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Polynomial modeling of retinal vessels for tortuosity measurement

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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Tortuosity is one of the micro vascular change that is observed in many retinopathies. Its early detection can prevent the progression of various retinopathies to a critical stage at which a person may become blind. Here, we propose a novel method for the measurement of tortuosity by polynomial modeling of retinal vessels for the analysis of hypertensive retinopathy. The proposed method is tested on a set of 30 arteries and 30 veins vessel images collected from the Retinal Vessel Tortuosity Dataset (RET-TORT). Also, 90 vessel segments from Digital Retinal Images for Vessel Extraction (DRIVE) and 149 vessel segments from High Resolution Fundus (HRF) databases are used for tortuosity evaluation. The experimental results demonstrate that the order of the polynomial increases with the increase in the tortuosity of the blood vessels. Hence, the order of the polynomial can be used as a parameter to classify vessels as non-tortuous and tortuous. The results of the method are also evaluated subjectively and the inter-rater agreement analysis is made by using Fleiss Kappa index. The Spearman's rank order correlation coefficient is used to analyze the correlation between the ranking provided by the expert in the RET-TORT database and the ranking obtained by the proposed method. The results demonstrate that this method is capable of evaluating the tortuosity and classify vessel segments into non-tortuous or tortuous effectively.
Twórcy
  • Department of Electronics and Communication Engineering (ECE), Gauhati University, Guwahati 781014, Assam, India
  • Department of Electronics and Communication Engineering (ECE), Gauhati University, Guwahati, Assam, India
Bibliografia
  • [1] Abdalla M, Hunter A, Al-Diri B. Quantifying retinal blood vessels tortuosity – review. Science and Information Conference; 2015. pp. 687–93. http://dx.doi.org/10.1109/SAI.2015.7237216.
  • [2] Joshi VS. Analysis of retinal vessel networks using quantitative descriptors of vascular morphology [Ph.D. thesis]. USA: University of Iowa; 2012, https://ir.uiowa.edu/etd/3321/.
  • [3] Khansari MM, O'Neill W, Lim J, Shahidi M. Method for quantitative assessment of retinal vessel tortuosity in optical coherence tomography angiography applied to sickle cell retinopathy. Biomed Opt Express 2017;8(8):3796– 806. http://dx.doi.org/10.1364/boe.8.003796.
  • [4] Annunziata R, Reglin B, Pries A, Trucco E. Hemodynamic parameters and vessel tortuosity: an investigation with a mesenterial vascular network. J Model Ophthalmol 2017;1 (4):62–8.
  • [5] El Abbadi NK, Al Saadi EH. Automatic retinal vessel tortuosity measurement. J Comput Sci 2013;9(11):1456–60. http://dx.doi.org/10.3844/jcssp.2013.1456.1460.
  • [6] Bhuiyan A, Nath B, Ramamohanarao K, Kawasaki R, Wong TY. Automated analysis of retinal vascular tortuosity on color retinal images. J Med Syst 2012;36:689–97. http://dx.doi.org/10.1007/s10916-010-9536-6.
  • [7] Bhargava M, Wong TY. Retinal physician: current concepts in hypertensive retinopathy; 2013, https://www.retinalphysician.com/issues/2013/nov-dec/ current-concepts-in-hypertensiveretinopathy.
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  • [11] Theng Oh K. Ophthalmologic manifestations of hypertension; 2016, https://emedicine.medscape.com/article/ 1201779-overview.
  • [12] Mondal RN, Matin MA, Rani M, Hossain MZ, Shaha AC, Singh RB, et al. Prevalence and risk factors of hypertensive retinopathy in hypertensive patients. J Hypertens: Open Access 2017;6:1–5. http://dx.doi.org/10.4172/2167-1095.1000241.
  • [13] Ong YT, Wong TY, Klein R, Klein BE, Mitchell P, Sharrett AR, et al. Hypertensive retinopathy and risk of stroke. Hypertension 2013;62(4):706–11. http://dx.doi.org/10.1161/HYPERTENSIONAHA.113.01414.
  • [14] Chakravarty A, Sivaswamy J. A novel approach for quantification of retinal vessel tortuosity using quadratic polynomial decomposition. Indian Conference on Medical Informatics and Telemedicine; 2013. pp. 7–12. http://dx.doi.org/10.1109/IndianCMIT.2013.6529399.
  • [15] Joshi V, Reinhardt JM, Abràmoff MD. Automated measurement of retinal blood vessel tortuosity. Proceedings of the SPIE, 7624: Medical Imaging 2010: Computer-Aided Diagnosis; 2010. http://dx.doi.org/10.1117/12.844641. pp. 76243A-1–76243A-9.
  • [16] Jameel SA, Shanavas AR. Retinal vessel tortuosity evaluation using connected component analysis for fundus images. International Conference on Communication and Signal Processing; 2016. pp. 173–6. http://dx.doi.org/10.1109/ICCSP.2016.7754115.
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  • [22] Nirmala SR, Chetia S. Retinal blood vessel tortuosity measurement for analysis of hypertensive retinopathy. International Conference on Innovations in Electronics, Signal Processing and Communication (IESC); 2017. pp. 45– 50. http://dx.doi.org/10.1109/IESPC.2017.8071862.
  • [23] Cheung CY, Zheng Y, Hsu W, Lee ML, Lau QP, Mitchell P, et al. Retinal vascular tortuosity, blood pressure, and cardiovascular risk factors. Ophthalmology 2011;118(5):812– 8. http://dx.doi.org/10.1016/j.ophtha.2010.08.045.
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  • [26] [RET-TORT]. Available from http://bioimlab.dei.unipd.it/Retinal%20Vessel% 20Tortuosity.htm.
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  • [28] Abdalla M. Evaluating retinal blood vessels' abnormal tortuosity in digital image fundus [MRes thesis]. University of Lincoln; 2016, http://eprints.lincoln.ac.uk/23684/.
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Uwagi
PL
Opracowanie rekordu w ramach umowy 509/P-DUN/2018 ze środków MNiSW przeznaczonych na działalność upowszechniającą naukę (2019).
Typ dokumentu
Bibliografia
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