Fish collagen and chitosan mixtures as a promising biomaterial for potential use in medicine and cosmetic industry

• Autorzy: Sionkowska Alina , Musiał Katarzyna , Gadomska Magdalena , Adamiak Katarzyna

Identyfikatory

DOI

10.34821/eng.biomat.164.2022.16-24

• Języki publikacji: EN

Abstrakty

EN

For the last three decades, an increasing interest in new materials based on blends of two or more polymers has been observed. Fish skin collagen and chitosan are constantly highly popular among scientists. This study aimed to obtain thin films from mixtures of low and medium molecular weight chitosan with fish collagen in three different ratios and examine their features for potential use in medicine and cosmetic industry. Polymer blends in ratios 25:75, 50:50, and 75:25 were made to obtain thin films. The infrared spectroscopy, mechanical properties study, contact angle measurements, topographic imaging, and swelling test were used to characterize the features of the films. A statistical appraisal of the results was conducted with the Q-Dixon’s test. The infrared spectroscopy analysis showed that in the IR spectra of the examined biomaterials, there are shifts in the bands positions proving intermolecular interactions between collagen and chitosan in the blends. The mechanical properties in the mixtures were different from those of a single biopolymer film. Hydrophilicity and polarity of the blends decrease with the increasing collagen content, which may suggest that the adhesion to the skin will be enhanced. The surface topography of the obtained films varies depending on the ratio of biopolymers in the mixtures. The swelling tests indicated that chitosan absorbs more water than collagen. The properties of the films made of collagen-chitosan mixtures vary depending on the molecular weight of chitosan and the content of each biopolymer in the blend.

Słowa kluczowe

EN

collagen; chitosan; blends; medicine; cosmetics

• Wydawca: Polish Society for Biomaterials in Cracow
• Czasopismo: Engineering of Biomaterials
• Rocznik: 2022
• Tom: vol. 25, no. 164
• Strony: 16--24
• Opis fizyczny: Bibliogr. 25 poz., rys., wykr., tab.

Twórcy

autor

Sionkowska Alina

• Department of Chemistry of Biomaterials and Cosmetics, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland

• https://orcid.org/0000-0002-1551-2725

autor

Musiał Katarzyna

• Department of Chemistry of Biomaterials and Cosmetics, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland

• https://orcid.org/0000-0002-3596-602X

autor

Gadomska Magdalena

• Department of Chemistry of Biomaterials and Cosmetics, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland

• https://orcid.org/0000-0001-9214-8931

autor

Adamiak Katarzyna

• WellU, Sp. z o.o., Wielkopolska 280, 81-531 Gdynia, Poland

• https://orcid.org/0000-0002-2386-603X

Bibliografia

• [1] Sionkowska A., Lewandowska K.: Biopolimery (2016). Accessed: Jan. 24, 2022. [Online]. Available: https://repozytorium.umk. pl/handle/item/3016
• [2] Sionkowska A.: Current research on the blends of natural and synthetic polymers as new biomaterials: Review. Progress in Polymer Science (Oxford) 36 (2011) 1254-1276.
• [3] Sionkowska A., Lewandowska K., Grabska S., Kaczmarek B., Michalska M.: Physico-chemical properties of three-component mixtures based on chitosan, hyaluronic acid and collagen. Molecular Crystals and Liquid Crystals 640 (2016) 21-29.
• [4] Mohan S., Oluwafemi O.S., Kalarikkal N., Thomas S., Songca S.P.: Biopolymers – Application in Nanoscience and Nanotechnology, (2016). London: IntechOpen.
• [5] Gaspar-Pintiliescu A., Stanciuc A.M., Craciunescu O.: Natural composite dressings based on collagen, gelatin and plant bioactive compounds for wound healing: A review. International Journal of Biological Macromolecules 138 (2019) 854-865.
• [6] Avila Rodríguez M.I., Rodríguez Barroso L.G., Sánchez M.L.: Collagen: A review on its sources and potential cosmetic applications. Journal of Cosmetic Dermatology 17 (2018) 20-26.
• [7] Sionkowska A.: Collagen blended with natural polymers: Recent advances and trends. Progress in Polymer Science 122 (2021) 101452.
• [8] Zhang J., Duan R., Tian Y., Konno K.: Characterisation of acid- -soluble collagen from skin of silver carp (Hypophthalmichthys molitrix). Food Chemistry 116 (2009) 318-322.
• [9] Liu D., Zhou P., Li T., Regenstein J.M.: Comparison of acid- -soluble collagens from the skins and scales of four carp species. Food Hydrocolloids: 41 (2014) 290-297.
• [10] Faralizadeh S., Rahimabadi E.Z., Bahrami S.H., Hasannia S.: Extraction, characterization and biocompatibility evaluation of collagen from silver carp (Hypophthalmichthys molitrix) skin by-product. Sustainable Chemistry and Pharmacy 22 (2021)
• [11] Sionkowska A., Adamiak K., Musial K., Gadomska M.: Collagen based materials in cosmetic applications: A review. Materials 13 (2020) 1-15.
• [12] Sionkowska A., Lewandowska K., Adamiak K.: The influence of uv light on rheological properties of collagen extracted from silver carp skin. Materials 13 (2020) 1-10.
• [13] Sionkowska A., Wisniewski M., Skopinska J., Kennedy C.J., Wess T.J.: Molecular interactions in collagen and chitosan blends. Biomaterials 25 (2004) 795-801.
• [14] Kaczmarek B., Sionkowska A.: Chitosan/collagen blends with inorganic and organic additive - A review. Advances in Polymer Technology 37 (2017) 2367-2376.
• [15] Haifei S., Xingang W., Shoucheng W., Zhengwei M., Chuangang Y., Chunmao H.: The effect of collagen-chitosan porous scaffold thickness on dermal regeneration in a one-stage grafting procedure. Journal of the Mechanical Behavior of Biomedical Materials: 29 (2014) 114-125.
• [16] Li W., Long Y., Liu Y., Long K., Liu S., Wang Z., Wang Y., Ren L.: Fabrication and characterization of chitosan-collagen crosslinked membranes for corneal tissue engineering. Journal of Biomaterials Science, Polymer Edition 25 (2014) 1962-1972.
• [17] Bi L., Cao Z., Hu Y., Song Y., Yu L., Yang B., Mu J., Huang Z., Han Y.: Effects of different cross-linking conditions on the properties of genipin-cross-linked chitosan/collagen scaffolds for cartilage tissue engineering. Journal of Materials Science: Materials in Medicine 22 (2011) 51-62.
• [18] Sun Y., Yang C., Zhu X., Wang J. J., Liu X.Y., Yang X.P., An X.W., Liang J., Dong H.J., Jiang W., Chen C., Wang Z.G., Sun H.T., Tu Y., Zhang S., Chen F., Li X. H.: 3D printing collagen/chitosan scaffold ameliorated axon regeneration and neurological recovery after spinal cord injury. Journal of Biomedical Materials Research - Part A 107 (2019) 1898-1908.
• [19] Wang D., Wang M., Wang A., Li J., Li X., Jian H., Bai S., Yin J.: Preparation of collagen/chitosan microspheres for 3D macrophage proliferation in vitro. Colloids and Surfaces A: Physicochemical and Engineering Aspects: 572 (2019) 266-273.
• [20] Sionkowska A., Kaczmarek B., Michalska M., Lewandowska K., Grabska S.: Preparation and characterization of collagen/chitosan/ hyaluronic acid thin films for application in hair care cosmetics. Pure and Applied Chemistry 89 (2017) 1829-1839.
• [21] Brower V.: The biochemistry of beauty. The science and pseudo-science of beautiful skin. EMBO Reports 3 (2002) 712-714.
• [22] Guillerme J.B., Couteau C., Coiffard L.: Applications for marine resources in cosmetics. Cosmetics 4 (2017) 1-15.
• [23] Thongchai K., Chuysinuan P., Thanyacharoen T., Techasakul S., Ummartyotin S.: Characterization, release, and antioxidant activity of caffeic acid-loaded collagen and chitosan hydrogel composites. Journal of Materials Research and Technology 9 (2020) 6512-6520.
• [24] Sharkawy A., Barreiro M.F., Rodrigues A.E.: New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application. Colloids and Surfaces A: Physicochemical and Engineering Aspects 616 (2021)
• [25] Schlotmann K., Kaeten M., Black A.F., Damour O., Waldmann- -Laue M., Förster T.: Cosmetic efficacy claims in vitro using a three- -dimensional human skin model. International Journal of Cosmetic Science 23 (2001) 309-318.

Uwagi

Opracowanie rekordu ze środków MEiN, umowa nr SONP/SP/546092/2022 w ramach programu „Społeczna odpowiedzialność nauki” - moduł: Popularyzacja nauki i promocja sportu (2022-2023)