciem dyfraktometru Seifert T-T. W celu potwierdzenia możliwości zastosowania powłok w implantologii przeprowadzono badania odporności korozyjnej w symulowanym płynie ustrojowym, odwzorowującym warunki ludzkiego organizmu.

EN

Taking into account the potential use in orthopedics and obtaining an increase in corrosion resistance of biodegradable implants made of magnesium alloys, bioactive coatings, e.g. hydroxyapatite, can be applied to their surface. In this paper, a modification of the APS (atmosferic plasma spraying) plasma spraying method was proposed for hydroxyapatite coatings by adding 20% wt. YSZ ceramics (yttria stabilized zirconia). The morphology and microstructure of the coatings were analysed using the KEYENCE VHX-7000 digital microscope, thickness using the Testan DT-20 AN 120 157 meter and phase composition using a Seifert T-T diffractometer. In order to confirm the possibility of using coatings in implantology, corrosion resistance tests were carried out in a simulated body fluid mapping the conditions of the human body.

Słowa kluczowe

PL

stop magnezu; natryskiwanie plazmowe; powłoka hydroksyapatytowa; ceramika cyrkonowa

EN

magnesium alloy; plasma spraying; hydroxyapatite coating; zirconium ceramics

• Wydawca: Wydawnictwo SIGMA-NOT
• Czasopismo: Ochrona przed Korozją
• Rocznik: 2022
• Tom: nr 6
• Strony: 182--185
• Opis fizyczny: Bibliogr. 28 poz., fot., tab., wykr.

Twórcy

autor

Dudek Agata

• Katedra Inżynierii Materiałowej, WIPiTM, Politechnika Częstochowska

• https://orcid.org/0000-0001-9115-028X

Bibliografia

• [1] Chen Q., Thouas G.A. 2015. “Metallic Implant Biomaterials”. Materials Science and Engineering: R: Reports 87: 1–57.
• [2] Zhang S., Zhang X., Zhao Ch., Li J., Song Y., Xie Ch., Tao H., Zhang Y., He Y., Jiang Y., Bian Y. 2010. “Research on an Mg–Zn Alloy as a Degradable Biomaterial”. Acta Biomaterialia 6 (2): 626–640.
• [3] Song M.-S., Zeng R.-Ch., Ding Y.-F., Li R.W., Easton M., Cole I., Birbilis N., Chen X.-B. 2019. “Recent Advances in Biodegradation Controls over Mg Alloys for Bone Fracture Management: A Review”. Journal of Materials Science and Technology 35 (4): 535–544.
• [4] Atrens A., Johnston S., Shi Z., Dargusch M.S. 2018. “Viewpoint – Understanding Mg Corrosion in the Body for Biodegradable Medical Implants”. Scripta Materialia 154: 92–100.
• [5] Hofstetter J., Martinelli E., Weinberg A.M., Becker M., Mingler B., Uggowitzer P.J., Löffler J.F. 2015. “Assessing the Degradation Performance of Ultrahigh-Purity Magnesium In Vitro and In Vivo”. Corrosion Science 91: 29–36.
• [6] Witte F., Fischer J., Nellesen J., Crostack H.-A., Kaese V., Pisch A., Beckmann F., Windhagen H. 2006. “In Vitro and In Vivo Corrosion Measurements of Magnesium Alloys”. Biomaterials 27 (7): 1013–1018.
• [7] Witte F., Hort N., Vogt C., Cohen S., Kainer K.U., Willumeit R., Feyerabend F. 2008. “Degradable Biomaterials Based on Magnesium Corrosion”. Current Opinion in Solid State and Materials Science 12 (5–6): 63–72.
• [8] Staiger M.P., Pietak A.M., Huadmai J., Dias G. 2006. “Magnesium and Its Alloys as Orthopedic Biomaterials: A Review”. Biomaterials 27 (9): 1728–1734.
• [9] Saris N.-E.L., Mervaala E., Karppanen H., Khawaja J.A., Lewenstam A. 2000. “Magnesium: An Update on Physiological, Clinical and Analytical Aspects”. Clinica Chimica Acta 294 (1–2): 1–26.
• [10] Uppal G., Thakur A., Chauhan A., Bala S. 2022. “Magnesium Based Implants for Functional Bone Tissue Regeneration – A Review”. Journal of Magnesium and Alloys 10 (2): 356–386.
• [11] Witte F. 2015. “Reprint of: The History of Biodegradable Magnesium Im- plants: A Review”. Acta Biomaterialia 23 (1): S28–S40.
• [12] Shadanbaz S., Dias G.J. 2012. “Calcium Phosphate Coatings on Magnesium Alloys for Biomedical Applications: A Review”. Acta Biomaterialia 8 (1): 20– –30.
• [13] Montazerian M., Hosseinzadeh F., Migneco C., Fook M.V.L., Baino F. 2022. “Bioceramic Coatings on Metallic Implants: An Overview”. Ceramics International 48 (7): 8987–9005.
• [14] Huang Y., Qu Y., Yang B., Li W., Zhang B., Zhang X. 2009. “In Vivo Biological Responses of Plasma Sprayed Hydroxyapatite Coatings with an Electric Polarized Treatment in Alkaline Solution”. Materials Science and Engineering: C 29 (8): 2411–2416.
• [15] Grubač Z., Metikoš-Huković M., Babić R. 2013. “Electrocrystallization, Growth and Characterization of Calcium Phosphate Ceramics on Magnesium Alloys”. Electrochimica Acta 109: 694–700.
• [16] Yin Z.-Z., Qi W.-Ch., Zeng R.-Ch., Chen X.-B., Gu Ch.-D., Guan S.-K., Zheng Y.-F. 2020. “Advances in Coatings on Biodegradable Magnesium Alloys”. Journal of Magnesium and Alloys 8 (1): 42–65.
• [17] Ji X.-J., Gao L., Liu J.-Ch., Wang J., Cheng Q., Li J.-P., Li S.-Q., Zhi K.-Q., Zeng R.-Ch., Wang Z.-L. 2019. “Corrosion Resistance and Antibacterial Properties of Hydroxyapatite Coating Induced by Gentamicin-Loaded Polymeric Multilayers on Magnesium Alloys”. Colloids and Surfaces B: Biointerfaces 179 (1): 429–436.
• [18] Sreekanth D., Rameshbabu N. 2012. “Development and Characterization of MgO/Hydroxyapatite Composite Coating on AZ31 Magnesium Alloy by Plasma Electrolytic Oxidation Coupled with Electrophoretic Deposition”. Materials Letters 68: 439–442.
• [19] Pan Y.K., Chen C.Z., Wang D.G., Lin Z.Q. 2013. “Preparation and Bioactivity of Micro-Arc Oxidized Calcium Phosphate Coatings”. Materials Chemistry and Physics 141 (2–3): 842–849.
• [20] Wang Q., Tan L., Xu W., Zhang B., Yang K. 2011. “Dynamic Behaviors of a Ca–P Coated AZ31B Magnesium Alloy during In Vitro and In Vivo Degradations”. Materials Science and Engineering: B 176 (20): 1718–1726.
• [21] Tomozawa M., Hiromoto S. 2011. “Growth Mechanism of Hydroxyapatite-Coatings Formed on Pure Magnesium and Corrosion Behavior of the Coated Magnesium”. Applied Surface Science 257 (19): 8253–8257.
• [22] Zhang A.-M., Lenin P., Zeng R.-Ch., Kannan M.B. 2022. “Advances in Hydroxyapatite Coatings on Biodegradable Magnesium and Its Alloys”. Journal of Magnesium and Alloys.
• [23] Zhang Z.-Q., Yang Y.-X., Li J.-A., Zeng R.-Ch., Guan S.-K. 2021. “Advances in Coatings on Magnesium Alloys for Cardiovascular Stents – A Review”. Bioactive Materials 6 (12): 4729–4757.
• [24] Rahman M., Li Y., Wen C. 2020. “HA Coating on Mg Alloys for Biomedical Applications: A Review”. Journal of Magnesium and Alloys 8 (3): 929–943.
• [25] Saji V.S. 2021. “Recent Progress in Superhydrophobic and Superamphiphobic Coatings for Magnesium and Its Alloys”. Journal of Magnesium and Alloys 9 (3): 748–778.
• [26] Dudek A., Morel. S. 2019. Sposób nanoszenia powłoki hydroksyapatytowej na implanty rozpuszczalne w ludzkich płynach ustrojowych. Patent PL 233162 B1 WUP 09/19.
• [27] Lewis G. 2017. “Nanostructured Hydroxyapatite Coating on Bioalloy Substrates: Current Status and Future Directions”. Journal of Advances in Nanomaterials 2 (1): 65–82.
• [28] Baslayici S., Bugdayci M., Acma M.E. 2021. “Corrosion Behaviour of Hydroxyapatite Coatings on AZ31 and AZ91 Magnesium Alloys by Plasma Spray”. Journal of Ceramic Processing Research 22 (1): 98–105.

Uwagi

Opracowanie rekordu ze środków MEiN, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2022-2023).