Novel conversion of 4-aminoquinolines to new tricyclic (R,S)-3-methylazeto[3,2-c] quinolin-2(2aH)-ones and versatile one step synthesis of N-(quinolin-4-yl) carbamates from 4-aminoquinolines

• Autorzy: Kotadiya V. C. , Viradiya D. J. , Baria B. H. , Kanzariya J. S. , Kakadiya R. , Shah A.
• Języki publikacji: EN

Abstrakty

EN

Reaction of 4-aminoquinolines with 4-nitrophenyl chloroformate have resulted in finding a novel transformation of 4-aminoquinolines to tricyclic (R,S)-3-methylazeto[3,2-c]quinolin-2(2aH)-ones. The structure of azeto-quinolinone was determined via spectroscopic and chemical methods. Various alcohols were used as nucleophiles to open the 1-azetinone ring to give the corresponding N-(quinolin-4-yl)carbamates in good yields. We also found a new and versatile one step synthesis of N-(quinolin-4-yl)carbamates by reacting 4-aminoquinolines with alkyl chloroformates in the presence of anhyd K2CO3 in acetonitrile.

Słowa kluczowe

EN

quinolin; carbamates; azeto-quinolinone; aminoquinolines

• Wydawca: Przedsiębiorstwo Wydawnictw Naukowych "DARWIN"
• Czasopismo: International Letters of Chemistry, Physics and Astronomy
• Rocznik: 2014
• Tom: Vol. 11, iss. 3
• Strony: 265--276
• Opis fizyczny: Bibliogr. 21 poz., rys., tab., wz.

Twórcy

autor

Kotadiya V. C.

• Department of Chemistry (UGC-SAP & DST-FIST Sponsored), Saurashtra University, Rajkot - 360005, Gujarat, India. National Facility for Drug Discovery Center, Saurashtra University Rajkot - 360005, Gujarat, India

autor

Viradiya D. J.

• Department of Chemistry (UGC-SAP & DST-FIST Sponsored), Saurashtra University, Rajkot - 360005, Gujarat, India. National Facility for Drug Discovery Center, Saurashtra University Rajkot - 360005, Gujarat, India

autor

Baria B. H.

• Department of Chemistry (UGC-SAP & DST-FIST Sponsored), Saurashtra University, Rajkot - 360005, Gujarat, India. National Facility for Drug Discovery Center, Saurashtra University Rajkot - 360005, Gujarat, India

autor

Kanzariya J. S.

• Department of Chemistry (UGC-SAP & DST-FIST Sponsored), Saurashtra University, Rajkot - 360005, Gujarat, India. National Facility for Drug Discovery Center, Saurashtra University Rajkot - 360005, Gujarat, India

autor

Kakadiya R.

• Department of Chemistry (UGC-SAP & DST-FIST Sponsored), Saurashtra University, Rajkot - 360005, Gujarat, India. National Facility for Drug Discovery Center, Saurashtra University Rajkot - 360005, Gujarat, India

autor

Shah A.

• Department of Chemistry (UGC-SAP & DST-FIST Sponsored), Saurashtra University, Rajkot - 360005, Gujarat, India. National Facility for Drug Discovery Center, Saurashtra University Rajkot - 360005, Gujarat, India

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