An integrated gas removing system for microfluidic application. Design and evaluation

• Autorzy: Hofman I. M. , Ziółkowska K. , Dybko A. , Brzózka Z.
• Języki publikacji: EN

Abstrakty

EN

Microfluidic systems are used in a wide range of applications, including medical diagnostics, cell engineering and bioanalytics. In this work we focused on “Lab-on-a-chip” microsystems for cell cultivation. A troublesome problem of gas bubbles entering microdevices causing signal interferences and cells damage was emphasized. A novel, integrated debubbler in the form of cylindrical traps covered with thin PDMS membrane was designed and manufactured. Demonstrated debubbler was successfully applied in a long-lasting culture of HT-29 cell aggregates.

Słowa kluczowe

EN

gas removing system; debubbler; debubbling system; lab-on-a-chip; microfluidics; long-term cell culture; cell spheroids; HT-29 cells

• Wydawca: Foundation for Young Scientists
• Czasopismo: Challenges of Modern Technology
• Rocznik: 2013
• Tom: Vol. 4, no. 3
• Strony: 10--15
• Opis fizyczny: Bibliogr. 34 poz., rys. , il.

Twórcy

autor

Hofman I. M.

• Faculty of Chemistry, Warsaw University of Technology, Warsaw, Noakowskiego 3 Street.

autor

Ziółkowska K.

• Faculty of Chemistry, Warsaw University of Technology, Warsaw, Noakowskiego 3 Street.

autor

Dybko A.

• Faculty of Chemistry, Warsaw University of Technology, Warsaw, Noakowskiego 3 Street.

autor

Brzózka Z.

• Faculty of Chemistry, Warsaw University of Technology, Warsaw, Noakowskiego 3 Street.

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