Combined Spectral Resonances of Signaling Proteins’ Amino Acids in the ERK-MAP Pathway Reflect Unique Patterns That Predict Peak Photon Emissions and Universal Energies

• Autorzy: Persinger M.A. , Murugan N.J. , Karbowski L.M.

Identyfikatory

DOI

10.18052/www.scipress.com/ILCPA.43.10

• Języki publikacji: EN

Abstrakty

EN

The duality of matter-energy as particle-waves was applied to the classic ERK-MAP signaling pathways between the plasma cell membrane and the nucleus and was tested with Cosic’s Resonance Recognition Method. Spectral analyses of sequences of pseudopotentials that reflect de-localized electrons of amino acids for the 11 proteins in the pathway were computed. The spectral power density of the terminal protein (cFOS) was shown to be the average of the profiles of the precursor proteins. The results demonstrated that in addition to minute successive alterations in molecular structure wave-functions and resonant patterns can also describe complex molecular signaling pathways in cells. Different pathways may be defined by a single resonance profile. The separations between the peaks of wavelengths from Cosic’s predictions for photon emissions in the visible spectrum that define the ERK-MAP pathway were within the range of 10-20 J. This quantity has been shown to be a fundamental unit of energy within the universe. The involvement of photon patterns indicates that non-local effects could accompany the serial causality (locality) assumed to connect molecular pathways.

Słowa kluczowe

EN

10-20 J; Cosic Resonance Recognition Mechanism; ERK-MAP Signaling Pathway; Function; Particle-Wave Phenomena; photon emission

• Wydawca: Przedsiębiorstwo Wydawnictw Naukowych "DARWIN"
• Czasopismo: International Letters of Chemistry, Physics and Astronomy
• Rocznik: 2015
• Tom: Vol. 43
• Strony: 10--25
• Opis fizyczny: Bibliogr. 21 poz., rys., tab.

Twórcy

autor

Persinger M.A.

• Laurentian University, Sudbury, Ontario P3E 2C6, Canada

autor

Murugan N.J.

• Laurentian University, Sudbury, Ontario P3E 2C6, Canada

autor

Karbowski L.M.

• Laurentian University, Sudbury, Ontario P3E 2C6, Canada

Bibliografia

• [1] I. Cosic, IEEE Transactions on Biomedical Engineering 41 (1994) 1101-1114.
• [2] B. T Dotta, N. J. Murugan, L. M. Karbowski, R. M. Lafrenie, M. A. Persinger, Naturwissenschaften 101 (2014) 87-94.
• [3] A. D. Aczel, Entanglement: the Greatest Mystery in Physics Raincoast Books, Vancouver, 2002.
• [4] B. Albert, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter, Molecular Biology of the Cell Garland Science, N.Y., 2002.
• [5] I. Cosic, K. Lazar, D. Cosic, IEEE Transaction on NanoBioscience (2014) DOI: 10.1109/TNB.2014.2365851.
• [6] M. A. Persinger, S. A. Koren, International Letters of Chemistry, Physics and Astronomy 15 (2014) 80-86.
• [7] T. E. Decoursey, Physiological Reivews 83 (2002) 475-579.
• [8] M. A. Persinger, S. A. Koren, G. F. Lafreniere, NeuroQuantology 6 (2008) 262-271.
• [9] M. A. Persinger, International Letters of Chemistry, Physics and Astronomy 12 (2014) 1-10.
• [10] M. A. Persinger, Current Medicinal Chemistry 17 (2010) 3094-3098.
• [11] B. T. Dotta, C. A. Buckner, D. Cameron, R. M. Lafrenie, M. A. Persinger, General Physiology and Biophysics 30 (2011) 301-309.
• [12] M. A. Persinger, R. F. Lafrenie, International Letters of Chemistry, Physics and Astronomy 17 (2014) 67-77.
• [13] M. Levin, BioEssays 34 (2012) 205-217.
• [14] N. J. Murugan, L. M. Karbowski, R. M. Lafrenie, M. A. Persinger, Journal of Biophysical Chemistry, in press.
• [15] M. A. Persinger, S. A. Koren, International Journal of Neuroscience 117 (2007) 157-175.
• [16] S. A. Koren, B. T. Dotta, M. A. Persinger, The Open Astronomy Journal 7 (2014) 1-6.
• [17] C. Buckner, Effects of Electromagnetic Fields on Biological Processes are Spatial and Temporal Dependent, Ph.D. Biomolecular Sciences, Laurentian University, Sudbury, 2011.
• [18] B. T. Dotta, M. A. Persinger, Journal of Biophysical Chemistry 3 (2012) 72-80.
• [19] B. T. Dotta, N. J. Murugan, L. M. Karbowski, M. A. Persinger, International Journal of Physical Sciences 8 (2013) 1783-1787.
• [20] B. T. Dotta, C. A. Buckner, R. M. Lafrenie, M. A. Persinger, Brain Research 388 (2011) 77-88.
• [21] B. T. Dotta, R. M. Lafrenie, L. M. Karbowski, M. A. Persinger, General Physiology and Biophysics 33 (2014) 63-73.