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Mimetics of manganese catalase as synthetic antioxidants
Języki publikacji
Abstrakty
The coordination chemistry of manganese complexes with heteroaromatic ligands have received considerable attention in modern inorganic chemistry due to its wide range of applications. One of them is related with its potential biological role associated with prevention of oxidative stress injuries. Manganese complexes are one of the most versatile and interesting synthetic systems that can act as artificial mimics of manganese-containing metalloenzymes such as manganese catalase (Mn-CAT). Due to the potential use as catalytic scavengers of H2O2, numerous and diverse, very structurally interesting Mn compounds exhibiting CAT-like activity have been reported so far. In this short review, the relevant features of both, structural, as well as, functional mimics of manganese catalase and their CAT-like activity are presented and some insights into the role of the bridging ligands, endogenous bases, and first- and second-sphere effects on the catalysis are discussed.
Wydawca
Czasopismo
Rocznik
Tom
Strony
319--341
Opis fizyczny
Bibliogr. 54 poz., rys., schem.
Twórcy
- Instytut Chemii Fizycznej Polskiej Akademii Nauk, ul. Kasprzaka 44/52, 01-224 Warszawa
autor
- Instytut Chemii, Uniwersytet Jana Kochanowskiego w Kielcach, ul. Uniwersytecka 7, 25-406 Kielce
autor
- Wydział Rehabilitacji, Wyższa Szkoła Rehabilitacji w Warszawie, ul. Marcina Kasprzaka 49, 01-234 Warszawa
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Uwagi
Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2021).
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-2d17ad67-5e09-4189-a9bd-1877a01f7816